response: (stroke2=='1') 
covariates: dsmoker 
SNP: SMAD3_MG_452 
Call:
coxph(formula = y[notmissing] ~ allele[notmissing] + wz[notmissing, 
    selectedcovariates] + wruaco[notmissing] + strata(wsex[notmissing]) + 
    cluster(wdata$id[notmissing]), weights = weight[notmissing], 
    robust = TRUE)

  n= 2153 
                                        coef exp(coef) se(coef) robust se
allele[notmissing]                   0.00981  1.01e+00    0.184     0.196
wz[notmissing, selectedcovariates]   0.22629  1.25e+00    0.264     0.267
wruaco[notmissing]FIN-EAS_03        -1.44477  2.36e-01    0.785     0.810
wruaco[notmissing]FIN-EAS_24        -0.80971  4.45e-01    0.458     0.459
wruaco[notmissing]FIN-WES_03        -0.40781  6.65e-01    0.514     0.497
wruaco[notmissing]FIN-WES_24        -0.94222  3.90e-01    0.481     0.548
wruaco[notmissing]FRA-LIL_21       -16.58173  6.29e-08 2620.918     0.369
wruaco[notmissing]FRA-STR_21        -0.37443  6.88e-01    0.812     0.775
wruaco[notmissing]FRA-TOU_21       -16.61359  6.09e-08 2534.528     0.395
wruaco[notmissing]SWE-NSW_02         0.05286  1.05e+00    0.560     0.589
wruaco[notmissing]SWE-NSW_03        -0.48602  6.15e-01    0.575     0.563
wruaco[notmissing]UNK-BEL_21        -0.09394  9.10e-01    0.648     0.626
                                          z     p
allele[notmissing]                   0.0500 0.960
wz[notmissing, selectedcovariates]   0.8466 0.400
wruaco[notmissing]FIN-EAS_03        -1.7846 0.074
wruaco[notmissing]FIN-EAS_24        -1.7625 0.078
wruaco[notmissing]FIN-WES_03        -0.8211 0.410
wruaco[notmissing]FIN-WES_24        -1.7197 0.085
wruaco[notmissing]FRA-LIL_21       -44.9084 0.000
wruaco[notmissing]FRA-STR_21        -0.4832 0.630
wruaco[notmissing]FRA-TOU_21       -42.0369 0.000
wruaco[notmissing]SWE-NSW_02         0.0898 0.930
wruaco[notmissing]SWE-NSW_03        -0.8629 0.390
wruaco[notmissing]UNK-BEL_21        -0.1500 0.880

                                   exp(coef) exp(-coef) lower .95 upper .95
allele[notmissing]                  1.01e+00   9.90e-01  6.87e-01  1.48e+00
wz[notmissing, selectedcovariates]  1.25e+00   7.97e-01  7.43e-01  2.12e+00
wruaco[notmissing]FIN-EAS_03        2.36e-01   4.24e+00  4.82e-02  1.15e+00
wruaco[notmissing]FIN-EAS_24        4.45e-01   2.25e+00  1.81e-01  1.09e+00
wruaco[notmissing]FIN-WES_03        6.65e-01   1.50e+00  2.51e-01  1.76e+00
wruaco[notmissing]FIN-WES_24        3.90e-01   2.57e+00  1.33e-01  1.14e+00
wruaco[notmissing]FRA-LIL_21        6.29e-08   1.59e+07  3.05e-08  1.30e-07
wruaco[notmissing]FRA-STR_21        6.88e-01   1.45e+00  1.51e-01  3.14e+00
wruaco[notmissing]FRA-TOU_21        6.09e-08   1.64e+07  2.81e-08  1.32e-07
wruaco[notmissing]SWE-NSW_02        1.05e+00   9.49e-01  3.33e-01  3.34e+00
wruaco[notmissing]SWE-NSW_03        6.15e-01   1.63e+00  2.04e-01  1.85e+00
wruaco[notmissing]UNK-BEL_21        9.10e-01   1.10e+00  2.67e-01  3.11e+00

Rsquare= 0.01   (max possible= 0.459 )
Likelihood ratio test= 21.9  on 12 df,   p=0.0383
Wald test            = 3937  on 12 df,   p=0
Score (logrank) test = 17.7  on 12 df,   p=0.126,   Robust = 28.9  p=0.00405

  (Note: the likelihood ratio and score tests assume independence of
     observations within a cluster, the Wald and robust score tests do not).

Updated on 2008-06-04