response: (stroke4 %in% c('2','4','6'))
covariates: nonhdl hdla bmi bpm dsmoker hisdiab1
SNP: 19Q12_MG_446
Call:
coxph(formula = y[notmissing] ~ allele[notmissing] + wz[notmissing,
selectedcovariates] + wruaco[notmissing] + strata(wsex[notmissing]) +
cluster(wdata$id[notmissing]), weights = weight[notmissing],
robust = TRUE)
n=2394 (43 observations deleted due to missingness)
coef exp(coef) se(coef) robust se
allele[notmissing] 0.07117 1.074 0.10045 0.11449
wz[notmissing, selectedcovariates]1 0.06976 1.072 0.04559 0.05338
wz[notmissing, selectedcovariates]2 -0.74678 0.474 0.18307 0.20808
wz[notmissing, selectedcovariates]3 0.00855 1.009 0.01246 0.01351
wz[notmissing, selectedcovariates]4 0.01543 1.016 0.00383 0.00442
wz[notmissing, selectedcovariates]5 0.40386 1.498 0.12943 0.14440
wz[notmissing, selectedcovariates]6 0.81631 2.262 0.16125 0.20084
wruaco[notmissing]FIN-EAS_03 0.35167 1.421 0.22105 0.23966
wruaco[notmissing]FIN-EAS_24 -0.10078 0.904 0.19765 0.22810
wruaco[notmissing]FIN-WES_03 -0.01653 0.984 0.22776 0.25003
wruaco[notmissing]FIN-WES_24 -0.10919 0.897 0.20705 0.24265
wruaco[notmissing]FRA-LIL_21 -0.96815 0.380 0.52122 0.57349
wruaco[notmissing]FRA-STR_21 -1.08894 0.337 0.47976 0.52676
wruaco[notmissing]FRA-TOU_21 -0.67736 0.508 0.53136 0.57553
wruaco[notmissing]SWE-NSW_02 0.04881 1.050 0.29310 0.35214
wruaco[notmissing]SWE-NSW_03 0.09380 1.098 0.27022 0.30056
wruaco[notmissing]UNK-BEL_21 -0.80437 0.447 0.39517 0.42073
z p
allele[notmissing] 0.6216 5.3e-01
wz[notmissing, selectedcovariates]1 1.3068 1.9e-01
wz[notmissing, selectedcovariates]2 -3.5888 3.3e-04
wz[notmissing, selectedcovariates]3 0.6326 5.3e-01
wz[notmissing, selectedcovariates]4 3.4887 4.9e-04
wz[notmissing, selectedcovariates]5 2.7968 5.2e-03
wz[notmissing, selectedcovariates]6 4.0646 4.8e-05
wruaco[notmissing]FIN-EAS_03 1.4674 1.4e-01
wruaco[notmissing]FIN-EAS_24 -0.4418 6.6e-01
wruaco[notmissing]FIN-WES_03 -0.0661 9.5e-01
wruaco[notmissing]FIN-WES_24 -0.4500 6.5e-01
wruaco[notmissing]FRA-LIL_21 -1.6882 9.1e-02
wruaco[notmissing]FRA-STR_21 -2.0672 3.9e-02
wruaco[notmissing]FRA-TOU_21 -1.1769 2.4e-01
wruaco[notmissing]SWE-NSW_02 0.1386 8.9e-01
wruaco[notmissing]SWE-NSW_03 0.3121 7.5e-01
wruaco[notmissing]UNK-BEL_21 -1.9119 5.6e-02
exp(coef) exp(-coef) lower .95 upper .95
allele[notmissing] 1.074 0.931 0.858 1.344
wz[notmissing, selectedcovariates]1 1.072 0.933 0.966 1.191
wz[notmissing, selectedcovariates]2 0.474 2.110 0.315 0.713
wz[notmissing, selectedcovariates]3 1.009 0.991 0.982 1.036
wz[notmissing, selectedcovariates]4 1.016 0.985 1.007 1.024
wz[notmissing, selectedcovariates]5 1.498 0.668 1.128 1.988
wz[notmissing, selectedcovariates]6 2.262 0.442 1.526 3.353
wruaco[notmissing]FIN-EAS_03 1.421 0.704 0.889 2.274
wruaco[notmissing]FIN-EAS_24 0.904 1.106 0.578 1.414
wruaco[notmissing]FIN-WES_03 0.984 1.017 0.603 1.606
wruaco[notmissing]FIN-WES_24 0.897 1.115 0.557 1.443
wruaco[notmissing]FRA-LIL_21 0.380 2.633 0.123 1.169
wruaco[notmissing]FRA-STR_21 0.337 2.971 0.120 0.945
wruaco[notmissing]FRA-TOU_21 0.508 1.969 0.164 1.569
wruaco[notmissing]SWE-NSW_02 1.050 0.952 0.527 2.094
wruaco[notmissing]SWE-NSW_03 1.098 0.910 0.609 1.980
wruaco[notmissing]UNK-BEL_21 0.447 2.235 0.196 1.020
Rsquare= 0.045 (max possible= 0.915 )
Likelihood ratio test= 110 on 17 df, p=1.11e-15
Wald test = 86.3 on 17 df, p=2.87e-11
Score (logrank) test = 114 on 17 df, p=2.22e-16, Robust = 73.8 p=4.74e-09
(Note: the likelihood ratio and score tests assume independence of
observations within a cluster, the Wald and robust score tests do not).
Updated on 2008-06-04