response: (stroke1 %in% c('1','2'))
covariates: nonhdl hdla bmi bpm dsmoker hisdiab1
SNP: CELSR2_MG_438
Call:
coxph(formula = y[notmissing] ~ allele[notmissing] + wz[notmissing,
selectedcovariates] + wruaco[notmissing] + strata(wsex[notmissing]) +
cluster(wdata$id[notmissing]), weights = weight[notmissing],
robust = TRUE)
n=2562 (45 observations deleted due to missingness)
coef exp(coef) se(coef) robust se
allele[notmissing] 0.04152 1.042 0.07975 0.09488
wz[notmissing, selectedcovariates]1 0.03394 1.035 0.04027 0.04858
wz[notmissing, selectedcovariates]2 -0.77615 0.460 0.15610 0.18383
wz[notmissing, selectedcovariates]3 -0.01849 0.982 0.01131 0.01312
wz[notmissing, selectedcovariates]4 0.01976 1.020 0.00325 0.00390
wz[notmissing, selectedcovariates]5 0.36900 1.446 0.11022 0.12931
wz[notmissing, selectedcovariates]6 0.72284 2.060 0.14461 0.19038
wruaco[notmissing]FIN-EAS_03 0.24144 1.273 0.19257 0.22087
wruaco[notmissing]FIN-EAS_24 -0.19871 0.820 0.17254 0.20432
wruaco[notmissing]FIN-WES_03 0.06482 1.067 0.18861 0.21374
wruaco[notmissing]FIN-WES_24 -0.15557 0.856 0.17816 0.21664
wruaco[notmissing]FRA-LIL_21 -1.29147 0.275 0.51661 0.56881
wruaco[notmissing]FRA-STR_21 -0.94748 0.388 0.38401 0.42216
wruaco[notmissing]FRA-TOU_21 -1.05204 0.349 0.52369 0.56303
wruaco[notmissing]SWE-NSW_02 0.00119 1.001 0.24938 0.32490
wruaco[notmissing]SWE-NSW_03 0.09575 1.100 0.23188 0.26697
wruaco[notmissing]UNK-BEL_21 -0.69198 0.501 0.31645 0.33838
z p
allele[notmissing] 0.43760 6.6e-01
wz[notmissing, selectedcovariates]1 0.69874 4.8e-01
wz[notmissing, selectedcovariates]2 -4.22220 2.4e-05
wz[notmissing, selectedcovariates]3 -1.40864 1.6e-01
wz[notmissing, selectedcovariates]4 5.07241 3.9e-07
wz[notmissing, selectedcovariates]5 2.85348 4.3e-03
wz[notmissing, selectedcovariates]6 3.79679 1.5e-04
wruaco[notmissing]FIN-EAS_03 1.09315 2.7e-01
wruaco[notmissing]FIN-EAS_24 -0.97253 3.3e-01
wruaco[notmissing]FIN-WES_03 0.30327 7.6e-01
wruaco[notmissing]FIN-WES_24 -0.71809 4.7e-01
wruaco[notmissing]FRA-LIL_21 -2.27046 2.3e-02
wruaco[notmissing]FRA-STR_21 -2.24435 2.5e-02
wruaco[notmissing]FRA-TOU_21 -1.86855 6.2e-02
wruaco[notmissing]SWE-NSW_02 0.00365 1.0e+00
wruaco[notmissing]SWE-NSW_03 0.35865 7.2e-01
wruaco[notmissing]UNK-BEL_21 -2.04500 4.1e-02
exp(coef) exp(-coef) lower .95 upper .95
allele[notmissing] 1.042 0.959 0.8655 1.255
wz[notmissing, selectedcovariates]1 1.035 0.967 0.9406 1.138
wz[notmissing, selectedcovariates]2 0.460 2.173 0.3210 0.660
wz[notmissing, selectedcovariates]3 0.982 1.019 0.9568 1.007
wz[notmissing, selectedcovariates]4 1.020 0.980 1.0122 1.028
wz[notmissing, selectedcovariates]5 1.446 0.691 1.1225 1.863
wz[notmissing, selectedcovariates]6 2.060 0.485 1.4186 2.992
wruaco[notmissing]FIN-EAS_03 1.273 0.785 0.8258 1.963
wruaco[notmissing]FIN-EAS_24 0.820 1.220 0.5493 1.224
wruaco[notmissing]FIN-WES_03 1.067 0.937 0.7018 1.622
wruaco[notmissing]FIN-WES_24 0.856 1.168 0.5598 1.309
wruaco[notmissing]FRA-LIL_21 0.275 3.638 0.0901 0.838
wruaco[notmissing]FRA-STR_21 0.388 2.579 0.1695 0.887
wruaco[notmissing]FRA-TOU_21 0.349 2.863 0.1158 1.053
wruaco[notmissing]SWE-NSW_02 1.001 0.999 0.5296 1.893
wruaco[notmissing]SWE-NSW_03 1.100 0.909 0.6521 1.857
wruaco[notmissing]UNK-BEL_21 0.501 1.998 0.2579 0.972
Rsquare= 0.052 (max possible= 0.956 )
Likelihood ratio test= 138 on 17 df, p=0
Wald test = 96.4 on 17 df, p=4.17e-13
Score (logrank) test = 137 on 17 df, p=0, Robust = 90.2 p=5.72e-12
(Note: the likelihood ratio and score tests assume independence of
observations within a cluster, the Wald and robust score tests do not).
Updated on 2008-06-04