Index

Hardy-Weinberg equilibrium tests in the subcohort for SNPs of the CELSR2 gene:

  1. CELSR2_MG_434 (rs413380)
  2. CELSR2_MG_438 (rs4970834)

CELSR2_MG_434  (rs413380)

RUA cohort N N
miss		 Allele
frequencies		 Genotype distribution p-value
C/C C/T T/T
C T O E O E O E
FIN-ATB 21 1037 9 1946 110 925 921 96 104 7 3 0.022
FIN-FIN 03 434 2 815 49 384 384 47 46 1 1 1.000
24 466 5 879 43 421 419 37 41 3 1 0.016
Total 900 7 1694 92 805 803 84 87 4 2 0.289
FRA-PRI 21 170 3 320 14 153 153 14 13 0 0 1.000
SWE-NSW 02 77 0 152 2 75 75 2 2 0 0 1.000
03 89 2 170 4 83 83 4 4 0 0 1.000
Total 166 2 322 6 158 158 6 6 0 0 1.000
UNK-BEL 21 145 2 273 13 130 130 13 12 0 0 1.000
Total 2418 23 4555 235 2171 2166 213 223 11 6 0.014

CELSR2_MG_438  (rs4970834)

RUA cohort N N
miss		 Allele
frequencies		 Genotype distribution p-value
C/C C/T T/T
C T O E O E O E
FIN-ATB 21 1037 9 1631 425 644 647 343 337 41 44 0.569
FIN-FIN 03 434 2 683 181 264 270 155 143 13 19 0.084
24 466 6 729 191 287 289 155 151 18 20 0.672
Total 900 8 1412 372 551 559 310 294 31 39 0.130
FRA-PRI 21 170 3 279 55 117 117 45 46 5 5 0.790
SWE-NSW 02 77 1 119 33 50 47 19 26 7 4 0.017
03 89 2 136 38 53 53 30 30 4 4 1.000
Total 166 3 255 71 103 100 49 56 11 8 0.108
UNK-BEL 21 145 2 227 59 91 90 45 47 7 6 0.618
Total 2418 25 3804 982 1506 1512 792 781 95 101 0.493

O:Observed number of the specific genotype
E:Expected number of the specific genotype
npc:Not possible to calculate due to non-occurrence of some alleles
Updated on 2008-12-08