response: (stroke4 %in% c('2','4','6'))
covariates: nonhdl hdla bmi bpm dsmoker hisdiab1
SNP: 10Q11_21_MG_458
Call:
coxph(formula = y[notmissing] ~ allele[notmissing] + wz[notmissing,
selectedcovariates] + wruaco[notmissing] + strata(wsex[notmissing]) +
cluster(wdata$id[notmissing]), weights = weight[notmissing],
robust = TRUE)
n=2404 (42 observations deleted due to missingness)
coef exp(coef) se(coef) robust se
allele[notmissing] 0.16889 1.184 0.10266 0.11240
wz[notmissing, selectedcovariates]1 0.06320 1.065 0.04548 0.05290
wz[notmissing, selectedcovariates]2 -0.78399 0.457 0.18210 0.20570
wz[notmissing, selectedcovariates]3 0.00611 1.006 0.01243 0.01338
wz[notmissing, selectedcovariates]4 0.01568 1.016 0.00383 0.00442
wz[notmissing, selectedcovariates]5 0.40098 1.493 0.12945 0.14368
wz[notmissing, selectedcovariates]6 0.77822 2.178 0.16241 0.20131
wruaco[notmissing]FIN-EAS_03 0.36647 1.443 0.21991 0.23769
wruaco[notmissing]FIN-EAS_24 -0.09240 0.912 0.19590 0.22590
wruaco[notmissing]FIN-WES_03 -0.00871 0.991 0.22935 0.24944
wruaco[notmissing]FIN-WES_24 -0.12719 0.881 0.21028 0.24723
wruaco[notmissing]FRA-LIL_21 -0.96584 0.381 0.52147 0.57454
wruaco[notmissing]FRA-STR_21 -1.04979 0.350 0.48026 0.52651
wruaco[notmissing]FRA-TOU_21 -0.63864 0.528 0.53036 0.57395
wruaco[notmissing]SWE-NSW_02 -0.07890 0.924 0.30938 0.37133
wruaco[notmissing]SWE-NSW_03 0.13965 1.150 0.26988 0.30318
wruaco[notmissing]UNK-BEL_21 -0.71274 0.490 0.37709 0.39758
z p
allele[notmissing] 1.5026 0.13000
wz[notmissing, selectedcovariates]1 1.1946 0.23000
wz[notmissing, selectedcovariates]2 -3.8113 0.00014
wz[notmissing, selectedcovariates]3 0.4563 0.65000
wz[notmissing, selectedcovariates]4 3.5435 0.00039
wz[notmissing, selectedcovariates]5 2.7909 0.00530
wz[notmissing, selectedcovariates]6 3.8658 0.00011
wruaco[notmissing]FIN-EAS_03 1.5418 0.12000
wruaco[notmissing]FIN-EAS_24 -0.4090 0.68000
wruaco[notmissing]FIN-WES_03 -0.0349 0.97000
wruaco[notmissing]FIN-WES_24 -0.5145 0.61000
wruaco[notmissing]FRA-LIL_21 -1.6810 0.09300
wruaco[notmissing]FRA-STR_21 -1.9939 0.04600
wruaco[notmissing]FRA-TOU_21 -1.1127 0.27000
wruaco[notmissing]SWE-NSW_02 -0.2125 0.83000
wruaco[notmissing]SWE-NSW_03 0.4606 0.65000
wruaco[notmissing]UNK-BEL_21 -1.7927 0.07300
exp(coef) exp(-coef) lower .95 upper .95
allele[notmissing] 1.184 0.845 0.950 1.476
wz[notmissing, selectedcovariates]1 1.065 0.939 0.960 1.182
wz[notmissing, selectedcovariates]2 0.457 2.190 0.305 0.683
wz[notmissing, selectedcovariates]3 1.006 0.994 0.980 1.033
wz[notmissing, selectedcovariates]4 1.016 0.984 1.007 1.025
wz[notmissing, selectedcovariates]5 1.493 0.670 1.127 1.979
wz[notmissing, selectedcovariates]6 2.178 0.459 1.468 3.231
wruaco[notmissing]FIN-EAS_03 1.443 0.693 0.905 2.299
wruaco[notmissing]FIN-EAS_24 0.912 1.097 0.586 1.420
wruaco[notmissing]FIN-WES_03 0.991 1.009 0.608 1.616
wruaco[notmissing]FIN-WES_24 0.881 1.136 0.542 1.430
wruaco[notmissing]FRA-LIL_21 0.381 2.627 0.123 1.174
wruaco[notmissing]FRA-STR_21 0.350 2.857 0.125 0.982
wruaco[notmissing]FRA-TOU_21 0.528 1.894 0.171 1.626
wruaco[notmissing]SWE-NSW_02 0.924 1.082 0.446 1.913
wruaco[notmissing]SWE-NSW_03 1.150 0.870 0.635 2.083
wruaco[notmissing]UNK-BEL_21 0.490 2.040 0.225 1.069
Rsquare= 0.045 (max possible= 0.914 )
Likelihood ratio test= 109 on 17 df, p=1.55e-15
Wald test = 85.6 on 17 df, p=3.78e-11
Score (logrank) test = 112 on 17 df, p=5.55e-16, Robust = 74.5 p=3.59e-09
(Note: the likelihood ratio and score tests assume independence of
observations within a cluster, the Wald and robust score tests do not).
Updated on 2008-06-04