| Rank | SNP name in MORGAM | RS-code | Chromosome | Success | Genotype | Cases | Non-cases | Total | OR (95% CI) | nominal p-value | tail-area FDR |
|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | 9P21_3_MG_425 | rs1333049 | 9 | 99.6% | C/C | 298 (22%) | 288 (17%) | 586 | 1.268 (1.142, 1.408) |
<0.00001 | <0.00001 |
| C/G | 649 (49%) | 846 (49%) | 1495 | ||||||||
| G/G | 384 (29%) | 586 (34%) | 970 | ||||||||
| 2 | 9P21_3_MG_420 | rs10738610 | 9 | 99.1% | A/A | 379 (29%) | 566 (33%) | 945 | 0.800 (0.720, 0.888) |
0.00003 | 0.00064 |
| A/C | 644 (49%) | 847 (50%) | 1491 | ||||||||
| C/C | 303 (23%) | 297 (17%) | 600 | ||||||||
| 3 | PSRC1_MG_460 | rs599839 | 1 | 99.2% | A/A | 813 (61%) | 991 (58%) | 1804 | 1.142 (1.010, 1.290) |
0.03401 | 0.42183 |
| A/G | 448 (34%) | 617 (36%) | 1065 | ||||||||
| G/G | 63 (5%) | 108 (6%) | 171 | ||||||||
| 4 | 10Q11_21_MG_432 | rs2146807 | 10 | 99.4% | C/C | 15 (1%) | 14 (1%) | 29 | 1.200 (1.008, 1.427) |
0.04017 | 0.42183 |
| C/T | 253 (19%) | 289 (17%) | 542 | ||||||||
| T/T | 1063 (80%) | 1413 (82%) | 2476 | ||||||||
| 5 | MIA3_MG_454 | rs3008621 | 1 | 98.6% | A/A | 26 (2%) | 42 (2%) | 68 | 0.870 (0.749, 1.009) |
0.06571 | 0.44608 |
| A/G | 298 (23%) | 422 (25%) | 720 | ||||||||
| G/G | 999 (76%) | 1233 (73%) | 2232 | ||||||||
| 6 | 9P21_3_MG_437 | rs496892 | 9 | 98.9% | C/C | 379 (29%) | 432 (25%) | 811 | 1.102 (0.993, 1.223) |
0.06801 | 0.44608 |
| C/T | 650 (49%) | 880 (52%) | 1530 | ||||||||
| T/T | 294 (22%) | 395 (23%) | 689 | ||||||||
| 7 | SMAD3_MG_452 | rs17228212 | 15 | 99.1% | C/C | 65 (5%) | 94 (6%) | 159 | 0.896 (0.790, 1.015) |
0.08496 | 0.44608 |
| C/T | 458 (35%) | 627 (37%) | 1085 | ||||||||
| T/T | 804 (61%) | 988 (58%) | 1792 | ||||||||
| 8 | MIA3_MG_430 | rs17465637 | 1 | 99.2% | A/A | 79 (6%) | 125 (7%) | 204 | 0.902 (0.801, 1.015) |
0.08761 | 0.44608 |
| A/C | 479 (36%) | 644 (38%) | 1123 | ||||||||
| C/C | 766 (58%) | 945 (55%) | 1711 | ||||||||
| 9 | 9P21_3_MG_459 | rs7865618 | 9 | 98.8% | A/A | 465 (35%) | 568 (33%) | 1033 | 1.094 (0.984, 1.216) |
0.09559 | 0.44608 |
| A/G | 654 (49%) | 823 (48%) | 1477 | ||||||||
| G/G | 205 (15%) | 312 (18%) | 517 | ||||||||
| 10 | CELSR2_MG_434 | rs413380 | 1 | 99.5% | C/C | 1233 (93%) | 1560 (91%) | 2793 | 1.214 (0.945, 1.558) |
0.12853 | 0.52392 |
| C/T | 93 (7%) | 152 (9%) | 245 | ||||||||
| T/T | 5 (0%) | 7 (0%) | 12 | ||||||||
| 11 | 9P21_3_MG_421 | rs10757283 | 9 | 99.3% | C/C | 346 (26%) | 504 (29%) | 850 | 0.923 (0.831, 1.026) |
0.13722 | 0.52392 |
| C/T | 700 (53%) | 855 (50%) | 1555 | ||||||||
| T/T | 283 (21%) | 355 (21%) | 638 | ||||||||
| 12 | 9P21_3_MG_451 | rs1537378 | 9 | 98.1% | A/A | 166 (13%) | 252 (15%) | 418 | 0.924 (0.829, 1.029) |
0.14970 | 0.52396 |
| A/G | 633 (48%) | 798 (47%) | 1431 | ||||||||
| G/G | 519 (39%) | 639 (38%) | 1158 | ||||||||
| 13 | SMAD3_MG_431 | rs1866317 | 15 | 99.5% | C/C | 28 (2%) | 24 (1%) | 52 | 1.109 (0.952, 1.291) |
0.18374 | 0.57405 |
| C/G | 308 (23%) | 395 (23%) | 703 | ||||||||
| G/G | 995 (75%) | 1300 (76%) | 2295 | ||||||||
| 14 | 19Q12_MG_446 | rs7250581 | 19 | 98.2% | A/A | 37 (3%) | 44 (3%) | 81 | 1.100 (0.954, 1.268) |
0.19135 | 0.57405 |
| A/G | 342 (26%) | 399 (24%) | 741 | ||||||||
| G/G | 940 (71%) | 1246 (74%) | 2186 | ||||||||
| 15 | SMAD3_MG_424 | rs12913547 | 15 | 99.6% | C/C | 92 (7%) | 129 (8%) | 221 | 1.063 (0.946, 1.194) |
0.30620 | 0.77268 |
| C/T | 558 (42%) | 657 (38%) | 1215 | ||||||||
| T/T | 681 (51%) | 934 (54%) | 1615 | ||||||||
| 16 | 5Q21_1_MG_441 | rs565928 | 5 | 99.5% | C/C | 858 (64%) | 1084 (63%) | 1942 | 1.066 (0.941, 1.207) |
0.31556 | 0.77268 |
| C/T | 410 (31%) | 541 (32%) | 951 | ||||||||
| T/T | 63 (5%) | 92 (5%) | 155 | ||||||||
| 17 | MTHFD1L_MG_423 | rs12525353 | 6 | 99.5% | A/A | 0 (0%) | 2 (0%) | 2 | 0.828 (0.571, 1.203) |
0.32230 | 0.77268 |
| A/C | 48 (4%) | 69 (4%) | 117 | ||||||||
| C/C | 1282 (96%) | 1647 (96%) | 2929 | ||||||||
| 18 | 5Q21_1_MG_455 | rs383830 | 5 | 99.1% | A/A | 61 (5%) | 91 (5%) | 152 | 0.940 (0.829, 1.065) |
0.33115 | 0.77268 |
| A/T | 409 (31%) | 536 (31%) | 945 | ||||||||
| T/T | 858 (65%) | 1080 (63%) | 1938 | ||||||||
| 19 | 5Q21_1_MG_435 | rs436495 | 5 | 98.8% | A/A | 76 (6%) | 103 (6%) | 179 | 0.946 (0.838, 1.068) |
0.36780 | 0.77775 |
| A/G | 442 (33%) | 593 (35%) | 1035 | ||||||||
| G/G | 805 (61%) | 1009 (59%) | 1814 | ||||||||
| 20 | 5Q21_1_MG_436 | rs449650 | 5 | 99.2% | G/G | 858 (65%) | 1085 (63%) | 1943 | 1.058 (0.934, 1.198) |
0.37696 | 0.77775 |
| G/T | 409 (31%) | 532 (31%) | 941 | ||||||||
| T/T | 63 (5%) | 93 (5%) | 156 | ||||||||
| 21 | FMN2_MG_450 | rs1456648 | 1 | 98.6% | G/G | 37 (3%) | 44 (3%) | 81 | 0.939 (0.814, 1.083) |
0.38992 | 0.77775 |
| G/T | 322 (24%) | 448 (26%) | 770 | ||||||||
| T/T | 963 (73%) | 1207 (71%) | 2170 | ||||||||
| 22 | CELSR2_MG_438 | rs4970834 | 1 | 99.4% | C/C | 853 (64%) | 1079 (63%) | 1932 | 1.056 (0.928, 1.203) |
0.40739 | 0.77775 |
| C/T | 430 (32%) | 567 (33%) | 997 | ||||||||
| T/T | 46 (3%) | 71 (4%) | 117 | ||||||||
| 23 | 2Q36_3_MG_461 | rs2943634 | 2 | 97.0% | A/A | 161 (12%) | 211 (13%) | 372 | 0.957 (0.859, 1.067) |
0.43305 | 0.79079 |
| A/C | 564 (44%) | 766 (46%) | 1330 | ||||||||
| C/C | 569 (44%) | 702 (42%) | 1271 | ||||||||
| 24 | SEZ6L_MG_426 | rs137205 | 22 | 99.5% | A/A | 112 (8%) | 139 (8%) | 251 | 0.960 (0.857, 1.077) |
0.48977 | 0.80760 |
| A/G | 555 (42%) | 748 (44%) | 1303 | ||||||||
| G/G | 664 (50%) | 831 (48%) | 1495 | ||||||||
| 25 | 12Q12_MG_448 | rs7970834 | 12 | 99.4% | G/G | 403 (30%) | 543 (32%) | 946 | 0.964 (0.867, 1.071) |
0.49395 | 0.80760 |
| G/T | 681 (51%) | 860 (50%) | 1541 | ||||||||
| T/T | 243 (18%) | 316 (18%) | 559 | ||||||||
| 26 | 10Q11_21_MG_439 | rs501120 | 10 | 97.1% | C/C | 36 (3%) | 43 (3%) | 79 | 1.051 (0.910, 1.213) |
0.49994 | 0.80760 |
| C/T | 330 (25%) | 414 (25%) | 744 | ||||||||
| T/T | 941 (72%) | 1212 (73%) | 2153 | ||||||||
| 27 | 10Q11_21_MG_429 | rs1746049 | 10 | 99.5% | C/C | 1010 (76%) | 1304 (76%) | 2314 | 0.966 (0.828, 1.126) |
0.65495 | 0.96726 |
| C/T | 296 (22%) | 387 (23%) | 683 | ||||||||
| T/T | 24 (2%) | 28 (2%) | 52 | ||||||||
| 28 | MTHFD1L_MG_445 | rs6922269 | 6 | 99.2% | A/A | 67 (5%) | 89 (5%) | 156 | 1.025 (0.906, 1.160) |
0.69093 | 0.96726 |
| A/G | 483 (36%) | 615 (36%) | 1098 | ||||||||
| G/G | 777 (59%) | 1010 (59%) | 1787 | ||||||||
| 29 | SEZ6L_MG_444 | rs688034 | 22 | 99.4% | C/C | 706 (53%) | 887 (52%) | 1593 | 1.023 (0.911, 1.149) |
0.70046 | 0.96726 |
| C/T | 518 (39%) | 705 (41%) | 1223 | ||||||||
| T/T | 105 (8%) | 126 (7%) | 231 | ||||||||
| 30 | SEZ6L_MG_442 | rs6005015 | 22 | 99.5% | C/C | 131 (10%) | 161 (9%) | 292 | 0.979 (0.876, 1.095) |
0.70841 | 0.96726 |
| C/T | 555 (42%) | 742 (43%) | 1297 | ||||||||
| T/T | 644 (48%) | 816 (47%) | 1460 | ||||||||
| 31 | 19Q12_MG_422 | rs11670734 | 19 | 99.5% | C/C | 117 (9%) | 144 (8%) | 261 | 1.021 (0.911, 1.144) |
0.71952 | 0.96726 |
| C/G | 533 (40%) | 700 (41%) | 1233 | ||||||||
| G/G | 681 (51%) | 875 (51%) | 1556 | ||||||||
| 32 | SEZ6L_MG_457 | rs6005016 | 22 | 99.0% | A/A | 2 (0%) | 3 (0%) | 5 | 0.957 (0.727, 1.261) |
0.75581 | 0.96726 |
| A/G | 91 (7%) | 120 (7%) | 211 | ||||||||
| G/G | 1233 (93%) | 1583 (93%) | 2816 | ||||||||
| 33 | 2Q36_3_MG_433 | rs2972147 | 2 | 98.5% | C/C | 542 (41%) | 692 (41%) | 1234 | 1.011 (0.909, 1.125) |
0.84186 | 0.96726 |
| C/T | 596 (45%) | 775 (46%) | 1371 | ||||||||
| T/T | 181 (14%) | 233 (14%) | 414 | ||||||||
| 34 | 10Q11_21_MG_440 | rs559580 | 10 | 99.3% | C/C | 35 (3%) | 44 (3%) | 79 | 1.014 (0.881, 1.167) |
0.84761 | 0.96726 |
| C/T | 357 (27%) | 464 (27%) | 821 | ||||||||
| T/T | 938 (71%) | 1204 (70%) | 2142 | ||||||||
| 35 | 2Q36_3_MG_447 | rs7597168 | 2 | 99.4% | C/C | 753 (57%) | 971 (57%) | 1724 | 1.010 (0.895, 1.139) |
0.87254 | 0.96726 |
| C/T | 501 (38%) | 642 (37%) | 1143 | ||||||||
| T/T | 76 (6%) | 104 (6%) | 180 | ||||||||
| 36 | 1Q31_2_MG_453 | rs1936982 | 1 | 99.0% | C/C | 168 (13%) | 225 (13%) | 393 | 1.008 (0.906, 1.121) |
0.88225 | 0.96726 |
| C/T | 591 (45%) | 738 (43%) | 1329 | ||||||||
| T/T | 566 (43%) | 745 (44%) | 1311 | ||||||||
| 37 | 10Q11_21_MG_443 | rs687175 | 10 | 99.4% | C/C | 35 (3%) | 44 (3%) | 79 | 1.009 (0.877, 1.161) |
0.90155 | 0.96726 |
| C/T | 358 (27%) | 470 (27%) | 828 | ||||||||
| T/T | 936 (70%) | 1204 (70%) | 2140 | ||||||||
| 38 | 10Q11_21_MG_428 | rs1746048 | 10 | 99.5% | C/C | 938 (71%) | 1207 (70%) | 2145 | 0.992 (0.862, 1.141) |
0.90730 | 0.96726 |
| C/T | 358 (27%) | 468 (27%) | 826 | ||||||||
| T/T | 34 (3%) | 44 (3%) | 78 | ||||||||
| 39 | SEZ6L_MG_427 | rs137209 | 22 | 99.5% | A/A | 142 (11%) | 177 (10%) | 319 | 1.006 (0.900, 1.125) |
0.91150 | 0.96726 |
| A/G | 616 (46%) | 795 (46%) | 1411 | ||||||||
| G/G | 571 (43%) | 748 (43%) | 1319 | ||||||||
| 40 | MTHFD1L_MG_449 | rs12214306 | 6 | 99.1% | C/C | 0 (0%) | 1 (0%) | 1 | 1.013 (0.733, 1.398) |
0.93958 | 0.96726 |
| C/T | 72 (5%) | 88 (5%) | 160 | ||||||||
| T/T | 1254 (95%) | 1621 (95%) | 2875 | ||||||||
| 41 | 10Q11_21_MG_456 | rs513391 | 10 | 99.1% | A/A | 935 (70%) | 1196 (70%) | 2131 | 0.995 (0.865, 1.145) |
0.94680 | 0.96726 |
| A/C | 358 (27%) | 468 (27%) | 826 | ||||||||
| C/C | 35 (3%) | 44 (3%) | 79 | ||||||||
| 42 | 10Q11_21_MG_458 | rs622472 | 10 | 98.3% | A/A | 924 (70%) | 1181 (70%) | 2105 | 1.003 (0.872, 1.154) |
0.96726 | 0.96726 |
| A/C | 357 (27%) | 469 (28%) | 826 | ||||||||
| C/C | 36 (3%) | 45 (3%) | 81 |
Updated on 2008-12-08
