response: (stroke3 %in% c('1','2')) 
covariates: dsmoker 
SNP: MTHFD1L_MG_449 
Call:
coxph(formula = y[notmissing] ~ allele[notmissing] + wz[notmissing, 
    selectedcovariates] + wruaco[notmissing] + strata(wsex[notmissing]) + 
    cluster(wdata$id[notmissing]), weights = weight[notmissing], 
    robust = TRUE)

  n= 2486 
                                      coef exp(coef) se(coef) robust se      z
allele[notmissing]                 -0.2029     0.816    0.241     0.275 -0.738
wz[notmissing, selectedcovariates]  0.3138     1.369    0.122     0.133  2.365
wruaco[notmissing]FIN-EAS_03        0.2175     1.243    0.214     0.228  0.952
wruaco[notmissing]FIN-EAS_24       -0.1307     0.877    0.183     0.207 -0.633
wruaco[notmissing]FIN-WES_03       -0.2043     0.815    0.232     0.246 -0.830
wruaco[notmissing]FIN-WES_24       -0.2213     0.801    0.197     0.227 -0.977
wruaco[notmissing]FRA-LIL_21       -0.8594     0.423    0.470     0.499 -1.721
wruaco[notmissing]FRA-STR_21       -0.9144     0.401    0.440     0.464 -1.973
wruaco[notmissing]FRA-TOU_21       -1.1735     0.309    0.525     0.557 -2.109
wruaco[notmissing]SWE-NSW_02       -0.0290     0.971    0.276     0.308 -0.094
wruaco[notmissing]SWE-NSW_03        0.0790     1.082    0.257     0.279  0.283
wruaco[notmissing]UNK-BEL_21       -0.7772     0.460    0.358     0.376 -2.070
                                       p
allele[notmissing]                 0.460
wz[notmissing, selectedcovariates] 0.018
wruaco[notmissing]FIN-EAS_03       0.340
wruaco[notmissing]FIN-EAS_24       0.530
wruaco[notmissing]FIN-WES_03       0.410
wruaco[notmissing]FIN-WES_24       0.330
wruaco[notmissing]FRA-LIL_21       0.085
wruaco[notmissing]FRA-STR_21       0.049
wruaco[notmissing]FRA-TOU_21       0.035
wruaco[notmissing]SWE-NSW_02       0.930
wruaco[notmissing]SWE-NSW_03       0.780
wruaco[notmissing]UNK-BEL_21       0.038

                                   exp(coef) exp(-coef) lower .95 upper .95
allele[notmissing]                     0.816      1.225     0.476     1.399
wz[notmissing, selectedcovariates]     1.369      0.731     1.055     1.775
wruaco[notmissing]FIN-EAS_03           1.243      0.805     0.794     1.945
wruaco[notmissing]FIN-EAS_24           0.877      1.140     0.585     1.315
wruaco[notmissing]FIN-WES_03           0.815      1.227     0.503     1.321
wruaco[notmissing]FIN-WES_24           0.801      1.248     0.514     1.250
wruaco[notmissing]FRA-LIL_21           0.423      2.362     0.159     1.127
wruaco[notmissing]FRA-STR_21           0.401      2.495     0.162     0.994
wruaco[notmissing]FRA-TOU_21           0.309      3.233     0.104     0.921
wruaco[notmissing]SWE-NSW_02           0.971      1.029     0.531     1.776
wruaco[notmissing]SWE-NSW_03           1.082      0.924     0.626     1.871
wruaco[notmissing]UNK-BEL_21           0.460      2.175     0.220     0.960

Rsquare= 0.015   (max possible= 0.924 )
Likelihood ratio test= 37.3  on 12 df,   p=0.000198
Wald test            = 31.8  on 12 df,   p=0.00146
Score (logrank) test = 35.7  on 12 df,   p=0.000360,   Robust = 33.2  p=0.000887

  (Note: the likelihood ratio and score tests assume independence of
     observations within a cluster, the Wald and robust score tests do not).

Updated on 2008-06-04