response: (stroke1 %in% c('1','2'))
covariates: nonhdl hdla bmi bpm dsmoker hisdiab1
SNP: SMAD3_MG_452
Call:
coxph(formula = y[notmissing] ~ allele[notmissing] + wz[notmissing,
selectedcovariates] + wruaco[notmissing] + strata(wsex[notmissing]) +
cluster(wdata$id[notmissing]), weights = weight[notmissing],
robust = TRUE)
n=2555 (43 observations deleted due to missingness)
coef exp(coef) se(coef) robust se
allele[notmissing] 0.03909 1.040 0.07494 0.08991
wz[notmissing, selectedcovariates]1 0.02814 1.029 0.04049 0.04851
wz[notmissing, selectedcovariates]2 -0.79268 0.453 0.15669 0.18465
wz[notmissing, selectedcovariates]3 -0.01719 0.983 0.01133 0.01305
wz[notmissing, selectedcovariates]4 0.02036 1.021 0.00327 0.00392
wz[notmissing, selectedcovariates]5 0.38056 1.463 0.11047 0.12876
wz[notmissing, selectedcovariates]6 0.67714 1.968 0.14665 0.19114
wruaco[notmissing]FIN-EAS_03 0.22485 1.252 0.19412 0.22269
wruaco[notmissing]FIN-EAS_24 -0.22940 0.795 0.17342 0.20406
wruaco[notmissing]FIN-WES_03 0.08337 1.087 0.18844 0.21272
wruaco[notmissing]FIN-WES_24 -0.17450 0.840 0.18092 0.22013
wruaco[notmissing]FRA-LIL_21 -1.29718 0.273 0.51735 0.57125
wruaco[notmissing]FRA-STR_21 -0.88879 0.411 0.38416 0.42292
wruaco[notmissing]FRA-TOU_21 -1.01031 0.364 0.52345 0.56254
wruaco[notmissing]SWE-NSW_02 -0.00175 0.998 0.24939 0.32234
wruaco[notmissing]SWE-NSW_03 0.05928 1.061 0.23539 0.26973
wruaco[notmissing]UNK-BEL_21 -0.70563 0.494 0.31729 0.33897
z p
allele[notmissing] 0.43480 6.6e-01
wz[notmissing, selectedcovariates]1 0.58012 5.6e-01
wz[notmissing, selectedcovariates]2 -4.29293 1.8e-05
wz[notmissing, selectedcovariates]3 -1.31732 1.9e-01
wz[notmissing, selectedcovariates]4 5.19901 2.0e-07
wz[notmissing, selectedcovariates]5 2.95556 3.1e-03
wz[notmissing, selectedcovariates]6 3.54270 4.0e-04
wruaco[notmissing]FIN-EAS_03 1.00971 3.1e-01
wruaco[notmissing]FIN-EAS_24 -1.12417 2.6e-01
wruaco[notmissing]FIN-WES_03 0.39193 7.0e-01
wruaco[notmissing]FIN-WES_24 -0.79273 4.3e-01
wruaco[notmissing]FRA-LIL_21 -2.27077 2.3e-02
wruaco[notmissing]FRA-STR_21 -2.10153 3.6e-02
wruaco[notmissing]FRA-TOU_21 -1.79598 7.2e-02
wruaco[notmissing]SWE-NSW_02 -0.00541 1.0e+00
wruaco[notmissing]SWE-NSW_03 0.21977 8.3e-01
wruaco[notmissing]UNK-BEL_21 -2.08172 3.7e-02
exp(coef) exp(-coef) lower .95 upper .95
allele[notmissing] 1.040 0.962 0.8719 1.240
wz[notmissing, selectedcovariates]1 1.029 0.972 0.9353 1.131
wz[notmissing, selectedcovariates]2 0.453 2.209 0.3152 0.650
wz[notmissing, selectedcovariates]3 0.983 1.017 0.9581 1.008
wz[notmissing, selectedcovariates]4 1.021 0.980 1.0128 1.028
wz[notmissing, selectedcovariates]5 1.463 0.683 1.1368 1.883
wz[notmissing, selectedcovariates]6 1.968 0.508 1.3533 2.863
wruaco[notmissing]FIN-EAS_03 1.252 0.799 0.8093 1.937
wruaco[notmissing]FIN-EAS_24 0.795 1.258 0.5329 1.186
wruaco[notmissing]FIN-WES_03 1.087 0.920 0.7164 1.649
wruaco[notmissing]FIN-WES_24 0.840 1.191 0.5456 1.293
wruaco[notmissing]FRA-LIL_21 0.273 3.659 0.0892 0.837
wruaco[notmissing]FRA-STR_21 0.411 2.432 0.1795 0.942
wruaco[notmissing]FRA-TOU_21 0.364 2.746 0.1209 1.097
wruaco[notmissing]SWE-NSW_02 0.998 1.002 0.5307 1.878
wruaco[notmissing]SWE-NSW_03 1.061 0.942 0.6254 1.800
wruaco[notmissing]UNK-BEL_21 0.494 2.025 0.2541 0.960
Rsquare= 0.052 (max possible= 0.955 )
Likelihood ratio test= 138 on 17 df, p=0
Wald test = 95.6 on 17 df, p=5.72e-13
Score (logrank) test = 136 on 17 df, p=0, Robust = 89.5 p=7.58e-12
(Note: the likelihood ratio and score tests assume independence of
observations within a cluster, the Wald and robust score tests do not).
Updated on 2008-06-04