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Pneumococcal disease in Europe (Pnc EURO)
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Milestones

WP1
Factors affecting the observed rates of invasive pneumococcal disease
WP2
Establishing novel methodology to measure pneumococcal antibodies
WP3
Upper respiratory tract carriage and transmission of pneumococci
WP4
Modelling of the effects of different vaccination strategies on Pnc carriage and invasive disease in different populations
WP5
The economic impact of different vaccination strategies on invasive pneumococcal disease
WP6
Pnc-EURO project management
Illustration of milestones (pdf 15 kb)

Tasks marked with green have been already achieved!

WP1: Factors affecting the observed rates of invasive pneumococcal disease

4/2001
Common study protocol completed
3/2002
Report on the observed rates of invasive Pnc disease
7/2002
Completion of data collection for system attributes
11/2002
The final data sets on invasive Pnc disease delivered
2/2003
Analysis of the representativeness of the data, and estimation of the actual rates of Pnc disease in connection with WP4
5/2003
Description of the structure of and differences between the surveillance systems completed
11/2003
Recommendations for development of a Pnc surveillance system

WP2: Establishing novel methodology to measure pneumococcal antibodies

11/2002
Optimised standardised assay developed
7/2003
Completed analysis of serological samples received from earlier Pnc studies
11/2003
Completed evaluation of correlates of protection

WP3: Upper respiratory tract carriage and transmission of pneumococci

1/2001
Completion of common study protocol
3/2001
Local and national ethical approval obtained
5-7/2002
Local carriage studies completed
9/2002
Completion of laboratory analysis of samples
11/2002
Analyses of the transmission models completed
11/2002
Results of the analyses delivered for modelling
11/2003
Reports on URT carriage and transmission of Pnc in Europe

WP4: Modelling of the effects of different vaccination strategies on Pnc carriage and invasive disease in different populations

5/2002
Mathematical transmission models formulated with specific tasks to be achieved
11/2002
Simulation models for Pnc transmission in the population implemented
1/2003
Analyses of the surveillance systems completed, results delivered to WP1
5/2003
Statistical analyses to derive parameters of the transmission models completed
11/2003
Evaluation of different vaccination strategies completed

WP5: The economic impact of different vaccination strategies on invasive pneumococcal disease

5/2002
Report on review of the economics of invasive pneumococcal disease
11/2002
Report of the cost-of-illness study containing country-specific costs estimates
1/2003
Analyses of the surveillance systems completed, results delivered to WP1
11/2003
Report of cost-effectiveness and cost-utility studies

WP6: Pnc-EURO project management

11/2001 and 11/2002 and 11/2003
External annual reports 4/2001
Database established 6/2001
Web-site established
10/2003
Final report and technology implementation plan (TIP)
10/2003
Co-ordination of the production of publications in high quality scientific journals
Tuija Leino: (09) 47 441
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00300 Helsinki

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© The Finnish National Public Health Institute 2001
Updated 20.12.2002 Editor