Index

Hardy-Weinberg equilibrium tests in the subcohort for SNPs of the 10Q11_21 gene:

  1. 10Q11_21_MG_428 (rs1746048)
  2. 10Q11_21_MG_429 (rs1746049)
  3. 10Q11_21_MG_432 (rs2146807)
  4. 10Q11_21_MG_439 (rs501120)
  5. 10Q11_21_MG_440 (rs559580)
  6. 10Q11_21_MG_443 (rs687175)
  7. 10Q11_21_MG_456 (rs513391)
  8. 10Q11_21_MG_458 (rs622472)

10Q11_21_MG_428  (rs1746048)

RUA cohort N N
miss		 Allele
frequencies		 Genotype distribution p-value
C/C C/T T/T
C T O E O E O E
FIN-ATB 21 1037 9 1709 347 708 710 293 288 27 29 0.656
FIN-FIN 03 434 2 722 142 303 302 116 119 13 12 0.726
24 466 6 762 158 314 316 134 131 12 14 0.631
Total 900 8 1484 300 617 617 250 250 25 25 1.000
FRA-PRI 21 170 4 279 53 118 117 43 45 5 4 0.573
SWE-NSW 02 77 0 127 27 54 52 19 22 4 2 0.117
03 89 1 157 19 69 70 19 17 0 1 0.363
Total 166 1 284 46 123 122 38 40 4 3 0.746
UNK-BEL 21 145 2 248 38 109 108 30 33 4 3 0.469
Total 2418 24 4004 784 1675 1674 654 656 65 64 0.942

10Q11_21_MG_429  (rs1746049)

RUA cohort N N
miss		 Allele
frequencies		 Genotype distribution p-value
C/C C/T T/T
C T O E O E O E
FIN-ATB 21 1037 9 1774 282 764 765 246 243 18 19 0.791
FIN-FIN 03 434 2 763 101 336 337 91 89 5 6 0.819
24 466 5 802 120 349 349 104 104 8 8 1.000
Total 900 7 1565 221 685 686 195 194 13 14 0.881
FRA-PRI 21 170 4 279 53 118 117 43 45 5 4 0.572
SWE-NSW 02 77 0 134 20 59 58 16 17 2 1 0.610
03 89 1 158 18 70 71 18 16 0 1 0.588
Total 166 1 292 38 129 129 34 34 2 2 1.000
UNK-BEL 21 145 2 250 36 111 109 28 31 4 2 0.244
Total 2418 23 4160 630 1807 1806 546 547 42 41 0.929

10Q11_21_MG_432  (rs2146807)

RUA cohort N N
miss		 Allele
frequencies		 Genotype distribution p-value
T/T T/C C/C
T C O E O E O E
FIN-ATB 21 1037 10 1868 186 848 849 172 169 7 8 0.708
FIN-FIN 03 434 3 798 64 368 369 62 59 1 2 0.494
24 466 5 844 78 387 386 70 71 4 3 0.761
Total 900 8 1642 142 755 756 132 131 5 6 0.825
FRA-PRI 21 170 4 287 45 123 124 41 39 2 3 0.542
SWE-NSW 02 77 1 134 18 59 59 16 16 1 1 1.000
03 89 2 166 8 79 79 8 8 0 0 1.000
Total 166 3 300 26 138 138 24 24 1 1 1.000
UNK-BEL 21 145 3 240 44 102 101 36 37 4 3 0.749
Total 2418 28 4337 443 1966 1968 405 402 19 21 0.720

10Q11_21_MG_439  (rs501120)

RUA cohort N N
miss		 Allele
frequencies		 Genotype distribution p-value
T/T T/C C/C
T C O E O E O E
FIN-ATB 21 1037 53 1669 299 712 708 245 254 27 23 0.267
FIN-FIN 03 434 5 717 141 301 300 115 118 13 12 0.606
24 466 19 748 146 314 313 120 122 13 12 0.730
Total 900 24 1465 287 615 613 235 240 26 24 0.542
FRA-PRI 21 170 7 279 47 120 119 39 40 4 3 0.536
SWE-NSW 02 77 1 126 26 54 52 18 22 4 2 0.219
03 89 2 156 18 69 70 18 16 0 1 0.586
Total 166 3 282 44 123 122 36 38 4 3 0.504
UNK-BEL 21 145 7 242 34 109 106 24 30 5 2 0.038
Total 2418 94 3937 711 1679 1667 579 602 66 54 0.055

10Q11_21_MG_440  (rs559580)

RUA cohort N N
miss		 Allele
frequencies		 Genotype distribution p-value
T/T T/C C/C
T C O E O E O E
FIN-ATB 21 1037 15 1699 345 704 706 291 287 27 29 0.659
FIN-FIN 03 434 4 719 141 302 301 115 118 13 12 0.606
24 466 5 762 160 314 315 134 132 13 14 0.873
Total 900 9 1481 301 616 615 249 250 26 25 0.907
FRA-PRI 21 170 6 276 52 117 116 42 44 5 4 0.770
SWE-NSW 02 77 0 127 27 54 52 19 22 4 2 0.117
03 89 1 157 19 69 70 19 17 0 1 0.364
Total 166 1 284 46 123 122 38 40 4 3 0.744
UNK-BEL 21 145 3 247 37 109 107 29 32 4 2 0.138
Total 2418 34 3987 781 1669 1667 649 653 66 64 0.769

10Q11_21_MG_443  (rs687175)

RUA cohort N N
miss		 Allele
frequencies		 Genotype distribution p-value
T/T T/C C/C
T C O E O E O E
FIN-ATB 21 1037 10 1707 347 707 709 293 288 27 29 0.658
FIN-FIN 03 434 4 718 142 301 300 116 119 13 12 0.727
24 466 5 762 160 314 315 134 132 13 14 0.872
Total 900 9 1480 302 615 615 250 251 26 26 1.000
FRA-PRI 21 170 3 279 55 117 117 45 46 5 5 0.792
SWE-NSW 02 77 0 127 27 54 52 19 22 4 2 0.115
03 89 1 157 19 69 70 19 17 0 1 0.364
Total 166 1 284 46 123 122 38 40 4 3 0.745
UNK-BEL 21 145 2 248 38 109 108 30 33 4 3 0.472
Total 2418 25 3998 788 1671 1670 656 658 66 65 0.882

10Q11_21_MG_456  (rs513391)

RUA cohort N N
miss		 Allele
frequencies		 Genotype distribution p-value
A/A A/C C/C
A C O E O E O E
FIN-ATB 21 1036 7 1708 350 707 709 294 290 28 30 0.740
FIN-FIN 03 434 5 717 141 301 300 115 118 13 12 0.604
24 466 5 763 159 315 316 133 132 13 14 0.870
Total 900 10 1480 300 616 615 248 249 26 25 0.903
FRA-PRI 21 170 10 268 52 113 112 42 44 5 4 0.771
SWE-NSW 02 77 0 127 27 54 52 19 22 4 2 0.118
03 89 2 155 19 68 69 19 17 0 1 0.363
Total 166 2 282 46 122 121 38 40 4 3 0.746
UNK-BEL 21 145 3 245 39 107 106 31 34 4 3 0.308
Total 2417 32 3983 787 1665 1663 653 657 67 65 0.765

10Q11_21_MG_458  (rs622472)

RUA cohort N N
miss		 Allele
frequencies		 Genotype distribution p-value
A/A A/C C/C
A C O E O E O E
FIN-ATB 21 1036 9 1704 350 705 707 294 290 28 30 0.743
FIN-FIN 03 434 7 711 143 297 296 117 119 13 12 0.736
24 466 7 758 160 313 313 132 132 14 14 1.000
Total 900 14 1469 303 610 609 249 251 27 26 0.815
FRA-PRI 21 170 13 263 51 111 110 41 43 5 4 0.575
SWE-NSW 02 77 4 119 27 50 48 19 22 4 2 0.280
03 89 7 144 20 62 63 20 18 0 1 0.350
Total 166 11 263 47 112 112 39 40 4 4 0.769
UNK-BEL 21 145 3 245 39 107 106 31 34 4 3 0.307
Total 2417 50 3944 790 1645 1643 654 658 68 66 0.767

O:Observed number of the specific genotype
E:Expected number of the specific genotype
npc:Not possible to calculate due to non-occurrence of some alleles
Updated on 2008-12-08