Publication Catalogue

Publications of the Department of Molecular Medicine 2008

A. Original articles and reviews

  1. Ahnström J, Axler O, Jauhiainen M, Salomaa V, Havulinna AS, Ehnholm C, Frikke-Schmidt R, Tybjaerg-Hansen A, Dahlbäck B: Levels of apolipoprotein M are not associated with the risk of coronary heart disease in two independent case-control studies. J Lipid Res 2008;49:1912-1917.
  2. Ahvenainen T, Lehtonen HJ, Lehtonen R, Vahteristo P, Aittomäki K, Baynam G, Dommering C, Eng C, Gruber SB, Grönberg H, Harvima R, Herva R, Hietala M, Kujala M, Kääriäinen H, Sunde L, Vierimaa O, Pollard PJ, Tomlinson IPM, Björck E, Aaltonen LA, Launonen V: Mutation screening of fumarate hydratase by multiplex ligation-dependent probe amplification: detection of exonic deletion in a patient with leiomyomatosis and renal cell cancer. CANCER GENET CYTOGENET 2008;183:83-88.
  3. Alimohammadi, M, Björklund, P, Hallgren, Å, Pöntynen, N, Szinnai, G, Shikama, N, Keller, MP, Ekwall, O, Kinkel, SA, Husebye, ES, Gustaffson, J, Rorsman, F, Peltonen, L, Betterle, C, Perheentupa, J, Åkerström, G, Westin, G, Scott, HS, Holländer, G, Kämpe, O: Autoimmune polyendocrine syndrome type 1 and NALP5, parathyroid autoantigen. N Engl J Med 2008;358:28-38.
  4. Anttila V, Nyholt DR, Kallela M, Artto V, Vepsäläinen S, Jakkula E, Wennerström A, Tikka-Kleemola P, Kaunisto MA, Hämäläinen E, Widen E, Terwilliger J, Merikangas K, Montgomery GW, Martin NG, Daly M, Kaprio J, Peltonen L, Farkkila M, Wessman M, Palotie A: Consistently replicating locus linked to migraine on 10q22-q23. Am J Hum Genet 2008;82:1051-1063.
  5. Auro K, Kristiansson K, Zethelius B, Berne C, Lannfelt L, Taskinen MR, Jauhiainen M, Perola M, Peltonen L, Syvänen AC: USF1 gene variants contribute to metabolic traits in men in a longitudinal 32-year follow-up study. Diabetologia 2008;51:464-472.
  6. Benyamin B, Perola M, Cornes BK, Madden PAF, Palotie A, Nyholt DR, Montgomery GW, Peltonen L, Martin NG, Visscher PM: Within-family outliers: segregating alleles or environmental effects? A linkage analysis of height from 5815 sibling pairs. Eur J Hum Genet 2008;16:516-524.
  7. Donner J, Pirkola S, Silander K, Kananen L, Terwilliger JD, Lönnqvist J, Peltonen L, Hovatta I: An association analysis of murine anxiety genes in humans implicates novel candidate genes for anxiety disorders. Biol Psychiatry 2008;64:672-680.
  8. Enattah, NS, Jensen, TG, Nielsen, M, Lewinski, R, Kuokkanen, M, Rasinperä, H, El-Shanti, H, Seo, JK, Alifrangis, M, Khalil, IF, Natah, A, Ali, A, Natah, S, Comas, D, Mehdi, SQ, Groop, L, Vestergaard, EM, Imtiaz, F, Rashed, MS, Meyer, B, Troelsen, J, Peltonen, L: Independent introduction of two lactase-persistence alleles into human populations reflects different history of adaption to milk culture. Am J Hum Genet 2008;82:57-72.
  9. Graner M, Kahri J, Varpula M, Salonen RM, Nyyssönen K, Jauhiainen M, Nieminen MS, Syvänne M, Taskinen MR: Apolipoprotein E polymorphism is associated with both carotid and coronary atherosclerosis in patients with coronary artery disease. Nutrition Metabolism and Cardiovasc Diseases 2008;18:271-277.
  10. Hallast P, Saarela J, Palotie A, Laan M: High divergence in primate-specific duplicated regions: Human and chimpanzee Chorionic Gonadotropin Beta genes. BMC Evolutionary Biology 2008(Jul):8.
  11. Hassler S, Peltonen L, Sandler S, Winqvist O: AIRE deficiency causes increased susceptibility to streptozotocin-induced murine type 1 diabetes. Scand J Immunol 2008;67:569-580.
  12. Hennah W, Thomson P, McQuillin A, Bass N, Loukola A, Anjorin A, Blackwood D, Curtis D, Deary IJ, Harris SE, Isometsä ET, Lawrence J, Lönnqvist J, Muir W, Palotie A, Partonen T, Paunio T, Pylkkö E, Robinson M, Soronen P, Suominen K, Suvisaari J, Thirumalai S, Clair DS, Gurling H, Peltonen L, Porteous D: DISC1 association, heterogeneity and interplay in schizophrenia and bipolar disorder. Molecular psychiatry 2008(Mar 4).
  13. Hintsanen M, Elovainio M, Puttonen S, Kivimäki M, Lehtimäki T, Kähönen M, Juonala M, Rontu R, Viikari JS, Raitakari OT, Keltikangas-Järvinen L: Val/Met polymorphism of the COMT gene moderates the association between job strain and early atherosclerosis in young men. J OCCUP ENVIRON MED 2008;50:649-657.
  14. Ilmarinen T, Kangas H, Kytömaa T, Eskelin P, Saharinen J, Seeler JS, Tanhuanpää K, Chan FYL, Slattery RM, Alakurtti K, Palvimo JJ, Ulmanen I: Functional interaction of AIRE with PIAS1 in transcriptional regulation. MOL IMMUNOL 2008;45:1847-1862.
  15. Jakkula E, Rehnström K, Varilo T, Pietiläinen OP, Paunio T, Pedersen NL, deFaire U, Järvelin MR, Saharinen J, Freimer N, Ripatti S, Purcell S, Collins A, Daly MJ, Palotie A, Peltonen L: The genome-wide patterns of variation expose significant substructure in a founder population. Am J Hum Genet 2008;83:787-794.
  16. Jalanko A, Braulke T: Neuronal ceroid lipofuscinoses. Biochim Biophys Acta 2008(Nov 24).
  17. Javahera P, Kääriäinen H, Kristoffersson U, Nippert I, Sequeiros J, Zirnmern R, Schmidtke J: EuroGentest: DNA-based testing for heritable disorders in Europe. Community Genetics 2008;11:75-120.
  18. Junttila MR, Li SP, Westermarck J: Phosphatase-mediated crosstalk between MAPK signalling pathways in the regulation of cell survival. FASEB J 2008;22:954-965.
  19. Kallio KAE, Buhlin K, Jauhiainen M, Keva R, Tuomainen AM, Klinge B, Gustafsson A, Pussinen PJ: Lipopolysaccharide associates with pro-atherogenic lipoproteins in periodontitis patients. Innate Immunity 2008;14:247-253.
  20. Kathiresan S, Melander O, Guiducci C, Surti A, Burtt NP, Rieder MJ, Cooper GM, Roos C, Voight BF, Havulinna AS, Wahlstrand B, Hedner T, Corella D, Tai ES, Ordovas JM, Berglund G, Vartiainen E, Jousilahti P, Hedblad B, Taskinen MR, Newton-Cheh C, Salomaa V, Peltonen L, Groop L, Altshuler DM, Orho-Melander M: Six new loci associated with blood low-density lipoprotein cholesterol, high-density lipoprotein cholesterol or triglycerides in humans. Nat Genet 2008;40:189-197.
  21. Keskitalo K, Tuorila H, Spector TD, Cherkas LF, Knaapila A, Kaprio J, Silventoinen K, Perola M: The Three-Factor Eating Questionnaire, body mass index, and responses to sweet and salty fatty foods: a twin study of genetic and environmental associations. Am J Clin Nutr 2008;88:263-271.
  22. Keskitalo, K, Silventoinen, K, Tuorila, H, Perola, M, Pietiläinen, KH, Rissanen, A, Kaprio, J: Genetic and environmental contributions to food use patterns of young adult twins. Physiol Behav 2008;93:235-42.
  23. Kilpinen H, Ylisaukko-Oja T, Hennah W, Palo OM, Varilo T, Vanhala R, Nieminen-von WT, von Wendt L, Paunio T, Peltonen L: Association of DISC1 with autism and Asperger syndrome. Molecular psychiatry 2008;13:187-196.
  24. Kristiansson K, Naukkarinen J, Peltonen L: Isolated populations and complex disease gene identification. Genome Biology 2008;9:109.
  25. Kristiansson, K, Ilveskoski, E, Lehtimäki, T, Peltonen, L, Perola, M, Karhunen, PJ: Association analysis of allelic variants of USF1 in coronary atherosclerosis. Arteriosclerosis, Thrombosis, and Vascular Biology 2008(Epub Feb14).
  26. Kristjansdottir, G, Sandling, JK, Bonetti, A, Roos, IM, Milani, L, Wang, C, Gustafsdottir, SM, Sigurdsson, S, Lundmark, A, Tienari, PJ, Koivisto, K, Elovaara, I, Pirttilä, T, Reunanen, M, Peltonen, L, Saarela, J, Hillert, J, Olsson, T, Landegren, U, Alcina, A, Fernandez, O, Leyva, L, Guerrero, M, Lucas, M, Izquierdo, G, Matesanz, F, Syvänen, AC: Interferon regulatory factor 5 (IRF5) gene variants are associated with Multiple Sclerosis in three distinct populations. J Med Genet 2008;45:362-369.
  27. Kumpula LS, Kumpula JM, Taskinen MR, Jauhiainen M, Kaski K, Ala-Korpela M: Reconsideration of hydrophobic lipid distributions in lipoprotein particles. CHEM PHYS LIPIDS 2008;155:57-62.
  28. Kuula H, Salo T, Pirilä E, Tuomainen AM, Jauhiainen M, Uitto VJ, Tjaderhane L, Pussinen PJ, Sorsa T: Porphyromonas gingivalis-induced periodontitis: local and systemic responses in MMP-8 knock-out mice. Infect Immun 2008(Nov 24).
  29. Lehto, M, Mäyränpää, MI, Pellinen, T, Ihalmo, P, Lehtonen, S, Kovanen, PT, Groop, PH, Ivaska, J, Olkkonen, VM: The R-Ras interaction partner ORP3 regulates cell adhesion. J Cell Sci 2008;121:695-705.
  30. Lettre G, Jackson AU, Gieger C, Schumacher FR, Berndt SI, Sanna S, Eyheramendy S, Voight BF, Butler JL, Guiducci C, Illig T, Hackett R, Heid IM, Jacobs KB, Lyssenko V, Uda M, Diabetes GI, FUSION, KORA, Prostate, LC, SardiNIA, Boehnke M, Chanock SJ, Groop LC, Hu FB, Isomaa B, Kraft P, Peltonen L, Salomaa V, Schlessinger D, Hunter DJ, Hayes RB, Abecasis GR, Wichmann HE, Mohlke KL, Hirschhorn JN: Identification of ten loci associated with height highlights new biological pathways in human growth. Nat Genet 2008;40:584-591.
  31. Lindh E, Lind SM, Lindmark E, Hassler S, Perheentupa J, Peltonen L, Winqvist O, Karlsson MCI: AIRE regulates T-cell-independent B-cell responses through BAFF. Proc Natl Acad Sci U S A 2008;105:18466-18471.
  32. Lorentzen AR, Smestad C, Lie BA, Oturai AB, Akesson E, Saarela J, Myhr KM, Vartdal F, Celius EG, Sorensen PS, Hillert J, Spurkland A, Harbo HF: The SH2D2A gene and susceptibility to multiple sclerosis. J NEUROIMMUNOL 2008;197:152-158.
  33. Loukola A, Broms U, Maunu H, Widen E, Heikkilä K, Siivola M, Salo A, Pergadia ML, Nyman E, Sammalisto S, Perola M, Agrawal A, Heath AC, Martin NG, Madden PAF, Peltonen L, Kaprio J: Linkage of nicotine dependence and smoking behavior on 10q, 7q and 11p in twins with homogeneous genetic background. Pharmacogenomics Journal 2008;8:209-219.
  34. Lu, AT, Ogdie, MN, Järvelin, MR, Moilanen, IK, Loo, SK, McCracken, JT, McGough, JJ, Yang, MH, Peltonen, L, Nelson, SF, Cantor, RM, Smalley, SL: Association of the cannabinoid receptor gene (CNR1) with ADHD and post-traumatic stress disorder. Am J Med Genet 2008(Epub Jan22).
  35. Lundmark PE, Liljedahl U, Boomsma DI, Mannila H, Martin NG, Palotie A, Peltonen L, Perola M, Spector TD, Syvänen AC: Evaluation of HapMap data in six populations of European descent. Eur J Hum Genet 2008;16:1142-1150.
  36. Lyly A, Marjavaara SK, Kyttälä A, Uusi-Rauva, K, Luiro K, Kopra O, Martinez LO, Tanhuanpää K, Kalkkinen N, Suomalainen A, Jauhiainen M, Jalanko A: Deficiency of the INCL protein Ppt1 (palmitoyl protein thioesterase 1) results in changes in ectopic F1-ATP synthase and altered cholesterol metabolism. Hum Mol Genet 2008;17:1406-1417.
  37. Magnusson PKE, Boman M, de Faire U, Perola M, Peltonen L, Pedersen NL: Genome-wide search for QTLs for apolipoprotein A-I level in elderly Swedish DZ twins: evidence of female-specific locus on 15q11-13. Eur J Hum Genet 2008;16:1103-1110.
  38. Markkanen A, Juutilainen J, Naarala J: Pre-exposure to 50Hz magnetic fields modifies menadione-induced DNA damage response in murine L929 cells. INT J RADIAT BIOL 2008;84:742-751.
  39. Mustelin L, Pietiläinen KH, Rissanen A, Sovijärvi AR, Piirilä P, Naukkarinen J, Peltonen L, Kaprio J, Yki-Järvinen H: Acquired obesity and poor physical fitness impair expression of genes of mitochondrial oxidative phosphorylation in monozygotic twins discordant for obesity. American journal of physiology. Endocrinology and metabolism 2008;295:E148-E154.
  40. Mäkelä SM, Jauhiainen M, Ala-Korpela M, Metso J, Lehto TM, Savolainen MJ, Hannuksela ML: HDL2 of heavy alcohol drinkers enhances cholesterol efflux from raw macrophages via phospholipid-rich HDL2b particles. Alcohol Clin Exp Res 2008;32:991-1000.
  41. Orho-Melander M, Melander O, Guiducci C, Perez-Martinez P, Corella D, Roos C, Tewhey R, Rieder MJ, Hall J, Abecasis G, Tai ES, Welch C, Arnett DK, Lyssenko V, Lindholm E, Saxena R, de Bakker PI, Burtt N, Voight BF, Hirschhorn JN, Tucker KL, Hedner T, Tuomi T, Isomaa B, Eriksson KF, Taskinen MR, Wahlstrand B, Hughes TE, Parnell LD, Lai CQ, Berglund G, Peltonen L, Vartiainen E, Jousilahti P, Havulinna AS, Salomaa V, Nilsson P, Groop L, Altshuler D, Ordovas JM, Kathiresan S: Common missense variant in the glucokinase regulatory protein gene (GCKR) is associated with increased plasma triglyceride and C-reactive protein but lower fasting glucose concentrations. Diabetes 2008(Aug 4).
  42. Paetau A, Honkala H, Salonen R, Ignatius J, Kestilä M, Herva R: Hydrolethalus syndrome: neuropathology of 21 cases confirmed by HYLS1 gene mutation analysis. J NEUROPATHOL EXP NEUROL 2008;67:750-762.
  43. Palo JU, Pirttimaa M, Bengs A, Johnsson V, Ulmanen I, Lukka M, Udd B, Sajantila A: The effect of number of loci on geographical structuring and forensic applicability of Y-STR data in Finland. Int J Legal Med 2008;122:449-456.
  44. Pellikka M, Närhi L, Perola M, Penttilä A, Karhunen P, Mikkelsson J: Platelet GPIb alpha, GPIV and vWF polymorphisms and fatal pre-hospital MI among middle-aged men. Journal of Thrombosis and Thrombolysis 2008;26:91-96.
  45. Pietiläinen KH, Naukkarinen J, Rissanen A, Saharinen J, Ellonen P, Keränen H, Suomalainen A, Gotz A, Suortti T, Yki-Järvinen H, Oresic M, Kaprio J, Peltonen L: Global transcript profiles of fat in monozygotic twins discordant for BMI: Pathways behind acquired obesity. PLoS medicine 2008;5:472-483.
  46. Pöntynen N, Strengell M, Sillanpää N, Saharinen J, Ulmanen I, Julkunen I, Peltonen L: Critical immunological pathways are downregulated in APECED patient dendritic cells. J MOL MED 2008;86:1139-1152.
  47. Rantanen E, Hietala M, Kristoffersson U, Nippert I, Schmidtke J, Sequeiros J, Kääriäinen H: Regulations and practices of genetic counselling in 38 European countries: the perspective of national representatives. Eur J Hum Genet 2008;16:1208-1216.
  48. Rantanen E, Hietala M, Kristoffersson U, Nippert I, Schmidtke J, Sequeiros J, Kääriäinen H: What is ideal genetic counselling? A survey of current international guidelines. Eur J Hum Genet 2008;16:445-452.
  49. Rehnstrom K, Ylisaukko-Oja T, Vanhala R, von Wendt L, Peltonen L, Hovatta I: No association between common variants in glyoxalase 1 and autism spectrum disorders. American Journal of Medical Genetics. Part B, Neuropsychiatric Genetics 2008;147:124-127.
  50. Rehnström K, Ylisaukko-Oja T, Nummela I, Ellonen P, Kempas E, Vanhala R, von Wendt L, Järvelä I, Peltonen L: Allelic variants in HTR3C show association with autism. American Journal of Medical Genetics. Part B, Neuropsychiatric Genetics 2008(Nov 26).
  51. Ripatti S, Becker T, Bickeboller H, Dominicus A, Fischer C, Humphreys K, Jonasdottir G, Moreau Y, Olsson M, Ploner A, Sheehan N, Van Steen K, Baur M, van Duijn C, Palmgren J: GENESTAT: an information portal for design and analysis of genetic association studies. Eur J Hum Genet 2008(Nov 12).
  52. Ripatti S, Mäkelä P: Conditional models accounting for regression to the mean in observational multi-wave panel studies on alcohol consumption. Addiction 2008;103:24-31.
  53. Saarela J, Jung G, Hermann M, Nimpf J, Schneider WJ: The patatin-like lipase family in Gallus gallus. BMC Genomics 2008;9:281.
  54. Sammalisto S, Hiekkalinna T, Schwander K, Kardia S, Weder AB, Rodriguez BL, Doria A, Kelly JA, Bruner GR, Harley JB, Redline S, Larkin EK, Patel SR, Ewan AJ, Weber JL, Perola M, Peltonen L: Genome-wide linkage screen for stature and body mass index in 3.032 families: evidence for sex- and population-specific genetic effects. Eur J Hum Genet 2008(Sep 10).
  55. Samyn H, Moerland M, van Gent T, van Haperen R, Metso J, Grosveld F, Jauhiainen M, van Tol A, de Crom R: Plasma phospholipid transfer activity is essential for increased atherogenesis in PLTP transgenic mice: a mutation-inactivation study. J Lipid Res 2008;49:2504-2512.
  56. von Schantz C, Saharinen J, Kopra O, Cooper JD, Gentile M, Hovatta I, Peltonen L, Jalanko A: Brain gene expression profiles of Cln1 and Cln5 deficient mice unravels common molecular pathways underlying neuronal degeneration in NCL diseases. BMC Genomics 2008(9):146.
  57. Schgoer W, Mueller T, Jauhiainen M, Wehinger A, Gander R, Tancevski I, Salzmann K, Eller P, Ritsch A, Hatlmayer M, Ehnholm C, Patsch JR, Foeger B: Low phopsholipid transfer protein (PLTP) is a risk factor for peripheral atherosclerosis. Atherosclerosis 2008;196:219-226.
  58. Siitonen HA, Sotkasiira J, Biervliet M, Benmansour A, Capri Y, Cormier-Daire V, Crandall B, Hannula-Jouppi K, Hennekam R, Herzog D, Keymolen K, Lipsanen-Nyman M, Miny P, Plon SE, Riedl S, Sarkar A, Vargas FR, Verloes A, Wang LL, Kääriäinen H, Kestilä M: The mutation spectrum in RECQL4 diseases. Eur J Hum Genet 2008(Aug 20).
  59. Silander K, Alanne M, Kristiansson K, Saarela O, Ripatti S, Auro K, Karvanen J, Kulathinal S, Niemelä M, Ellonen P, Vartiainen E, Jousilahti P, Saarela J, Kuulasmaa K, Evans A, Perola M, Salomaa V, Peltonen L: Gender differences in genetic risk profiles for cardiovascular disease. PLoS ONE 2008(Oct 31).
  60. Silander K, Saarela J: Whole genome amplification with phi29 DNA polymerase to enable genetic or genomic analysis of samples of low DNA yield. Methods in Molecular Biology 2008;439:1-18.
  61. Silventoinen K, Magnusson PKE, Tynelius P, Kaprio J, Rasmussen F: Heritability of body size and muscle strength in young adulthood: A study of one million Swedish men. Genet Epidemiol 2008;32:341-349.
  62. Soronen P, Silander K, Antila M, Palo OM, Tuulio-Henriksson A, Kieseppä T, Ellonen P, Wedenoja J, Turunen JA, Pietiläinen OP, Hennah W, Lönnqvist J, Peltonen L, Partonen T, Paunio T: Association of a nonsynonymous variant of DAOA with visuospatial ability in a bipolar family sample. Biol Psychiatry 2008;64:438-442.
  63. Sulonen AM, Kallio SP, Ellonen P, Suvela M, Elovaara I, Koivisto K, Pirttilä T, Reunanen M, Tienari PJ, Palotie A, Peltonen L, Saarela J: No evidence for shared etiology in two demyelinative disorders, MS and PLOSL. J NEUROIMMUNOL 2008(Nov 17).
  64. Tallila J, Jakkula E, Peltonen L, Salonen R, Kestilä M: Identification of CC2D2A as a Meckel syndrome gene adds an important piece to the ciliopathy puzzle. Am J Hum Genet 2008;82:1361-1367.
  65. Tiainen KM, Perola M, Kovanen VM, Sipilä S, Tuononen KA, Rikalainen K, Kauppinen MA, Widen EIM, Kaprio J, Rantanen T, Kujala UM: Genetics of maximal walking speed and skeletal muscle characteristics in older women. Twin Research and Human Genetics 2008;11:321-334.
  66. Tuomainen AM, Jauhiainen M, Kovanen PT, Metso J, Paju S, Pussinen PJ: Aggregatibacter actinomycetemcomitans induces MMP-9 expression and proatherogenic lipoprotein profile in apoE-deficient mice. Microb Pathog 2008;44:111-117.
  67. Uusi-Rauva K, Luiro K, Tanhuanpää K, Kopra O, Martin-Vasallo P, Kyttälä A, Jalanko A: Novel interactions of CLN3 protein link Batten disease to dysregulation of fodrin-Na(+), K(+) ATPase complex. Exp Cell Res 2008(Jun 28).
  68. Valli-Jaakkola K, Suviolahti E, Schalin-Jäntti C, Ripatti S, Silander K, Oksanen L, Salomaa V, Peltonen L, Kontula K: Further evidence for the role of ENPP1 in obesity: association with morbid obesity in Finns. Obesity 2008(Jun 12).
  69. Varjosalo M, Björklund M, Cheng F, Syvänen H, Kivioja T, Kilpinen S, Sun Z, Kallioniemi O, Stunnenberg HG, He WW, Ojala P, Taipale J: Application of active and kinase-deficient kinome collection for identification of kinases regulating hedgehog signaling. Cell 2008;133:537-548.
  70. Varjosalo M, Taipale J: Hedgehog: functions and mechanisms. GENES DEV 2008;15:2454-2472.
  71. Vuorela PE, Penttinen MT, Hietala MH, Laine JO, Huoponen KA, Kääriäinen HA: A familial CHARGE syndrome with a CHD7 nonsense mutation and new clinical features. CLIN DYSMORPHOL 2008;17:249-253.
  72. Wedenoja J, Loukola A, Tuulio-Henriksson A, Paunio T, Ekelund J, Silander K, Varilo T, Heikkilä K, Suvisaari J, Partonen T, Lönnqvist J, Peltonen L: Replication of linkage on chromosome 7q22 and association of the regional Reelin gene with working memory in schizophrenia families. Molecular psychiatry 2008;13:673-684.
  73. Yan D, Mäyränpää MI, Wong J, Perttilä J, Lehto M, Jauhiainen M, Kovanen PT, Ehnholm C, Brown AJ, Olkkonen VM: OSBP-related protein 8 (ORP8) suppresses ABCA1 expression and cholesterol efflux from macrophages. J Biol Chem 2008(283):332-340.
  74. Yan, D, Olkkonen, VM: Characteristics of oxysterol binding proteins. INT REV CYTOL 2008;265:253-285.
  75. Ye D, Kraaijeveld AO, Grauss RW, Willems SM, van Vark-van ZLC, de Jager SCA, Jauhiainen M, Kuivenhoven JA, Dallinga-Thie GM, Atsma DE, Hogendoorn PCW, Biessen EAL, Van Berkel TJC, Jukema JW, van Eck M: Reduced leucocyte cholesteryl ester transfer protein expression in acute coronary syndromes. J Intern Med 2008;264:571-585.
  76. Yu, X, Koczan, D, Sulonen, AM, Akkad, DA, Kroner, A, Comabella, M, Costa, G, Corongiu, D, Goertsches, R, Camina-Tato, M, Thiesen, HJ, Nyland, HI, Märk, SJ, Montalban, X, Rieckmann, P, Marrosu, MG, Myhr, KM, Epplen, JT, Saarela, J, Ibrahim, SM: mtDNA nt13708A variant increases the risk of Multiple Sclerosis. PLoS ONE 2008;3:e1530.
  77. Yuille M, van Ommen GJ, Brechot C, Cambon-Thomsen A, Dagher G, Landegren U, Litton JE, Pasterk M, Peltonen L, Taussig M, Wichmann HE, Zatloukal K: Biobanking for Europe. Briefings in Bioinformatics 2008;9:14-24.

B. Original articles and reviews published in domestic languages

  1. Hovatta I, Paunio T: Mieli, keho ja geenit. Duodecim 2008;124:675-677.

D. Other publications

  1. Badeau MH, Badeau R, Jauhiainen M, Tikkanen MJ: SteroidhHormone-fatty acid esters and bone [Letter]. J BONE MINER RES 2008(Nov 23).
  2. Ehnholm C, Jauhiainen M, Olkkonen V, Ikonen E, Kovanen P: Preface to the proceedings of the satellite symposium of the EAS 76th Congress and the XVth Paavo Nurmi Symposium [Editorial]. Ann Med 2008;40:4.

E. Theses

  1. Alanne M: Studies of the genetic epidemiology of cardiovascular disease: focus on inflammatory candidate genes [Dissertation]. Helsinki: National Public Health Institute, 2008. (Publications of the National Public Health Institute A 13/2008).
  2. Keskitalo K: A matter of taste - Genetic and environmental influences on responses to sweetness [Dissertation]. Helsinki: National Public Health Institute, 2008. (Publications of the National Public Health Institute A 5/2008).
  3. Kristiansson K: Genetics of cardiovascular disease: A candidate gene study of USF1 [Dissertation]. Helsinki: National Public Health Institute, 2008. (Publications of the National Public Health Institute A 8/2008).
  4. Lyly A: Molecular interactions underlying neuronal ceroid lipofuscinoses CLN1 and CLN5 [Dissertation]. Helsinki: National Public Health Institute, 2008. (Publications of the National Public Health Institute A 17/2008).
  5. Naukkarinen J: Molecular background of common dyslipidemias [Dissertation]. Helsinki: National Public Health Institute, 2008. (Publications of the National Public Health Institute A 7/2008).
  6. Sammalisto S: Search for genetic variants influencing human height [Dissertation]. Helsinki: National Public Health Institute, 2008. (Publications of the National Public Health Institute A 1/2008).
  7. Siitonen A: Molecular genetics of RECQL4 syndromes . Helsinki: National Public Health Institute, 2008. (Publications of the National Public Health Institute A 4/2008).
  8. Varjosalo M: The Mechanisms of hedgehog signal transduction [Dissertation]. Helsinki: National Public Health Institute, 2008. (Publications of the National Public Health Institute A 12/2008).