Hardy-Weinberg equilibrium tests in the subcohort for SNPs of the 19Q12 gene:

RUA	cohort	N	N miss	Allele frequencies		Genotype distribution						p-value
				Allele frequencies		G/G		G/C		C/C
				G	C	O	E	O	E	O	E
FIN-ATB	21	1037	10	1505	549	552	551	401	402	74	73	0.936
FIN-FIN	03	434	2	630	234	235	230	160	171	37	32	0.222
	24	466	5	684	238	255	254	174	177	32	31	0.809
	Total	900	7	1314	472	490	483	334	347	69	62	0.263
FRA-PRI	21	170	3	207	127	62	64	83	79	22	24	0.512
SWE-NSW	02	77	0	114	40	41	42	32	30	4	5	0.565
	03	89	1	132	44	47	50	38	33	3	6	0.253
	Total	166	1	246	84	88	92	70	63	7	11	0.155
UNK-BEL	21	145	2	171	115	48	51	75	69	20	23	0.297
Total		2418	23	3443	1347	1240	1237	963	968	192	189	0.804

RUA	cohort	N	N miss	Allele frequencies		Genotype distribution						p-value
				Allele frequencies		G/G		G/A		A/A
				G	A	O	E	O	E	O	E
FIN-ATB	21	1037	30	1752	262	768	762	216	228	23	17	0.125
FIN-FIN	03	434	4	730	130	313	310	104	110	13	10	0.259
	24	466	8	776	140	329	329	118	119	11	11	1.000
	Total	900	12	1506	270	642	639	222	229	24	21	0.434
FRA-PRI	21	170	13	272	42	122	118	28	36	7	3	0.009
SWE-NSW	02	77	2	127	23	53	54	21	19	1	2	0.678
	03	89	2	146	28	61	61	24	23	2	2	1.000
	Total	166	4	273	51	114	115	45	43	3	4	0.576
UNK-BEL	21	145	5	224	56	89	90	46	45	5	6	0.801
Total		2418	64	4027	681	1735	1722	557	582	62	49	0.030

O:	Observed number of the specific genotype
E:	Expected number of the specific genotype
npc:	Not possible to calculate due to non-occurrence of some alleles

Updated on 2008-12-08