response: (death=='1')
covariates: nonhdl hdla bmi bpm dsmoker hisdiab1
SNP: MTHFD1L_MG_449
Call:
coxph(formula = y[notmissing] ~ allele[notmissing] + wz[notmissing,
selectedcovariates] + wruaco[notmissing] + strata(wsex[notmissing]) +
cluster(wdata$id[notmissing]), weights = weight[notmissing],
robust = TRUE)
n=3442 (65 observations deleted due to missingness)
coef exp(coef) se(coef) robust se
allele[notmissing] -0.19017 0.8268 0.12920 0.16744
wz[notmissing, selectedcovariates]1 -0.04643 0.9546 0.02552 0.03369
wz[notmissing, selectedcovariates]2 -0.21935 0.8030 0.08988 0.12156
wz[notmissing, selectedcovariates]3 -0.01497 0.9851 0.00711 0.00967
wz[notmissing, selectedcovariates]4 0.00958 1.0096 0.00202 0.00273
wz[notmissing, selectedcovariates]5 0.59827 1.8190 0.06852 0.09434
wz[notmissing, selectedcovariates]6 0.53981 1.7157 0.09694 0.14271
wruaco[notmissing]FIN-EAS_03 0.01441 1.0145 0.12680 0.16645
wruaco[notmissing]FIN-EAS_24 -0.33196 0.7175 0.10738 0.14253
wruaco[notmissing]FIN-WES_03 -0.00417 0.9958 0.12115 0.15687
wruaco[notmissing]FIN-WES_24 -0.28932 0.7488 0.11191 0.15573
wruaco[notmissing]FRA-LIL_21 -2.82606 0.0592 0.71179 0.74617
wruaco[notmissing]FRA-STR_21 -0.28460 0.7523 0.19749 0.26015
wruaco[notmissing]FRA-TOU_21 -0.52765 0.5900 0.24855 0.29754
wruaco[notmissing]SWE-NSW_02 -0.24079 0.7860 0.17212 0.22788
wruaco[notmissing]SWE-NSW_03 -0.65008 0.5220 0.18413 0.22853
wruaco[notmissing]UNK-BEL_21 -0.31708 0.7283 0.17668 0.21893
z p
allele[notmissing] -1.1358 2.6e-01
wz[notmissing, selectedcovariates]1 -1.3782 1.7e-01
wz[notmissing, selectedcovariates]2 -1.8045 7.1e-02
wz[notmissing, selectedcovariates]3 -1.5473 1.2e-01
wz[notmissing, selectedcovariates]4 3.5135 4.4e-04
wz[notmissing, selectedcovariates]5 6.3413 2.3e-10
wz[notmissing, selectedcovariates]6 3.7826 1.6e-04
wruaco[notmissing]FIN-EAS_03 0.0866 9.3e-01
wruaco[notmissing]FIN-EAS_24 -2.3290 2.0e-02
wruaco[notmissing]FIN-WES_03 -0.0266 9.8e-01
wruaco[notmissing]FIN-WES_24 -1.8579 6.3e-02
wruaco[notmissing]FRA-LIL_21 -3.7874 1.5e-04
wruaco[notmissing]FRA-STR_21 -1.0940 2.7e-01
wruaco[notmissing]FRA-TOU_21 -1.7734 7.6e-02
wruaco[notmissing]SWE-NSW_02 -1.0566 2.9e-01
wruaco[notmissing]SWE-NSW_03 -2.8446 4.4e-03
wruaco[notmissing]UNK-BEL_21 -1.4483 1.5e-01
exp(coef) exp(-coef) lower .95 upper .95
allele[notmissing] 0.8268 1.209 0.5955 1.148
wz[notmissing, selectedcovariates]1 0.9546 1.048 0.8936 1.020
wz[notmissing, selectedcovariates]2 0.8030 1.245 0.6328 1.019
wz[notmissing, selectedcovariates]3 0.9851 1.015 0.9666 1.004
wz[notmissing, selectedcovariates]4 1.0096 0.990 1.0042 1.015
wz[notmissing, selectedcovariates]5 1.8190 0.550 1.5119 2.188
wz[notmissing, selectedcovariates]6 1.7157 0.583 1.2971 2.269
wruaco[notmissing]FIN-EAS_03 1.0145 0.986 0.7321 1.406
wruaco[notmissing]FIN-EAS_24 0.7175 1.394 0.5426 0.949
wruaco[notmissing]FIN-WES_03 0.9958 1.004 0.7322 1.354
wruaco[notmissing]FIN-WES_24 0.7488 1.336 0.5518 1.016
wruaco[notmissing]FRA-LIL_21 0.0592 16.879 0.0137 0.256
wruaco[notmissing]FRA-STR_21 0.7523 1.329 0.4518 1.253
wruaco[notmissing]FRA-TOU_21 0.5900 1.695 0.3293 1.057
wruaco[notmissing]SWE-NSW_02 0.7860 1.272 0.5029 1.229
wruaco[notmissing]SWE-NSW_03 0.5220 1.916 0.3335 0.817
wruaco[notmissing]UNK-BEL_21 0.7283 1.373 0.4742 1.119
Rsquare= 0.077 (max possible= 0.998 )
Likelihood ratio test= 276 on 17 df, p=0
Wald test = 142 on 17 df, p=0
Score (logrank) test = 257 on 17 df, p=0, Robust = 150 p=0
(Note: the likelihood ratio and score tests assume independence of
observations within a cluster, the Wald and robust score tests do not).
Updated on 2008-06-04