response: (stroke4 %in% c('1','2','3','4','5','6'))
covariates: dsmoker
SNP: SMAD3_MG_452
Call:
coxph(formula = y[notmissing] ~ allele[notmissing] + wz[notmissing,
selectedcovariates] + wruaco[notmissing] + strata(wsex[notmissing]) +
cluster(wdata$id[notmissing]), weights = weight[notmissing],
robust = TRUE)
n= 2496
coef exp(coef) se(coef) robust se z
allele[notmissing] 0.0342 1.035 0.0826 0.0936 0.365
wz[notmissing, selectedcovariates] 0.2964 1.345 0.1208 0.1325 2.237
wruaco[notmissing]FIN-EAS_03 0.2225 1.249 0.2115 0.2277 0.977
wruaco[notmissing]FIN-EAS_24 -0.1616 0.851 0.1817 0.2064 -0.783
wruaco[notmissing]FIN-WES_03 -0.1241 0.883 0.2227 0.2396 -0.518
wruaco[notmissing]FIN-WES_24 -0.2579 0.773 0.1964 0.2254 -1.144
wruaco[notmissing]FRA-LIL_21 -0.9285 0.395 0.4702 0.5016 -1.851
wruaco[notmissing]FRA-STR_21 -0.9580 0.384 0.4392 0.4638 -2.065
wruaco[notmissing]FRA-TOU_21 -1.2059 0.299 0.5246 0.5557 -2.170
wruaco[notmissing]SWE-NSW_02 -0.0753 0.927 0.2765 0.3113 -0.242
wruaco[notmissing]SWE-NSW_03 0.0484 1.050 0.2560 0.2788 0.173
wruaco[notmissing]UNK-BEL_21 -0.8280 0.437 0.3575 0.3749 -2.208
p
allele[notmissing] 0.710
wz[notmissing, selectedcovariates] 0.025
wruaco[notmissing]FIN-EAS_03 0.330
wruaco[notmissing]FIN-EAS_24 0.430
wruaco[notmissing]FIN-WES_03 0.600
wruaco[notmissing]FIN-WES_24 0.250
wruaco[notmissing]FRA-LIL_21 0.064
wruaco[notmissing]FRA-STR_21 0.039
wruaco[notmissing]FRA-TOU_21 0.030
wruaco[notmissing]SWE-NSW_02 0.810
wruaco[notmissing]SWE-NSW_03 0.860
wruaco[notmissing]UNK-BEL_21 0.027
exp(coef) exp(-coef) lower .95 upper .95
allele[notmissing] 1.035 0.966 0.861 1.243
wz[notmissing, selectedcovariates] 1.345 0.743 1.037 1.744
wruaco[notmissing]FIN-EAS_03 1.249 0.800 0.800 1.952
wruaco[notmissing]FIN-EAS_24 0.851 1.175 0.568 1.275
wruaco[notmissing]FIN-WES_03 0.883 1.132 0.552 1.413
wruaco[notmissing]FIN-WES_24 0.773 1.294 0.497 1.202
wruaco[notmissing]FRA-LIL_21 0.395 2.531 0.148 1.056
wruaco[notmissing]FRA-STR_21 0.384 2.606 0.155 0.952
wruaco[notmissing]FRA-TOU_21 0.299 3.340 0.101 0.890
wruaco[notmissing]SWE-NSW_02 0.927 1.078 0.504 1.707
wruaco[notmissing]SWE-NSW_03 1.050 0.953 0.608 1.813
wruaco[notmissing]UNK-BEL_21 0.437 2.289 0.210 0.911
Rsquare= 0.015 (max possible= 0.928 )
Likelihood ratio test= 38.5 on 12 df, p=0.000125
Wald test = 32.4 on 12 df, p=0.00122
Score (logrank) test = 36.7 on 12 df, p=0.000248, Robust = 34 p=0.000668
(Note: the likelihood ratio and score tests assume independence of
observations within a cluster, the Wald and robust score tests do not).
Updated on 2008-06-04