response: (stroke4 %in% c('1','2','3','4','5','6'))
covariates: nonhdl hdla bmi bpm dsmoker hisdiab1
SNP: 10Q11_21_MG_458
Call:
coxph(formula = y[notmissing] ~ allele[notmissing] + wz[notmissing,
selectedcovariates] + wruaco[notmissing] + strata(wsex[notmissing]) +
cluster(wdata$id[notmissing]), weights = weight[notmissing],
robust = TRUE)
n=2434 (43 observations deleted due to missingness)
coef exp(coef) se(coef) robust se
allele[notmissing] 0.17730 1.194 0.09911 0.10850
wz[notmissing, selectedcovariates]1 0.06778 1.070 0.04397 0.05205
wz[notmissing, selectedcovariates]2 -0.75112 0.472 0.17492 0.19955
wz[notmissing, selectedcovariates]3 -0.00288 0.997 0.01224 0.01353
wz[notmissing, selectedcovariates]4 0.01668 1.017 0.00368 0.00424
wz[notmissing, selectedcovariates]5 0.35971 1.433 0.12454 0.13948
wz[notmissing, selectedcovariates]6 0.77707 2.175 0.15843 0.19766
wruaco[notmissing]FIN-EAS_03 0.26082 1.298 0.21480 0.23547
wruaco[notmissing]FIN-EAS_24 -0.22703 0.797 0.19240 0.22268
wruaco[notmissing]FIN-WES_03 -0.10932 0.896 0.22390 0.24366
wruaco[notmissing]FIN-WES_24 -0.25047 0.778 0.20510 0.24287
wruaco[notmissing]FRA-LIL_21 -1.08949 0.336 0.52019 0.57199
wruaco[notmissing]FRA-STR_21 -1.17181 0.310 0.47807 0.52262
wruaco[notmissing]FRA-TOU_21 -0.77357 0.461 0.52837 0.57084
wruaco[notmissing]SWE-NSW_02 -0.13847 0.871 0.29879 0.35900
wruaco[notmissing]SWE-NSW_03 0.05618 1.058 0.26185 0.29579
wruaco[notmissing]UNK-BEL_21 -0.74488 0.475 0.35941 0.38131
z p
allele[notmissing] 1.634 1.0e-01
wz[notmissing, selectedcovariates]1 1.302 1.9e-01
wz[notmissing, selectedcovariates]2 -3.764 1.7e-04
wz[notmissing, selectedcovariates]3 -0.213 8.3e-01
wz[notmissing, selectedcovariates]4 3.934 8.3e-05
wz[notmissing, selectedcovariates]5 2.579 9.9e-03
wz[notmissing, selectedcovariates]6 3.931 8.4e-05
wruaco[notmissing]FIN-EAS_03 1.108 2.7e-01
wruaco[notmissing]FIN-EAS_24 -1.020 3.1e-01
wruaco[notmissing]FIN-WES_03 -0.449 6.5e-01
wruaco[notmissing]FIN-WES_24 -1.031 3.0e-01
wruaco[notmissing]FRA-LIL_21 -1.905 5.7e-02
wruaco[notmissing]FRA-STR_21 -2.242 2.5e-02
wruaco[notmissing]FRA-TOU_21 -1.355 1.8e-01
wruaco[notmissing]SWE-NSW_02 -0.386 7.0e-01
wruaco[notmissing]SWE-NSW_03 0.190 8.5e-01
wruaco[notmissing]UNK-BEL_21 -1.954 5.1e-02
exp(coef) exp(-coef) lower .95 upper .95
allele[notmissing] 1.194 0.838 0.965 1.477
wz[notmissing, selectedcovariates]1 1.070 0.934 0.966 1.185
wz[notmissing, selectedcovariates]2 0.472 2.119 0.319 0.698
wz[notmissing, selectedcovariates]3 0.997 1.003 0.971 1.024
wz[notmissing, selectedcovariates]4 1.017 0.983 1.008 1.025
wz[notmissing, selectedcovariates]5 1.433 0.698 1.090 1.883
wz[notmissing, selectedcovariates]6 2.175 0.460 1.476 3.204
wruaco[notmissing]FIN-EAS_03 1.298 0.770 0.818 2.059
wruaco[notmissing]FIN-EAS_24 0.797 1.255 0.515 1.233
wruaco[notmissing]FIN-WES_03 0.896 1.116 0.556 1.445
wruaco[notmissing]FIN-WES_24 0.778 1.285 0.484 1.253
wruaco[notmissing]FRA-LIL_21 0.336 2.973 0.110 1.032
wruaco[notmissing]FRA-STR_21 0.310 3.228 0.111 0.863
wruaco[notmissing]FRA-TOU_21 0.461 2.167 0.151 1.412
wruaco[notmissing]SWE-NSW_02 0.871 1.149 0.431 1.760
wruaco[notmissing]SWE-NSW_03 1.058 0.945 0.592 1.889
wruaco[notmissing]UNK-BEL_21 0.475 2.106 0.225 1.002
Rsquare= 0.046 (max possible= 0.927 )
Likelihood ratio test= 115 on 17 df, p=1.11e-16
Wald test = 86 on 17 df, p=3.16e-11
Score (logrank) test = 116 on 17 df, p=1.11e-16, Robust = 76.3 p=1.74e-09
(Note: the likelihood ratio and score tests assume independence of
observations within a cluster, the Wald and robust score tests do not).
Updated on 2008-06-04