response: (stroke1 %in% c('1','2'))
covariates: nonhdl hdla bmi bpm dsmoker hisdiab1
SNP: MIA3_MG_454
Call:
coxph(formula = y[notmissing] ~ allele[notmissing] + wz[notmissing,
selectedcovariates] + wruaco[notmissing] + strata(wsex[notmissing]) +
cluster(wdata$id[notmissing]), weights = weight[notmissing],
robust = TRUE)
n=2538 (43 observations deleted due to missingness)
coef exp(coef) se(coef) robust se
allele[notmissing] -0.09966 0.905 0.08966 0.10275
wz[notmissing, selectedcovariates]1 0.03202 1.033 0.04050 0.04827
wz[notmissing, selectedcovariates]2 -0.78304 0.457 0.15801 0.18687
wz[notmissing, selectedcovariates]3 -0.01667 0.983 0.01131 0.01310
wz[notmissing, selectedcovariates]4 0.02046 1.021 0.00328 0.00392
wz[notmissing, selectedcovariates]5 0.39855 1.490 0.11123 0.13019
wz[notmissing, selectedcovariates]6 0.72185 2.058 0.14712 0.18943
wruaco[notmissing]FIN-EAS_03 0.25457 1.290 0.19467 0.22120
wruaco[notmissing]FIN-EAS_24 -0.24416 0.783 0.17403 0.20630
wruaco[notmissing]FIN-WES_03 0.08766 1.092 0.19012 0.21397
wruaco[notmissing]FIN-WES_24 -0.20023 0.819 0.18241 0.22105
wruaco[notmissing]FRA-LIL_21 -1.27678 0.279 0.51660 0.57039
wruaco[notmissing]FRA-STR_21 -0.86384 0.422 0.38469 0.42559
wruaco[notmissing]FRA-TOU_21 -1.01155 0.364 0.52372 0.56386
wruaco[notmissing]SWE-NSW_02 0.00742 1.007 0.25069 0.32540
wruaco[notmissing]SWE-NSW_03 0.05729 1.059 0.23598 0.27137
wruaco[notmissing]UNK-BEL_21 -0.69564 0.499 0.31732 0.34125
z p
allele[notmissing] -0.9700 3.3e-01
wz[notmissing, selectedcovariates]1 0.6633 5.1e-01
wz[notmissing, selectedcovariates]2 -4.1903 2.8e-05
wz[notmissing, selectedcovariates]3 -1.2728 2.0e-01
wz[notmissing, selectedcovariates]4 5.2140 1.8e-07
wz[notmissing, selectedcovariates]5 3.0613 2.2e-03
wz[notmissing, selectedcovariates]6 3.8107 1.4e-04
wruaco[notmissing]FIN-EAS_03 1.1509 2.5e-01
wruaco[notmissing]FIN-EAS_24 -1.1835 2.4e-01
wruaco[notmissing]FIN-WES_03 0.4097 6.8e-01
wruaco[notmissing]FIN-WES_24 -0.9058 3.7e-01
wruaco[notmissing]FRA-LIL_21 -2.2384 2.5e-02
wruaco[notmissing]FRA-STR_21 -2.0298 4.2e-02
wruaco[notmissing]FRA-TOU_21 -1.7940 7.3e-02
wruaco[notmissing]SWE-NSW_02 0.0228 9.8e-01
wruaco[notmissing]SWE-NSW_03 0.2111 8.3e-01
wruaco[notmissing]UNK-BEL_21 -2.0385 4.2e-02
exp(coef) exp(-coef) lower .95 upper .95
allele[notmissing] 0.905 1.105 0.7400 1.107
wz[notmissing, selectedcovariates]1 1.033 0.968 0.9393 1.135
wz[notmissing, selectedcovariates]2 0.457 2.188 0.3169 0.659
wz[notmissing, selectedcovariates]3 0.983 1.017 0.9585 1.009
wz[notmissing, selectedcovariates]4 1.021 0.980 1.0129 1.029
wz[notmissing, selectedcovariates]5 1.490 0.671 1.1542 1.923
wz[notmissing, selectedcovariates]6 2.058 0.486 1.4199 2.984
wruaco[notmissing]FIN-EAS_03 1.290 0.775 0.8361 1.990
wruaco[notmissing]FIN-EAS_24 0.783 1.277 0.5228 1.174
wruaco[notmissing]FIN-WES_03 1.092 0.916 0.7177 1.660
wruaco[notmissing]FIN-WES_24 0.819 1.222 0.5307 1.262
wruaco[notmissing]FRA-LIL_21 0.279 3.585 0.0912 0.853
wruaco[notmissing]FRA-STR_21 0.422 2.372 0.1831 0.971
wruaco[notmissing]FRA-TOU_21 0.364 2.750 0.1204 1.098
wruaco[notmissing]SWE-NSW_02 1.007 0.993 0.5324 1.906
wruaco[notmissing]SWE-NSW_03 1.059 0.944 0.6221 1.802
wruaco[notmissing]UNK-BEL_21 0.499 2.005 0.2555 0.974
Rsquare= 0.054 (max possible= 0.955 )
Likelihood ratio test= 141 on 17 df, p=0
Wald test = 97.7 on 17 df, p=2.36e-13
Score (logrank) test = 141 on 17 df, p=0, Robust = 90.8 p=4.41e-12
(Note: the likelihood ratio and score tests assume independence of
observations within a cluster, the Wald and robust score tests do not).
Updated on 2008-06-04