| Rank | SNP name in MORGAM | RS-code | Chromosome | Success | Genotype | Cases | Non-cases | Total | OR (95% CI) | nominal p-value | tail-area FDR |
|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | 9P21_3_MG_425 | rs1333049 | 9 | 99.5% | C/C | 202 (22%) | 356 (17%) | 558 | 1.240 (1.106, 1.389) |
0.00022 | 0.00564 |
| C/G | 425 (46%) | 1042 (49%) | 1467 | ||||||||
| G/G | 287 (31%) | 739 (35%) | 1026 | ||||||||
| 2 | 9P21_3_MG_420 | rs10738610 | 9 | 99.2% | A/A | 282 (31%) | 717 (34%) | 999 | 0.809 (0.722, 0.907) |
0.00027 | 0.00564 |
| A/C | 424 (46%) | 1044 (49%) | 1468 | ||||||||
| C/C | 206 (23%) | 366 (17%) | 572 | ||||||||
| 3 | 10Q11_21_MG_432 | rs2146807 | 10 | 99.3% | C/C | 8 (1%) | 15 (1%) | 23 | 1.357 (1.119, 1.645) |
0.00188 | 0.02629 |
| C/T | 179 (20%) | 352 (17%) | 531 | ||||||||
| T/T | 727 (80%) | 1764 (83%) | 2491 | ||||||||
| 4 | PSRC1_MG_460 | rs599839 | 1 | 99.5% | A/A | 563 (62%) | 1227 (57%) | 1790 | 1.192 (1.041, 1.366) |
0.01131 | 0.11874 |
| A/G | 311 (34%) | 776 (36%) | 1087 | ||||||||
| G/G | 39 (4%) | 133 (6%) | 172 | ||||||||
| 5 | 19Q12_MG_422 | rs11670734 | 19 | 99.5% | C/C | 86 (9%) | 161 (8%) | 247 | 1.165 (1.027, 1.322) |
0.01734 | 0.12423 |
| C/G | 371 (41%) | 873 (41%) | 1244 | ||||||||
| G/G | 457 (50%) | 1102 (52%) | 1559 | ||||||||
| 6 | MIA3_MG_430 | rs17465637 | 1 | 99.1% | A/A | 46 (5%) | 156 (7%) | 202 | 0.852 (0.746, 0.973) |
0.01775 | 0.12423 |
| A/C | 328 (36%) | 782 (37%) | 1110 | ||||||||
| C/C | 534 (59%) | 1191 (56%) | 1725 | ||||||||
| 7 | 9P21_3_MG_421 | rs10757283 | 9 | 99.2% | C/C | 236 (26%) | 628 (29%) | 864 | 0.894 (0.797, 1.003) |
0.05550 | 0.33298 |
| C/T | 469 (51%) | 1068 (50%) | 1537 | ||||||||
| T/T | 207 (23%) | 434 (20%) | 641 | ||||||||
| 8 | SMAD3_MG_424 | rs12913547 | 15 | 99.5% | C/C | 67 (7%) | 154 (7%) | 221 | 1.110 (0.978, 1.261) |
0.10621 | 0.43588 |
| C/T | 400 (44%) | 826 (39%) | 1226 | ||||||||
| T/T | 447 (49%) | 1157 (54%) | 1604 | ||||||||
| 9 | SMAD3_MG_452 | rs17228212 | 15 | 99.1% | C/C | 39 (4%) | 115 (5%) | 154 | 0.894 (0.777, 1.028) |
0.11588 | 0.43588 |
| C/T | 300 (33%) | 769 (36%) | 1069 | ||||||||
| T/T | 570 (63%) | 1245 (58%) | 1815 | ||||||||
| 10 | CELSR2_MG_438 | rs4970834 | 1 | 99.4% | C/C | 597 (65%) | 1331 (62%) | 1928 | 1.119 (0.970, 1.292) |
0.12365 | 0.43588 |
| C/T | 283 (31%) | 715 (34%) | 998 | ||||||||
| T/T | 34 (4%) | 88 (4%) | 122 | ||||||||
| 11 | CELSR2_MG_434 | rs413380 | 1 | 99.5% | C/C | 845 (92%) | 1938 (91%) | 2783 | 1.237 (0.939, 1.629) |
0.12976 | 0.43588 |
| C/T | 66 (7%) | 188 (9%) | 254 | ||||||||
| T/T | 3 (0%) | 10 (0%) | 13 | ||||||||
| 12 | 19Q12_MG_446 | rs7250581 | 19 | 98.0% | A/A | 30 (3%) | 53 (3%) | 83 | 1.127 (0.965, 1.317) |
0.13145 | 0.43588 |
| A/G | 230 (25%) | 495 (24%) | 725 | ||||||||
| G/G | 644 (71%) | 1553 (74%) | 2197 | ||||||||
| 13 | 9P21_3_MG_451 | rs1537378 | 9 | 98.1% | A/A | 131 (15%) | 317 (15%) | 448 | 0.915 (0.813, 1.030) |
0.14253 | 0.43588 |
| A/G | 404 (45%) | 1019 (48%) | 1423 | ||||||||
| G/G | 365 (41%) | 771 (37%) | 1136 | ||||||||
| 14 | 9P21_3_MG_459 | rs7865618 | 9 | 98.8% | A/A | 320 (35%) | 690 (33%) | 1010 | 1.089 (0.971, 1.222) |
0.14529 | 0.43588 |
| A/G | 430 (47%) | 1035 (49%) | 1465 | ||||||||
| G/G | 156 (17%) | 398 (19%) | 554 | ||||||||
| 15 | 9P21_3_MG_437 | rs496892 | 9 | 98.8% | C/C | 250 (28%) | 526 (25%) | 776 | 1.083 (0.965, 1.215) |
0.17465 | 0.48902 |
| C/T | 448 (49%) | 1094 (52%) | 1542 | ||||||||
| T/T | 210 (23%) | 501 (24%) | 711 | ||||||||
| 16 | 12Q12_MG_448 | rs7970834 | 12 | 99.4% | G/G | 276 (30%) | 663 (31%) | 939 | 0.926 (0.824, 1.040) |
0.19298 | 0.50658 |
| G/T | 457 (50%) | 1080 (51%) | 1537 | ||||||||
| T/T | 179 (20%) | 392 (18%) | 571 | ||||||||
| 17 | SEZ6L_MG_442 | rs6005015 | 22 | 99.5% | C/C | 97 (11%) | 195 (9%) | 292 | 1.080 (0.955, 1.221) |
0.21922 | 0.51153 |
| C/T | 385 (42%) | 922 (43%) | 1307 | ||||||||
| T/T | 431 (47%) | 1019 (48%) | 1450 | ||||||||
| 18 | MIA3_MG_454 | rs3008621 | 1 | 98.5% | A/A | 16 (2%) | 53 (3%) | 69 | 0.904 (0.769, 1.062) |
0.21923 | 0.51153 |
| A/G | 224 (25%) | 517 (24%) | 741 | ||||||||
| G/G | 662 (73%) | 1547 (73%) | 2209 | ||||||||
| 19 | SEZ6L_MG_427 | rs137209 | 22 | 99.4% | A/A | 107 (12%) | 213 (10%) | 320 | 1.074 (0.951, 1.214) |
0.24942 | 0.55134 |
| A/G | 412 (45%) | 986 (46%) | 1398 | ||||||||
| G/G | 392 (43%) | 938 (44%) | 1330 | ||||||||
| 20 | SEZ6L_MG_426 | rs137205 | 22 | 99.4% | A/A | 82 (9%) | 165 (8%) | 247 | 1.075 (0.947, 1.219) |
0.26342 | 0.55318 |
| A/G | 395 (43%) | 923 (43%) | 1318 | ||||||||
| G/G | 436 (48%) | 1047 (49%) | 1483 | ||||||||
| 21 | SEZ6L_MG_444 | rs688034 | 22 | 99.4% | C/C | 480 (53%) | 1114 (52%) | 1594 | 0.940 (0.826, 1.070) |
0.34701 | 0.69403 |
| C/T | 362 (40%) | 876 (41%) | 1238 | ||||||||
| T/T | 69 (8%) | 145 (7%) | 214 | ||||||||
| 22 | 10Q11_21_MG_429 | rs1746049 | 10 | 99.5% | C/C | 691 (76%) | 1624 (76%) | 2315 | 0.943 (0.796, 1.117) |
0.49461 | 0.91571 |
| C/T | 209 (23%) | 476 (22%) | 685 | ||||||||
| T/T | 14 (2%) | 36 (2%) | 50 | ||||||||
| 23 | MTHFD1L_MG_449 | rs12214306 | 6 | 99.1% | C/C | 0 (0%) | 1 (0%) | 1 | 1.114 (0.779, 1.593) |
0.55388 | 0.91571 |
| C/T | 49 (5%) | 102 (5%) | 151 | ||||||||
| T/T | 858 (95%) | 2027 (95%) | 2885 | ||||||||
| 24 | FMN2_MG_450 | rs1456648 | 1 | 98.5% | G/G | 28 (3%) | 51 (2%) | 79 | 0.957 (0.819, 1.120) |
0.58522 | 0.91571 |
| G/T | 219 (24%) | 548 (26%) | 767 | ||||||||
| T/T | 655 (73%) | 1518 (72%) | 2173 | ||||||||
| 25 | MTHFD1L_MG_445 | rs6922269 | 6 | 99.3% | A/A | 47 (5%) | 111 (5%) | 158 | 1.039 (0.906, 1.190) |
0.58670 | 0.91571 |
| A/G | 319 (35%) | 753 (35%) | 1072 | ||||||||
| G/G | 546 (60%) | 1267 (59%) | 1813 | ||||||||
| 26 | 5Q21_1_MG_441 | rs565928 | 5 | 99.4% | C/C | 580 (64%) | 1336 (63%) | 1916 | 1.034 (0.904, 1.184) |
0.62407 | 0.91571 |
| C/T | 281 (31%) | 684 (32%) | 965 | ||||||||
| T/T | 51 (6%) | 114 (5%) | 165 | ||||||||
| 27 | 5Q21_1_MG_435 | rs436495 | 5 | 98.9% | A/A | 64 (7%) | 128 (6%) | 192 | 0.969 (0.850, 1.104) |
0.63413 | 0.91571 |
| A/G | 297 (33%) | 743 (35%) | 1040 | ||||||||
| G/G | 550 (60%) | 1249 (59%) | 1799 | ||||||||
| 28 | 5Q21_1_MG_455 | rs383830 | 5 | 99.1% | A/A | 50 (6%) | 113 (5%) | 163 | 0.970 (0.847, 1.111) |
0.66012 | 0.91571 |
| A/T | 281 (31%) | 679 (32%) | 960 | ||||||||
| T/T | 578 (64%) | 1335 (63%) | 1913 | ||||||||
| 29 | 5Q21_1_MG_436 | rs449650 | 5 | 99.1% | G/G | 580 (64%) | 1335 (63%) | 1915 | 1.029 (0.899, 1.177) |
0.67917 | 0.91571 |
| G/T | 281 (31%) | 675 (32%) | 956 | ||||||||
| T/T | 52 (6%) | 115 (5%) | 167 | ||||||||
| 30 | MTHFD1L_MG_423 | rs12525353 | 6 | 99.4% | A/A | 0 (0%) | 2 (0%) | 2 | 0.921 (0.613, 1.383) |
0.69102 | 0.91571 |
| A/C | 35 (4%) | 83 (4%) | 118 | ||||||||
| C/C | 879 (96%) | 2049 (96%) | 2928 | ||||||||
| 31 | SMAD3_MG_431 | rs1866317 | 15 | 99.5% | C/C | 13 (1%) | 34 (2%) | 47 | 1.032 (0.873, 1.220) |
0.70911 | 0.91571 |
| C/G | 226 (25%) | 506 (24%) | 732 | ||||||||
| G/G | 675 (74%) | 1596 (75%) | 2271 | ||||||||
| 32 | 2Q36_3_MG_447 | rs7597168 | 2 | 99.4% | C/C | 518 (57%) | 1195 (56%) | 1713 | 0.976 (0.856, 1.112) |
0.71300 | 0.91571 |
| C/T | 331 (36%) | 815 (38%) | 1146 | ||||||||
| T/T | 65 (7%) | 123 (6%) | 188 | ||||||||
| 33 | 2Q36_3_MG_461 | rs2943634 | 2 | 97.5% | A/A | 114 (13%) | 260 (12%) | 374 | 0.979 (0.869, 1.103) |
0.72321 | 0.91571 |
| A/C | 388 (43%) | 961 (46%) | 1349 | ||||||||
| C/C | 399 (44%) | 866 (41%) | 1265 | ||||||||
| 34 | 10Q11_21_MG_439 | rs501120 | 10 | 96.7% | C/C | 24 (3%) | 55 (3%) | 79 | 1.027 (0.877, 1.203) |
0.74129 | 0.91571 |
| C/T | 224 (25%) | 514 (25%) | 738 | ||||||||
| T/T | 643 (72%) | 1504 (73%) | 2147 | ||||||||
| 35 | 2Q36_3_MG_433 | rs2972147 | 2 | 98.6% | C/C | 374 (41%) | 841 (40%) | 1215 | 0.985 (0.876, 1.108) |
0.80119 | 0.96051 |
| C/T | 402 (44%) | 988 (47%) | 1390 | ||||||||
| T/T | 131 (14%) | 285 (13%) | 416 | ||||||||
| 36 | SEZ6L_MG_457 | rs6005016 | 22 | 99.0% | A/A | 1 (0%) | 4 (0%) | 5 | 0.967 (0.710, 1.316) |
0.83015 | 0.96051 |
| A/G | 59 (6%) | 147 (7%) | 206 | ||||||||
| G/G | 848 (93%) | 1974 (93%) | 2822 | ||||||||
| 37 | 1Q31_2_MG_453 | rs1936982 | 1 | 99.0% | C/C | 111 (12%) | 271 (13%) | 382 | 1.012 (0.899, 1.138) |
0.84616 | 0.96051 |
| C/T | 405 (45%) | 930 (44%) | 1335 | ||||||||
| T/T | 391 (43%) | 926 (44%) | 1317 | ||||||||
| 38 | 10Q11_21_MG_458 | rs622472 | 10 | 98.2% | A/A | 628 (70%) | 1475 (70%) | 2103 | 1.010 (0.865, 1.180) |
0.89665 | 0.96776 |
| A/C | 249 (28%) | 579 (27%) | 828 | ||||||||
| C/C | 22 (2%) | 58 (3%) | 80 | ||||||||
| 39 | 10Q11_21_MG_456 | rs513391 | 10 | 99.1% | A/A | 639 (70%) | 1492 (70%) | 2131 | 1.010 (0.865, 1.179) |
0.89863 | 0.96776 |
| A/C | 248 (27%) | 579 (27%) | 827 | ||||||||
| C/C | 22 (2%) | 57 (3%) | 79 | ||||||||
| 40 | 10Q11_21_MG_440 | rs559580 | 10 | 99.2% | C/C | 23 (3%) | 56 (3%) | 79 | 0.995 (0.853, 1.162) |
0.95413 | 0.97019 |
| C/T | 247 (27%) | 575 (27%) | 822 | ||||||||
| T/T | 643 (70%) | 1495 (70%) | 2138 | ||||||||
| 41 | 10Q11_21_MG_443 | rs687175 | 10 | 99.4% | C/C | 23 (3%) | 56 (3%) | 79 | 0.996 (0.853, 1.162) |
0.95854 | 0.97019 |
| C/T | 248 (27%) | 581 (27%) | 829 | ||||||||
| T/T | 643 (70%) | 1497 (70%) | 2140 | ||||||||
| 42 | 10Q11_21_MG_428 | rs1746048 | 10 | 99.5% | C/C | 643 (70%) | 1501 (70%) | 2144 | 0.997 (0.854, 1.164) |
0.97019 | 0.97019 |
| C/T | 248 (27%) | 579 (27%) | 827 | ||||||||
| T/T | 23 (3%) | 55 (3%) | 78 |
Updated on 2008-12-08
