Index

Hardy-Weinberg equilibrium tests in the subcohort for SNPs of the MIA3 gene:

  1. MIA3_MG_430 (rs17465637)
  2. MIA3_MG_454 (rs3008621)

MIA3_MG_430  (rs17465637)

RUA cohort N N
miss		 Allele
frequencies		 Genotype distribution p-value
C/C C/A A/A
C A O E O E O E
FIN-ATB 21 1037 12 1506 544 562 553 382 400 81 72 0.170
FIN-FIN 03 434 5 649 209 239 245 171 158 19 25 0.091
24 466 5 682 240 256 252 170 178 35 31 0.396
Total 900 10 1331 449 495 498 341 336 54 57 0.657
FRA-PRI 21 170 5 245 85 96 91 53 63 16 11 0.042
SWE-NSW 02 77 0 115 39 44 43 27 29 6 5 0.565
03 89 1 133 43 51 50 31 32 6 5 0.572
Total 166 1 248 82 95 93 58 62 12 10 0.532
UNK-BEL 21 145 3 209 75 78 77 53 55 11 10 0.677
Total 2418 31 3539 1235 1326 1312 887 916 174 160 0.124

MIA3_MG_454  (rs3008621)

RUA cohort N N
miss		 Allele
frequencies		 Genotype distribution p-value
G/G G/A A/A
G A O E O E O E
FIN-ATB 21 1036 7 1710 348 716 710 278 289 35 29 0.222
FIN-FIN 03 434 17 719 115 304 310 111 99 2 8 0.023
24 466 5 769 153 324 321 121 128 16 13 0.241
Total 900 22 1488 268 628 630 232 227 18 20 0.602
FRA-PRI 21 170 12 275 41 122 120 31 36 5 3 0.078
SWE-NSW 02 77 0 139 15 64 63 11 14 2 1 0.032
03 89 2 157 17 70 71 17 15 0 1 0.590
Total 166 2 296 32 134 134 28 29 2 2 1.000
UNK-BEL 21 145 3 260 24 118 119 24 22 0 1 0.400
Total 2417 46 4029 713 1718 1712 593 606 60 54 0.298

O:Observed number of the specific genotype
E:Expected number of the specific genotype
npc:Not possible to calculate due to non-occurrence of some alleles
Updated on 2008-12-08