Cox regression for DEATH endpoint, test for multiplicative allele effects, men and women model for CELSR2_MG

response: (death=='1') 
covariates: dsmoker 
SNP: CELSR2_MG_438 
Call:
coxph(formula = y[notmissing] ~ allele[notmissing] + wz[notmissing, 
    selectedcovariates] + wruaco[notmissing] + strata(wsex[notmissing]) + 
    cluster(wdata$id[notmissing]), weights = weight[notmissing], 
    robust = TRUE)

  n= 3511 
                                      coef exp(coef) se(coef) robust se      z
allele[notmissing]                  0.0437    1.0447   0.0468    0.0626  0.698
wz[notmissing, selectedcovariates]  0.5632    1.7563   0.0667    0.0911  6.183
wruaco[notmissing]FIN-EAS_03        0.0403    1.0411   0.1246    0.1621  0.248
wruaco[notmissing]FIN-EAS_24       -0.1850    0.8311   0.1015    0.1353 -1.367
wruaco[notmissing]FIN-WES_03        0.0283    1.0287   0.1196    0.1548  0.183
wruaco[notmissing]FIN-WES_24       -0.2415    0.7854   0.1065    0.1474 -1.638
wruaco[notmissing]FRA-LIL_21       -2.5304    0.0796   0.5831    0.6156 -4.111
wruaco[notmissing]FRA-STR_21       -0.3054    0.7368   0.1942    0.2483 -1.230
wruaco[notmissing]FRA-TOU_21       -0.5628    0.5696   0.2320    0.2775 -2.028
wruaco[notmissing]SWE-NSW_02       -0.2325    0.7926   0.1674    0.2179 -1.067
wruaco[notmissing]SWE-NSW_03       -0.6142    0.5411   0.1805    0.2179 -2.819
wruaco[notmissing]UNK-BEL_21       -0.2893    0.7488   0.1736    0.2117 -1.367
                                         p
allele[notmissing]                 4.9e-01
wz[notmissing, selectedcovariates] 6.3e-10
wruaco[notmissing]FIN-EAS_03       8.0e-01
wruaco[notmissing]FIN-EAS_24       1.7e-01
wruaco[notmissing]FIN-WES_03       8.5e-01
wruaco[notmissing]FIN-WES_24       1.0e-01
wruaco[notmissing]FRA-LIL_21       3.9e-05
wruaco[notmissing]FRA-STR_21       2.2e-01
wruaco[notmissing]FRA-TOU_21       4.3e-02
wruaco[notmissing]SWE-NSW_02       2.9e-01
wruaco[notmissing]SWE-NSW_03       4.8e-03
wruaco[notmissing]UNK-BEL_21       1.7e-01

                                   exp(coef) exp(-coef) lower .95 upper .95
allele[notmissing]                    1.0447      0.957    0.9241     1.181
wz[notmissing, selectedcovariates]    1.7563      0.569    1.4692     2.100
wruaco[notmissing]FIN-EAS_03          1.0411      0.961    0.7578     1.430
wruaco[notmissing]FIN-EAS_24          0.8311      1.203    0.6375     1.084
wruaco[notmissing]FIN-WES_03          1.0287      0.972    0.7595     1.393
wruaco[notmissing]FIN-WES_24          0.7854      1.273    0.5884     1.049
wruaco[notmissing]FRA-LIL_21          0.0796     12.558    0.0238     0.266
wruaco[notmissing]FRA-STR_21          0.7368      1.357    0.4529     1.199
wruaco[notmissing]FRA-TOU_21          0.5696      1.756    0.3306     0.981
wruaco[notmissing]SWE-NSW_02          0.7926      1.262    0.5171     1.215
wruaco[notmissing]SWE-NSW_03          0.5411      1.848    0.3530     0.829
wruaco[notmissing]UNK-BEL_21          0.7488      1.336    0.4945     1.134

Rsquare= 0.058   (max possible= 0.998 )
Likelihood ratio test= 210  on 12 df,   p=0
Wald test            = 111  on 12 df,   p=0
Score (logrank) test = 190  on 12 df,   p=0,   Robust = 117  p=0

  (Note: the likelihood ratio and score tests assume independence of
     observations within a cluster, the Wald and robust score tests do not).
Updated on 2008-06-04