response: (stroke4 %in% c('1','2','3','4','5','6'))
covariates: dsmoker
SNP: MTHFD1L_MG_449
Call:
coxph(formula = y[notmissing] ~ allele[notmissing] + wz[notmissing,
selectedcovariates] + wruaco[notmissing] + strata(wsex[notmissing]) +
cluster(wdata$id[notmissing]), weights = weight[notmissing],
robust = TRUE)
n= 2497
coef exp(coef) se(coef) robust se z
allele[notmissing] -0.2326 0.792 0.240 0.274 -0.848
wz[notmissing, selectedcovariates] 0.3004 1.350 0.121 0.133 2.265
wruaco[notmissing]FIN-EAS_03 0.2140 1.239 0.211 0.227 0.941
wruaco[notmissing]FIN-EAS_24 -0.1652 0.848 0.182 0.206 -0.800
wruaco[notmissing]FIN-WES_03 -0.1240 0.883 0.223 0.240 -0.516
wruaco[notmissing]FIN-WES_24 -0.2508 0.778 0.197 0.226 -1.108
wruaco[notmissing]FRA-LIL_21 -0.9067 0.404 0.469 0.499 -1.819
wruaco[notmissing]FRA-STR_21 -0.9590 0.383 0.439 0.463 -2.073
wruaco[notmissing]FRA-TOU_21 -1.2165 0.296 0.525 0.556 -2.189
wruaco[notmissing]SWE-NSW_02 -0.0689 0.933 0.276 0.309 -0.223
wruaco[notmissing]SWE-NSW_03 0.0496 1.051 0.256 0.280 0.177
wruaco[notmissing]UNK-BEL_21 -0.8153 0.443 0.357 0.374 -2.178
p
allele[notmissing] 0.400
wz[notmissing, selectedcovariates] 0.024
wruaco[notmissing]FIN-EAS_03 0.350
wruaco[notmissing]FIN-EAS_24 0.420
wruaco[notmissing]FIN-WES_03 0.610
wruaco[notmissing]FIN-WES_24 0.270
wruaco[notmissing]FRA-LIL_21 0.069
wruaco[notmissing]FRA-STR_21 0.038
wruaco[notmissing]FRA-TOU_21 0.029
wruaco[notmissing]SWE-NSW_02 0.820
wruaco[notmissing]SWE-NSW_03 0.860
wruaco[notmissing]UNK-BEL_21 0.029
exp(coef) exp(-coef) lower .95 upper .95
allele[notmissing] 0.792 1.262 0.4629 1.357
wz[notmissing, selectedcovariates] 1.350 0.740 1.0413 1.751
wruaco[notmissing]FIN-EAS_03 1.239 0.807 0.7933 1.934
wruaco[notmissing]FIN-EAS_24 0.848 1.180 0.5656 1.271
wruaco[notmissing]FIN-WES_03 0.883 1.132 0.5517 1.414
wruaco[notmissing]FIN-WES_24 0.778 1.285 0.4994 1.213
wruaco[notmissing]FRA-LIL_21 0.404 2.476 0.1520 1.073
wruaco[notmissing]FRA-STR_21 0.383 2.609 0.1548 0.949
wruaco[notmissing]FRA-TOU_21 0.296 3.375 0.0997 0.881
wruaco[notmissing]SWE-NSW_02 0.933 1.071 0.5095 1.710
wruaco[notmissing]SWE-NSW_03 1.051 0.952 0.6075 1.818
wruaco[notmissing]UNK-BEL_21 0.443 2.260 0.2125 0.922
Rsquare= 0.016 (max possible= 0.928 )
Likelihood ratio test= 39.4 on 12 df, p=9.18e-05
Wald test = 32.9 on 12 df, p=0.00099
Score (logrank) test = 37.5 on 12 df, p=0.000188, Robust = 34.5 p=0.000552
(Note: the likelihood ratio and score tests assume independence of
observations within a cluster, the Wald and robust score tests do not).
Updated on 2008-06-04