response: (stroke3 %in% c('1','2'))
covariates: nonhdl hdla bmi bpm dsmoker hisdiab1
SNP: 19Q12_MG_446
Call:
coxph(formula = y[notmissing] ~ allele[notmissing] + wz[notmissing,
selectedcovariates] + wruaco[notmissing] + strata(wsex[notmissing]) +
cluster(wdata$id[notmissing]), weights = weight[notmissing],
robust = TRUE)
n=2414 (44 observations deleted due to missingness)
coef exp(coef) se(coef) robust se
allele[notmissing] 0.05354 1.055 0.09847 0.11158
wz[notmissing, selectedcovariates]1 0.07077 1.073 0.04461 0.05308
wz[notmissing, selectedcovariates]2 -0.74663 0.474 0.17835 0.20354
wz[notmissing, selectedcovariates]3 -0.00138 0.999 0.01247 0.01391
wz[notmissing, selectedcovariates]4 0.01605 1.016 0.00372 0.00429
wz[notmissing, selectedcovariates]5 0.37473 1.455 0.12604 0.14000
wz[notmissing, selectedcovariates]6 0.79031 2.204 0.16039 0.20013
wruaco[notmissing]FIN-EAS_03 0.25886 1.295 0.21859 0.23797
wruaco[notmissing]FIN-EAS_24 -0.17095 0.843 0.19369 0.22334
wruaco[notmissing]FIN-WES_03 -0.18348 0.832 0.23040 0.24879
wruaco[notmissing]FIN-WES_24 -0.19724 0.821 0.20292 0.23839
wruaco[notmissing]FRA-LIL_21 -1.02958 0.357 0.52070 0.57098
wruaco[notmissing]FRA-STR_21 -1.15357 0.316 0.47851 0.52274
wruaco[notmissing]FRA-TOU_21 -0.77283 0.462 0.53011 0.57274
wruaco[notmissing]SWE-NSW_02 0.03067 1.031 0.28452 0.33981
wruaco[notmissing]SWE-NSW_03 0.04581 1.047 0.26284 0.29263
wruaco[notmissing]UNK-BEL_21 -0.78448 0.456 0.37579 0.40206
z p
allele[notmissing] 0.4799 6.3e-01
wz[notmissing, selectedcovariates]1 1.3332 1.8e-01
wz[notmissing, selectedcovariates]2 -3.6682 2.4e-04
wz[notmissing, selectedcovariates]3 -0.0993 9.2e-01
wz[notmissing, selectedcovariates]4 3.7364 1.9e-04
wz[notmissing, selectedcovariates]5 2.6766 7.4e-03
wz[notmissing, selectedcovariates]6 3.9490 7.8e-05
wruaco[notmissing]FIN-EAS_03 1.0878 2.8e-01
wruaco[notmissing]FIN-EAS_24 -0.7654 4.4e-01
wruaco[notmissing]FIN-WES_03 -0.7375 4.6e-01
wruaco[notmissing]FIN-WES_24 -0.8274 4.1e-01
wruaco[notmissing]FRA-LIL_21 -1.8032 7.1e-02
wruaco[notmissing]FRA-STR_21 -2.2068 2.7e-02
wruaco[notmissing]FRA-TOU_21 -1.3494 1.8e-01
wruaco[notmissing]SWE-NSW_02 0.0903 9.3e-01
wruaco[notmissing]SWE-NSW_03 0.1566 8.8e-01
wruaco[notmissing]UNK-BEL_21 -1.9512 5.1e-02
exp(coef) exp(-coef) lower .95 upper .95
allele[notmissing] 1.055 0.948 0.848 1.313
wz[notmissing, selectedcovariates]1 1.073 0.932 0.967 1.191
wz[notmissing, selectedcovariates]2 0.474 2.110 0.318 0.706
wz[notmissing, selectedcovariates]3 0.999 1.001 0.972 1.026
wz[notmissing, selectedcovariates]4 1.016 0.984 1.008 1.025
wz[notmissing, selectedcovariates]5 1.455 0.687 1.106 1.914
wz[notmissing, selectedcovariates]6 2.204 0.454 1.489 3.263
wruaco[notmissing]FIN-EAS_03 1.295 0.772 0.813 2.065
wruaco[notmissing]FIN-EAS_24 0.843 1.186 0.544 1.306
wruaco[notmissing]FIN-WES_03 0.832 1.201 0.511 1.355
wruaco[notmissing]FIN-WES_24 0.821 1.218 0.515 1.310
wruaco[notmissing]FRA-LIL_21 0.357 2.800 0.117 1.094
wruaco[notmissing]FRA-STR_21 0.316 3.170 0.113 0.879
wruaco[notmissing]FRA-TOU_21 0.462 2.166 0.150 1.419
wruaco[notmissing]SWE-NSW_02 1.031 0.970 0.530 2.007
wruaco[notmissing]SWE-NSW_03 1.047 0.955 0.590 1.858
wruaco[notmissing]UNK-BEL_21 0.456 2.191 0.208 1.004
Rsquare= 0.044 (max possible= 0.923 )
Likelihood ratio test= 109 on 17 df, p=2e-15
Wald test = 83.5 on 17 df, p=8.95e-11
Score (logrank) test = 111 on 17 df, p=7.77e-16, Robust = 73.4 p=5.64e-09
(Note: the likelihood ratio and score tests assume independence of
observations within a cluster, the Wald and robust score tests do not).
Updated on 2008-06-04