| Rank | SNP name in MORGAM | RS-code | Chromosome | Success | Genotype | Cases | Non-cases | Total | OR (95% CI) | nominal p-value | tail-area FDR |
|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | 9P21_3_MG_420 | rs10738610 | 9 | 99.1% | A/A | 143 (29%) | 747 (33%) | 890 | 0.801 (0.694, 0.923) |
0.00226 | 0.09486 |
| A/C | 254 (51%) | 1093 (49%) | 1347 | ||||||||
| C/C | 102 (20%) | 397 (18%) | 499 | ||||||||
| 2 | 9P21_3_MG_425 | rs1333049 | 9 | 99.5% | C/C | 100 (20%) | 388 (17%) | 488 | 1.224 (1.062, 1.411) |
0.00529 | 0.11099 |
| C/G | 249 (50%) | 1091 (49%) | 1340 | ||||||||
| G/G | 151 (30%) | 769 (34%) | 920 | ||||||||
| 3 | 1Q31_2_MG_453 | rs1936982 | 1 | 99.1% | C/C | 43 (9%) | 287 (13%) | 330 | 0.840 (0.722, 0.976) |
0.02280 | 0.27729 |
| C/T | 227 (45%) | 980 (44%) | 1207 | ||||||||
| T/T | 231 (46%) | 969 (43%) | 1200 | ||||||||
| 4 | 19Q12_MG_422 | rs11670734 | 19 | 99.5% | C/C | 44 (9%) | 183 (8%) | 227 | 1.191 (1.021, 1.389) |
0.02641 | 0.27729 |
| C/G | 213 (43%) | 907 (40%) | 1120 | ||||||||
| G/G | 243 (49%) | 1157 (51%) | 1400 | ||||||||
| 5 | 9P21_3_MG_451 | rs1537378 | 9 | 98.2% | A/A | 66 (13%) | 329 (15%) | 395 | 0.860 (0.742, 0.996) |
0.04472 | 0.37563 |
| A/G | 224 (45%) | 1075 (49%) | 1299 | ||||||||
| G/G | 210 (42%) | 808 (37%) | 1018 | ||||||||
| 6 | 9P21_3_MG_459 | rs7865618 | 9 | 98.9% | A/A | 179 (36%) | 730 (33%) | 909 | 1.131 (0.981, 1.303) |
0.09058 | 0.55632 |
| A/G | 241 (48%) | 1085 (49%) | 1326 | ||||||||
| G/G | 81 (16%) | 415 (19%) | 496 | ||||||||
| 7 | PSRC1_MG_460 | rs599839 | 1 | 99.5% | A/A | 306 (61%) | 1305 (58%) | 1611 | 1.156 (0.976, 1.370) |
0.09272 | 0.55632 |
| A/G | 178 (36%) | 802 (36%) | 980 | ||||||||
| G/G | 17 (3%) | 139 (6%) | 156 | ||||||||
| 8 | 9P21_3_MG_437 | rs496892 | 9 | 98.9% | C/C | 139 (28%) | 564 (25%) | 703 | 1.097 (0.952, 1.264) |
0.19984 | 0.87724 |
| C/T | 243 (49%) | 1141 (51%) | 1384 | ||||||||
| T/T | 115 (23%) | 528 (24%) | 643 | ||||||||
| 9 | SMAD3_MG_431 | rs1866317 | 15 | 99.5% | C/C | 12 (2%) | 35 (2%) | 47 | 1.135 (0.928, 1.389) |
0.21852 | 0.87724 |
| C/G | 123 (25%) | 531 (24%) | 654 | ||||||||
| G/G | 365 (73%) | 1681 (75%) | 2046 | ||||||||
| 10 | FMN2_MG_450 | rs1456648 | 1 | 98.8% | G/G | 9 (2%) | 56 (3%) | 65 | 0.884 (0.725, 1.077) |
0.21989 | 0.87724 |
| G/T | 129 (26%) | 576 (26%) | 705 | ||||||||
| T/T | 363 (72%) | 1594 (72%) | 1957 | ||||||||
| 11 | 19Q12_MG_446 | rs7250581 | 19 | 97.9% | A/A | 14 (3%) | 60 (3%) | 74 | 1.125 (0.928, 1.363) |
0.22975 | 0.87724 |
| A/G | 128 (26%) | 523 (24%) | 651 | ||||||||
| G/G | 352 (71%) | 1627 (74%) | 1979 | ||||||||
| 12 | SMAD3_MG_452 | rs17228212 | 15 | 99.2% | C/C | 16 (3%) | 118 (5%) | 134 | 0.905 (0.760, 1.078) |
0.26258 | 0.89063 |
| C/T | 177 (35%) | 807 (36%) | 984 | ||||||||
| T/T | 308 (61%) | 1313 (59%) | 1621 | ||||||||
| 13 | MTHFD1L_MG_423 | rs12525353 | 6 | 99.4% | A/A | 0 (0%) | 2 (0%) | 2 | 0.726 (0.409, 1.290) |
0.27567 | 0.89063 |
| A/C | 14 (3%) | 85 (4%) | 99 | ||||||||
| C/C | 486 (97%) | 2158 (96%) | 2644 | ||||||||
| 14 | 2Q36_3_MG_447 | rs7597168 | 2 | 99.4% | C/C | 297 (59%) | 1256 (56%) | 1553 | 1.086 (0.923, 1.278) |
0.31901 | 0.89234 |
| C/T | 165 (33%) | 857 (38%) | 1022 | ||||||||
| T/T | 38 (8%) | 131 (6%) | 169 | ||||||||
| 15 | SEZ6L_MG_427 | rs137209 | 22 | 99.3% | A/A | 49 (10%) | 227 (10%) | 276 | 0.934 (0.800, 1.089) |
0.38161 | 0.89234 |
| A/G | 211 (43%) | 1041 (46%) | 1252 | ||||||||
| G/G | 236 (48%) | 979 (44%) | 1215 | ||||||||
| 16 | 2Q36_3_MG_461 | rs2943634 | 2 | 97.2% | A/A | 62 (13%) | 279 (13%) | 341 | 0.945 (0.815, 1.095) |
0.45094 | 0.89234 |
| A/C | 210 (43%) | 990 (45%) | 1200 | ||||||||
| C/C | 221 (45%) | 923 (42%) | 1144 | ||||||||
| 17 | MIA3_MG_430 | rs17465637 | 1 | 99.1% | A/A | 32 (6%) | 161 (7%) | 193 | 0.942 (0.801, 1.107) |
0.46699 | 0.89234 |
| A/C | 179 (36%) | 836 (37%) | 1015 | ||||||||
| C/C | 287 (58%) | 1242 (55%) | 1529 | ||||||||
| 18 | 12Q12_MG_448 | rs7970834 | 12 | 99.4% | G/G | 161 (32%) | 692 (31%) | 853 | 0.948 (0.821, 1.095) |
0.46898 | 0.89234 |
| G/T | 236 (47%) | 1143 (51%) | 1379 | ||||||||
| T/T | 102 (20%) | 411 (18%) | 513 | ||||||||
| 19 | 5Q21_1_MG_435 | rs436495 | 5 | 98.8% | A/A | 31 (6%) | 138 (6%) | 169 | 1.059 (0.902, 1.243) |
0.48699 | 0.89234 |
| A/G | 188 (38%) | 776 (35%) | 964 | ||||||||
| G/G | 277 (56%) | 1317 (59%) | 1594 | ||||||||
| 20 | CELSR2_MG_438 | rs4970834 | 1 | 99.4% | C/C | 322 (65%) | 1411 (63%) | 1733 | 1.064 (0.891, 1.270) |
0.49578 | 0.89234 |
| C/T | 158 (32%) | 742 (33%) | 900 | ||||||||
| T/T | 19 (4%) | 92 (4%) | 111 | ||||||||
| 21 | 10Q11_21_MG_429 | rs1746049 | 10 | 99.5% | C/C | 390 (78%) | 1698 (76%) | 2088 | 1.074 (0.866, 1.332) |
0.51424 | 0.89234 |
| C/T | 101 (20%) | 512 (23%) | 613 | ||||||||
| T/T | 9 (2%) | 37 (2%) | 46 | ||||||||
| 22 | SEZ6L_MG_444 | rs688034 | 22 | 99.4% | C/C | 280 (56%) | 1166 (52%) | 1446 | 1.052 (0.894, 1.238) |
0.54327 | 0.89234 |
| C/T | 186 (37%) | 921 (41%) | 1107 | ||||||||
| T/T | 33 (7%) | 158 (7%) | 191 | ||||||||
| 23 | 2Q36_3_MG_433 | rs2972147 | 2 | 98.6% | C/C | 210 (42%) | 896 (40%) | 1106 | 1.044 (0.902, 1.207) |
0.56441 | 0.89234 |
| C/T | 220 (44%) | 1019 (46%) | 1239 | ||||||||
| T/T | 69 (14%) | 309 (14%) | 378 | ||||||||
| 24 | 5Q21_1_MG_455 | rs383830 | 5 | 99.1% | A/A | 26 (5%) | 122 (5%) | 148 | 1.049 (0.889, 1.236) |
0.57283 | 0.89234 |
| A/T | 172 (34%) | 705 (32%) | 877 | ||||||||
| T/T | 302 (60%) | 1409 (63%) | 1711 | ||||||||
| 25 | 10Q11_21_MG_432 | rs2146807 | 10 | 99.3% | C/C | 5 (1%) | 17 (1%) | 22 | 1.072 (0.837, 1.372) |
0.58129 | 0.89234 |
| C/T | 80 (16%) | 381 (17%) | 461 | ||||||||
| T/T | 415 (83%) | 1844 (82%) | 2259 | ||||||||
| 26 | 9P21_3_MG_421 | rs10757283 | 9 | 99.2% | C/C | 147 (30%) | 653 (29%) | 800 | 1.040 (0.902, 1.199) |
0.58741 | 0.89234 |
| C/T | 246 (49%) | 1120 (50%) | 1366 | ||||||||
| T/T | 105 (21%) | 468 (21%) | 573 | ||||||||
| 27 | SEZ6L_MG_457 | rs6005016 | 22 | 99.1% | A/A | 0 (0%) | 4 (0%) | 4 | 1.110 (0.758, 1.627) |
0.59170 | 0.89234 |
| A/G | 35 (7%) | 151 (7%) | 186 | ||||||||
| G/G | 466 (93%) | 2079 (93%) | 2545 | ||||||||
| 28 | SEZ6L_MG_426 | rs137205 | 22 | 99.4% | A/A | 36 (7%) | 177 (8%) | 213 | 0.959 (0.819, 1.124) |
0.60496 | 0.89234 |
| A/G | 209 (42%) | 970 (43%) | 1179 | ||||||||
| G/G | 254 (51%) | 1099 (49%) | 1353 | ||||||||
| 29 | 5Q21_1_MG_441 | rs565928 | 5 | 99.4% | C/C | 302 (61%) | 1410 (63%) | 1712 | 0.967 (0.820, 1.141) |
0.69240 | 0.89234 |
| C/T | 172 (34%) | 711 (32%) | 883 | ||||||||
| T/T | 25 (5%) | 124 (6%) | 149 | ||||||||
| 30 | 10Q11_21_MG_458 | rs622472 | 10 | 98.4% | A/A | 351 (71%) | 1541 (69%) | 1892 | 1.037 (0.857, 1.255) |
0.71024 | 0.89234 |
| A/C | 131 (26%) | 617 (28%) | 748 | ||||||||
| C/C | 15 (3%) | 61 (3%) | 76 | ||||||||
| 31 | 5Q21_1_MG_436 | rs449650 | 5 | 99.1% | G/G | 303 (61%) | 1408 (63%) | 1711 | 0.972 (0.824, 1.146) |
0.73189 | 0.89234 |
| G/T | 172 (34%) | 702 (31%) | 874 | ||||||||
| T/T | 25 (5%) | 125 (6%) | 150 | ||||||||
| 32 | 10Q11_21_MG_439 | rs501120 | 10 | 96.6% | C/C | 15 (3%) | 59 (3%) | 74 | 0.970 (0.797, 1.181) |
0.76261 | 0.89234 |
| C/T | 115 (24%) | 545 (25%) | 660 | ||||||||
| T/T | 356 (73%) | 1576 (72%) | 1932 | ||||||||
| 33 | 10Q11_21_MG_443 | rs687175 | 10 | 99.4% | C/C | 15 (3%) | 59 (3%) | 74 | 0.971 (0.802, 1.176) |
0.76697 | 0.89234 |
| C/T | 130 (26%) | 618 (28%) | 748 | ||||||||
| T/T | 354 (71%) | 1568 (70%) | 1922 | ||||||||
| 34 | SEZ6L_MG_442 | rs6005015 | 22 | 99.5% | C/C | 41 (8%) | 207 (9%) | 248 | 0.977 (0.836, 1.142) |
0.77167 | 0.89234 |
| C/T | 209 (42%) | 963 (43%) | 1172 | ||||||||
| T/T | 250 (50%) | 1076 (48%) | 1326 | ||||||||
| 35 | 10Q11_21_MG_456 | rs513391 | 10 | 99.2% | A/A | 355 (71%) | 1561 (70%) | 1916 | 1.028 (0.850, 1.244) |
0.77461 | 0.89234 |
| A/C | 131 (26%) | 616 (28%) | 747 | ||||||||
| C/C | 15 (3%) | 60 (3%) | 75 | ||||||||
| 36 | 10Q11_21_MG_440 | rs559580 | 10 | 99.1% | C/C | 15 (3%) | 59 (3%) | 74 | 0.973 (0.804, 1.178) |
0.78088 | 0.89234 |
| C/T | 130 (26%) | 611 (27%) | 741 | ||||||||
| T/T | 355 (71%) | 1566 (70%) | 1921 | ||||||||
| 37 | MTHFD1L_MG_445 | rs6922269 | 6 | 99.2% | A/A | 20 (4%) | 122 (5%) | 142 | 0.977 (0.824, 1.159) |
0.79056 | 0.89234 |
| A/G | 180 (36%) | 786 (35%) | 966 | ||||||||
| G/G | 298 (60%) | 1334 (60%) | 1632 | ||||||||
| 38 | 10Q11_21_MG_428 | rs1746048 | 10 | 99.5% | C/C | 355 (71%) | 1572 (70%) | 1927 | 1.024 (0.846, 1.240) |
0.80736 | 0.89234 |
| C/T | 130 (26%) | 616 (27%) | 746 | ||||||||
| T/T | 15 (3%) | 58 (3%) | 73 | ||||||||
| 39 | SMAD3_MG_424 | rs12913547 | 15 | 99.5% | C/C | 37 (7%) | 158 (7%) | 195 | 1.017 (0.868, 1.191) |
0.83924 | 0.90379 |
| C/T | 202 (40%) | 891 (40%) | 1093 | ||||||||
| T/T | 261 (52%) | 1199 (53%) | 1460 | ||||||||
| 40 | CELSR2_MG_434 | rs413380 | 1 | 99.5% | C/C | 454 (91%) | 2045 (91%) | 2499 | 0.978 (0.710, 1.347) |
0.89087 | 0.93541 |
| C/T | 44 (9%) | 192 (9%) | 236 | ||||||||
| T/T | 2 (0%) | 10 (0%) | 12 | ||||||||
| 41 | MTHFD1L_MG_449 | rs12214306 | 6 | 99.2% | C/C | 0 (0%) | 1 (0%) | 1 | 0.985 (0.628, 1.544) |
0.94776 | 0.97087 |
| C/T | 25 (5%) | 115 (5%) | 140 | ||||||||
| T/T | 476 (95%) | 2123 (95%) | 2599 | ||||||||
| 42 | MIA3_MG_454 | rs3008621 | 1 | 98.7% | A/A | 10 (2%) | 57 (3%) | 67 | 0.998 (0.821, 1.212) |
0.98345 | 0.98345 |
| A/G | 133 (27%) | 548 (25%) | 681 | ||||||||
| G/G | 357 (71%) | 1619 (73%) | 1976 |
Updated on 2008-12-08
