Linear regression for BMI, test for additive allele effects, subcohort

Rank SNP name in MORGAM RS-code Chromosome Success Genotype N Mean coef (95% CI) nominal p-value tail-area FDR
1 10Q11_21_MG_429 rs1746049 10 99.5% C/C 1575 27.108 0.395
(0.018, 0.772)		 0.03981 0.63513
C/T 463 26.638
T/T 34 26.466
2 2Q36_3_MG_447 rs7597168 2 99.3% C/C 1158 27.132 0.264
(-0.031, 0.560)		 0.07981 0.63513
C/T 793 26.761
T/T 118 27.043
3 10Q11_21_MG_432 rs2146807 10 99.2% C/C 15 26.341 -0.380
(-0.826, 0.065)		 0.09427 0.63513
C/T 342 26.568
T/T 1710 27.088
4 MTHFD1L_MG_423 rs12525353 6 99.4% A/A 2 26.585 -0.736
(-1.623, 0.150)		 0.10360 0.63513
A/C 79 26.277
C/C 1989 27.018
5 SEZ6L_MG_426 rs137205 22 99.4% A/A 160 26.540 -0.200
(-0.484, 0.084)		 0.16688 0.63513
A/G 897 26.894
G/G 1014 27.149
6 SEZ6L_MG_427 rs137209 22 99.5% A/A 208 26.625 -0.193
(-0.467, 0.081)		 0.16833 0.63513
A/G 958 26.912
G/G 907 27.160
7 10Q11_21_MG_428 rs1746048 10 99.4% C/C 1456 27.053 0.232
(-0.111, 0.576)		 0.18451 0.63513
C/T 563 26.856
T/T 52 26.524
8 2Q36_3_MG_433 rs2972147 2 98.5% C/C 822 26.955 -0.168
(-0.432, 0.095)		 0.20998 0.63513
C/T 951 26.881
T/T 278 27.493
9 5Q21_1_MG_441 rs565928 5 99.4% C/C 1301 26.909 -0.188
(-0.490, 0.114)		 0.22262 0.63513
C/T 661 27.112
T/T 109 27.260
10 5Q21_1_MG_455 rs383830 5 99.0% A/A 108 27.226 0.180
(-0.124, 0.483)		 0.24593 0.63513
A/T 655 27.120
T/T 1300 26.916
11 5Q21_1_MG_436 rs449650 5 98.9% G/G 1299 26.914 -0.179
(-0.482, 0.124)		 0.24641 0.63513
G/T 652 27.115
T/T 110 27.242
12 10Q11_21_MG_458 rs622472 10 98.3% A/A 1430 27.056 0.202
(-0.142, 0.545)		 0.24965 0.63513
A/C 563 26.817
C/C 55 26.863
13 MTHFD1L_MG_445 rs6922269 6 99.3% A/A 110 27.246 -0.172
(-0.473, 0.129)		 0.26389 0.63513
A/G 724 26.666
G/G 1234 27.156
14 2Q36_3_MG_461 rs2943634 2 97.2% A/A 254 27.559 0.149
(-0.118, 0.416)		 0.27387 0.63513
A/C 926 26.800
C/C 845 26.969
15 9P21_3_MG_459 rs7865618 9 98.8% A/A 669 26.904 -0.143
(-0.398, 0.113)		 0.27458 0.63513
A/G 1008 26.982
G/G 382 27.182
16 10Q11_21_MG_443 rs687175 10 99.4% C/C 53 26.757 -0.189
(-0.529, 0.152)		 0.27714 0.63513
C/T 565 26.850
T/T 1452 27.039
17 10Q11_21_MG_440 rs559580 10 99.0% C/C 53 26.757 -0.191
(-0.535, 0.154)		 0.27795 0.63513
C/T 559 26.868
T/T 1450 27.054
18 10Q11_21_MG_439 rs501120 10 96.6% C/C 52 26.803 -0.193
(-0.547, 0.162)		 0.28765 0.63513
C/T 501 26.862
T/T 1459 27.051
19 10Q11_21_MG_456 rs513391 10 99.1% A/A 1447 27.058 0.185
(-0.158, 0.528)		 0.28999 0.63513
A/C 563 26.830
C/C 54 26.889
20 9P21_3_MG_451 rs1537378 9 98.1% A/A 305 27.206 0.138
(-0.125, 0.401)		 0.30244 0.63513
A/G 991 26.944
G/G 747 26.933
21 9P21_3_MG_425 rs1333049 9 99.5% C/C 349 27.014 -0.130
(-0.389, 0.128)		 0.32241 0.64482
C/G 1011 26.770
G/G 713 27.296
22 5Q21_1_MG_435 rs436495 5 98.8% A/A 122 27.185 0.142
(-0.151, 0.436)		 0.34210 0.65310
A/G 718 27.100
G/G 1217 26.905
23 SEZ6L_MG_442 rs6005015 22 99.5% C/C 186 26.800 -0.116
(-0.393, 0.161)		 0.41123 0.75094
C/T 895 26.902
T/T 991 27.097
24 9P21_3_MG_420 rs10738610 9 99.1% A/A 694 27.275 0.101
(-0.158, 0.359)		 0.44576 0.78009
A/C 1011 26.796
C/C 359 27.015
25 19Q12_MG_446 rs7250581 19 97.9% A/A 52 26.974 -0.133
(-0.493, 0.226)		 0.46691 0.78011
A/G 477 26.873
G/G 1511 27.032
26 SEZ6L_MG_444 rs688034 22 99.4% C/C 1077 27.103 0.103
(-0.188, 0.394)		 0.48683 0.78011
C/T 853 26.929
T/T 141 26.529
27 9P21_3_MG_421 rs10757283 9 99.2% C/C 607 26.957 -0.086
(-0.340, 0.169)		 0.50882 0.78011
C/T 1038 26.909
T/T 422 27.203
28 SEZ6L_MG_457 rs6005016 22 98.9% A/A 4 26.360 -0.220
(-0.892, 0.451)		 0.52008 0.78011
A/G 143 26.676
G/G 1914 27.020
29 CELSR2_MG_438 rs4970834 1 99.4% C/C 1295 26.996 0.088
(-0.225, 0.401)		 0.57980 0.83971
C/T 689 27.063
T/T 86 26.347
30 1Q31_2_MG_453 rs1936982 1 99.0% C/C 265 27.084 0.061
(-0.200, 0.322)		 0.64800 0.90720
C/T 901 27.022
T/T 897 26.935
31 SMAD3_MG_424 rs12913547 15 99.5% C/C 145 27.064 0.053
(-0.234, 0.340)		 0.71703 0.97146
C/T 808 27.079
T/T 1120 26.920
32 PSRC1_MG_460 rs599839 1 99.5% A/A 1195 26.956 -0.047
(-0.337, 0.244)		 0.75205 0.98707
A/G 747 27.073
G/G 130 26.788
33 SMAD3_MG_452 rs17228212 15 99.1% C/C 110 26.821 -0.031
(-0.335, 0.273)		 0.84255 0.98915
C/T 747 26.917
T/T 1208 27.052
34 SMAD3_MG_431 rs1866317 15 99.5% C/C 32 27.696 -0.028
(-0.404, 0.348)		 0.88220 0.98915
C/G 489 26.878
G/G 1551 27.015
35 9P21_3_MG_437 rs496892 9 98.8% C/C 513 26.970 0.019
(-0.238, 0.276)		 0.88581 0.98915
C/T 1065 27.021
T/T 481 26.957
36 MIA3_MG_454 rs3008621 1 98.6% A/A 53 27.265 0.025
(-0.330, 0.380)		 0.88945 0.98915
A/G 496 26.992
G/G 1504 26.976
37 12Q12_MG_448 rs7970834 12 99.4% G/G 644 27.138 0.017
(-0.243, 0.276)		 0.89980 0.98915
G/T 1048 26.831
T/T 379 27.170
38 MIA3_MG_430 rs17465637 1 99.1% A/A 151 26.936 -0.015
(-0.297, 0.266)		 0.91453 0.98915
A/C 761 26.937
C/C 1153 27.006
39 19Q12_MG_422 rs11670734 19 99.5% C/C 157 27.194 -0.008
(-0.293, 0.278)		 0.95791 0.98915
C/G 843 26.852
G/G 1072 27.071
40 MTHFD1L_MG_449 rs12214306 6 99.2% C/C 1 37.990 0.020
(-0.813, 0.853)		 0.96262 0.98915
C/T 96 26.726
T/T 1969 27.001
41 CELSR2_MG_434 rs413380 1 99.5% C/C 1882 26.987 -0.006
(-0.579, 0.568)		 0.98493 0.98915
C/T 180 27.097
T/T 10 26.146
42 FMN2_MG_450 rs1456648 1 98.6% G/G 49 27.162 0.002
(-0.348, 0.353)		 0.98915 0.98915
G/T 530 27.008
T/T 1474 26.969

adjusted for: cohort age1 sex

Updated on 2008-12-08