Pharmacological treatment during AMI and in secondary prevention: the scientific evidence

Table 14. Postmenopausal estrogens: effect on mortality.
STUDIES
[OBSERVATIONAL]		 DRUG No. PATIENTS FOLLOW-UP VAR. P
SULLIVAN (1988) [90] ESTROGENS 2,188 - -56% 0.002
GRUCHOW (1988) [32] ESTROGENS 933 - - 52% 0.05
McFARLAND (1989) [60] ESTROGENS 345 - - 50% <0.01
HERS (1998) [43] ESTROGEN + PROGESTIN vs PLACEBO 2,763 4.1 YEARS +6% NS

 

ACC/AHA GUIDELINES

  • Lacking clear results, one should respect the patient's preference

ANMCO-SIC CLINICAL GUIDELINES