response: (chd1 %in% c('1','2'))
covariates: nonhdl hdla bmi bpm dsmoker hisdiab1
SNP: SMAD3_MG_452
Call:
coxph(formula = y[notmissing] ~ allele[notmissing] + wz[notmissing,
selectedcovariates] + wruaco[notmissing] + strata(wsex[notmissing]) +
cluster(wdata$id[notmissing]), weights = weight[notmissing],
robust = TRUE)
n=3025 (51 observations deleted due to missingness)
coef exp(coef) se(coef) robust se
allele[notmissing] -0.0279 0.972 0.05425 0.07178
wz[notmissing, selectedcovariates]1 0.1977 1.219 0.02536 0.04463
wz[notmissing, selectedcovariates]2 -0.8908 0.410 0.11422 0.14989
wz[notmissing, selectedcovariates]3 0.0118 1.012 0.00793 0.01020
wz[notmissing, selectedcovariates]4 0.0145 1.015 0.00230 0.00306
wz[notmissing, selectedcovariates]5 0.5394 1.715 0.07727 0.10961
wz[notmissing, selectedcovariates]6 0.7824 2.187 0.10169 0.15579
wruaco[notmissing]FIN-EAS_03 0.7677 2.155 0.13065 0.17294
wruaco[notmissing]FIN-EAS_24 0.3257 1.385 0.11930 0.15681
wruaco[notmissing]FIN-WES_03 0.2767 1.319 0.14313 0.18421
wruaco[notmissing]FIN-WES_24 0.1843 1.202 0.13042 0.18926
wruaco[notmissing]FRA-LIL_21 -0.0142 0.986 0.22456 0.34330
wruaco[notmissing]FRA-STR_21 0.0396 1.040 0.19864 0.27401
wruaco[notmissing]FRA-TOU_21 0.5221 1.686 0.20596 0.27855
wruaco[notmissing]SWE-NSW_02 0.4209 1.523 0.21305 0.28990
wruaco[notmissing]SWE-NSW_03 -0.0873 0.916 0.29727 0.36231
wruaco[notmissing]UNK-BEL_21 0.6226 1.864 0.14660 0.19977
z p
allele[notmissing] -0.3891 7.0e-01
wz[notmissing, selectedcovariates]1 4.4290 9.5e-06
wz[notmissing, selectedcovariates]2 -5.9431 2.8e-09
wz[notmissing, selectedcovariates]3 1.1558 2.5e-01
wz[notmissing, selectedcovariates]4 4.7215 2.3e-06
wz[notmissing, selectedcovariates]5 4.9208 8.6e-07
wz[notmissing, selectedcovariates]6 5.0220 5.1e-07
wruaco[notmissing]FIN-EAS_03 4.4391 9.0e-06
wruaco[notmissing]FIN-EAS_24 2.0771 3.8e-02
wruaco[notmissing]FIN-WES_03 1.5021 1.3e-01
wruaco[notmissing]FIN-WES_24 0.9739 3.3e-01
wruaco[notmissing]FRA-LIL_21 -0.0413 9.7e-01
wruaco[notmissing]FRA-STR_21 0.1445 8.9e-01
wruaco[notmissing]FRA-TOU_21 1.8744 6.1e-02
wruaco[notmissing]SWE-NSW_02 1.4519 1.5e-01
wruaco[notmissing]SWE-NSW_03 -0.2408 8.1e-01
wruaco[notmissing]UNK-BEL_21 3.1166 1.8e-03
exp(coef) exp(-coef) lower .95 upper .95
allele[notmissing] 0.972 1.028 0.845 1.12
wz[notmissing, selectedcovariates]1 1.219 0.821 1.116 1.33
wz[notmissing, selectedcovariates]2 0.410 2.437 0.306 0.55
wz[notmissing, selectedcovariates]3 1.012 0.988 0.992 1.03
wz[notmissing, selectedcovariates]4 1.015 0.986 1.008 1.02
wz[notmissing, selectedcovariates]5 1.715 0.583 1.383 2.13
wz[notmissing, selectedcovariates]6 2.187 0.457 1.611 2.97
wruaco[notmissing]FIN-EAS_03 2.155 0.464 1.535 3.02
wruaco[notmissing]FIN-EAS_24 1.385 0.722 1.019 1.88
wruaco[notmissing]FIN-WES_03 1.319 0.758 0.919 1.89
wruaco[notmissing]FIN-WES_24 1.202 0.832 0.830 1.74
wruaco[notmissing]FRA-LIL_21 0.986 1.014 0.503 1.93
wruaco[notmissing]FRA-STR_21 1.040 0.961 0.608 1.78
wruaco[notmissing]FRA-TOU_21 1.686 0.593 0.976 2.91
wruaco[notmissing]SWE-NSW_02 1.523 0.656 0.863 2.69
wruaco[notmissing]SWE-NSW_03 0.916 1.091 0.451 1.86
wruaco[notmissing]UNK-BEL_21 1.864 0.537 1.260 2.76
Rsquare= 0.112 (max possible= 0.995 )
Likelihood ratio test= 361 on 17 df, p=0
Wald test = 171 on 17 df, p=0
Score (logrank) test = 389 on 17 df, p=0, Robust = 189 p=0
(Note: the likelihood ratio and score tests assume independence of
observations within a cluster, the Wald and robust score tests do not).
Updated on 2008-06-04