response: (stroke1 %in% c('1','2'))
covariates: nonhdl hdla bmi bpm dsmoker hisdiab1
SNP: 19Q12_MG_446
Call:
coxph(formula = y[notmissing] ~ allele[notmissing] + wz[notmissing,
selectedcovariates] + wruaco[notmissing] + strata(wsex[notmissing]) +
cluster(wdata$id[notmissing]), weights = weight[notmissing],
robust = TRUE)
n=2527 (44 observations deleted due to missingness)
coef exp(coef) se(coef) robust se z
allele[notmissing] 0.0321 1.033 0.08733 0.10252 0.313
wz[notmissing, selectedcovariates]1 0.0453 1.046 0.04023 0.04862 0.931
wz[notmissing, selectedcovariates]2 -0.7769 0.460 0.15748 0.18657 -4.164
wz[notmissing, selectedcovariates]3 -0.0179 0.982 0.01135 0.01317 -1.360
wz[notmissing, selectedcovariates]4 0.0194 1.020 0.00328 0.00391 4.969
wz[notmissing, selectedcovariates]5 0.3837 1.468 0.11075 0.13016 2.948
wz[notmissing, selectedcovariates]6 0.7403 2.096 0.14489 0.19179 3.860
wruaco[notmissing]FIN-EAS_03 0.2575 1.294 0.19287 0.22099 1.165
wruaco[notmissing]FIN-EAS_24 -0.1915 0.826 0.17390 0.20562 -0.931
wruaco[notmissing]FIN-WES_03 0.0963 1.101 0.18806 0.21479 0.448
wruaco[notmissing]FIN-WES_24 -0.1655 0.847 0.17978 0.21907 -0.755
wruaco[notmissing]FRA-LIL_21 -1.2896 0.275 0.51664 0.57052 -2.260
wruaco[notmissing]FRA-STR_21 -0.9089 0.403 0.38441 0.42623 -2.132
wruaco[notmissing]FRA-TOU_21 -1.0167 0.362 0.52355 0.56348 -1.804
wruaco[notmissing]SWE-NSW_02 0.0117 1.012 0.24949 0.32460 0.036
wruaco[notmissing]SWE-NSW_03 0.1013 1.107 0.23227 0.26654 0.380
wruaco[notmissing]UNK-BEL_21 -0.7529 0.471 0.32674 0.35069 -2.147
p
allele[notmissing] 7.5e-01
wz[notmissing, selectedcovariates]1 3.5e-01
wz[notmissing, selectedcovariates]2 3.1e-05
wz[notmissing, selectedcovariates]3 1.7e-01
wz[notmissing, selectedcovariates]4 6.7e-07
wz[notmissing, selectedcovariates]5 3.2e-03
wz[notmissing, selectedcovariates]6 1.1e-04
wruaco[notmissing]FIN-EAS_03 2.4e-01
wruaco[notmissing]FIN-EAS_24 3.5e-01
wruaco[notmissing]FIN-WES_03 6.5e-01
wruaco[notmissing]FIN-WES_24 4.5e-01
wruaco[notmissing]FRA-LIL_21 2.4e-02
wruaco[notmissing]FRA-STR_21 3.3e-02
wruaco[notmissing]FRA-TOU_21 7.1e-02
wruaco[notmissing]SWE-NSW_02 9.7e-01
wruaco[notmissing]SWE-NSW_03 7.0e-01
wruaco[notmissing]UNK-BEL_21 3.2e-02
exp(coef) exp(-coef) lower .95 upper .95
allele[notmissing] 1.033 0.968 0.845 1.262
wz[notmissing, selectedcovariates]1 1.046 0.956 0.951 1.151
wz[notmissing, selectedcovariates]2 0.460 2.175 0.319 0.663
wz[notmissing, selectedcovariates]3 0.982 1.018 0.957 1.008
wz[notmissing, selectedcovariates]4 1.020 0.981 1.012 1.027
wz[notmissing, selectedcovariates]5 1.468 0.681 1.137 1.894
wz[notmissing, selectedcovariates]6 2.096 0.477 1.440 3.053
wruaco[notmissing]FIN-EAS_03 1.294 0.773 0.839 1.995
wruaco[notmissing]FIN-EAS_24 0.826 1.211 0.552 1.236
wruaco[notmissing]FIN-WES_03 1.101 0.908 0.723 1.677
wruaco[notmissing]FIN-WES_24 0.847 1.180 0.552 1.302
wruaco[notmissing]FRA-LIL_21 0.275 3.631 0.090 0.842
wruaco[notmissing]FRA-STR_21 0.403 2.482 0.175 0.929
wruaco[notmissing]FRA-TOU_21 0.362 2.764 0.120 1.092
wruaco[notmissing]SWE-NSW_02 1.012 0.988 0.536 1.912
wruaco[notmissing]SWE-NSW_03 1.107 0.904 0.656 1.866
wruaco[notmissing]UNK-BEL_21 0.471 2.123 0.237 0.937
Rsquare= 0.054 (max possible= 0.956 )
Likelihood ratio test= 140 on 17 df, p=0
Wald test = 97.1 on 17 df, p=3.01e-13
Score (logrank) test = 139 on 17 df, p=0, Robust = 90 p=6.11e-12
(Note: the likelihood ratio and score tests assume independence of
observations within a cluster, the Wald and robust score tests do not).
Updated on 2008-06-04