Index

Hardy-Weinberg equilibrium tests in the subcohort for SNPs of the 2Q36_3 gene:

  1. 2Q36_3_MG_433 (rs2972147)
  2. 2Q36_3_MG_447 (rs7597168)
  3. 2Q36_3_MG_461 (rs2943634)

2Q36_3_MG_433  (rs2972147)

RUA cohort N N
miss		 Allele
frequencies		 Genotype distribution p-value
C/C C/T T/T
C T O E O E O E
FIN-ATB 21 1037 13 1314 734 423 422 468 471 133 132 0.893
FIN-FIN 03 434 5 534 324 165 166 204 202 60 61 0.839
24 466 5 590 332 191 189 208 212 62 60 0.686
Total 900 10 1124 656 356 355 412 414 122 121 0.886
FRA-PRI 21 170 11 189 129 56 56 77 77 26 26 1.000
SWE-NSW 02 77 3 94 54 32 30 30 34 12 10 0.321
03 89 3 102 70 28 30 46 42 12 14 0.378
Total 166 6 196 124 60 60 76 76 24 24 1.000
UNK-BEL 21 145 8 171 103 55 53 61 64 21 19 0.588
Total 2418 48 2994 1746 950 946 1094 1103 326 322 0.723

2Q36_3_MG_447  (rs7597168)

RUA cohort N N
miss		 Allele
frequencies		 Genotype distribution p-value
C/C C/T T/T
C T O E O E O E
FIN-ATB 21 1037 10 1547 507 581 583 385 382 61 63 0.800
FIN-FIN 03 434 2 640 224 234 237 172 166 26 29 0.458
24 466 6 680 240 253 251 174 177 33 31 0.717
Total 900 8 1320 464 487 488 346 343 59 60 0.862
FRA-PRI 21 170 5 259 71 98 102 63 56 4 8 0.110
SWE-NSW 02 77 0 121 33 48 48 25 26 4 4 0.752
03 89 1 129 47 49 47 31 34 8 6 0.281
Total 166 1 250 80 97 95 56 61 12 10 0.399
UNK-BEL 21 145 2 218 68 82 83 54 52 7 8 0.655
Total 2418 26 3594 1190 1345 1350 904 894 143 148 0.584

2Q36_3_MG_461  (rs2943634)

RUA cohort N N
miss		 Allele
frequencies		 Genotype distribution p-value
C/C C/A A/A
C A O E O E O E
FIN-ATB 21 1037 12 1337 713 436 436 465 465 124 124 1.000
FIN-FIN 03 434 34 504 296 157 159 190 186 53 55 0.749
24 466 16 588 312 197 192 194 204 59 54 0.349
Total 900 50 1092 608 354 351 384 391 112 109 0.654
FRA-PRI 21 190 12 225 131 69 71 87 83 22 24 0.521
SWE-NSW 02 77 0 101 53 36 33 29 35 12 9 0.131
03 89 1 112 64 35 36 42 41 11 12 0.820
Total 166 1 213 117 71 69 71 76 23 21 0.398
UNK-BEL 21 154 6 187 109 61 59 65 69 22 20 0.478
Total 2447 81 3054 1678 991 986 1072 1083 303 298 0.651

O:Observed number of the specific genotype
E:Expected number of the specific genotype
npc:Not possible to calculate due to non-occurrence of some alleles
Updated on 2008-12-08