Linear regression for non-HDL cholesterol (NONHDL), test for additive allele effects, subcohort without individuals on cholesterol treatment

Rank SNP name in MORGAM RS-code Chromosome Success Genotype N Mean coef (95% CI) nominal p-value tail-area FDR
1 SMAD3_MG_452 rs17228212 15 99.2% C/C 97 4.893 0.123
(0.039, 0.206)		 0.00407 0.15319
C/T 663 4.672
T/T 1049 4.575
2 PSRC1_MG_460 rs599839 1 99.5% A/A 1037 4.683 0.109
(0.029, 0.188)		 0.00729 0.15319
A/G 658 4.558
G/G 119 4.506
3 19Q12_MG_446 rs7250581 19 98.0% A/A 44 4.808 0.105
(0.006, 0.204)		 0.03760 0.52271
A/G 419 4.694
G/G 1325 4.602
4 19Q12_MG_422 rs11670734 19 99.6% C/C 138 4.658 0.078
(-0.001, 0.156)		 0.05363 0.52271
C/G 749 4.674
G/G 930 4.585
5 SMAD3_MG_431 rs1866317 15 99.6% C/C 29 4.754 -0.096
(-0.200, 0.007)		 0.06891 0.52271
C/G 425 4.540
G/G 1363 4.651
6 CELSR2_MG_438 rs4970834 1 99.6% C/C 1130 4.666 0.078
(-0.008, 0.163)		 0.07533 0.52271
C/T 607 4.558
T/T 79 4.578
7 CELSR2_MG_434 rs413380 1 99.6% C/C 1652 4.640 0.137
(-0.020, 0.294)		 0.08712 0.52271
C/T 155 4.522
T/T 10 4.065
8 9P21_3_MG_451 rs1537378 9 98.3% A/A 267 4.628 -0.055
(-0.128, 0.017)		 0.13370 0.70190
A/G 878 4.583
G/G 648 4.680
9 1Q31_2_MG_453 rs1936982 1 99.1% C/C 227 4.609 0.052
(-0.020, 0.124)		 0.15823 0.73840
C/T 784 4.691
T/T 796 4.571
10 SEZ6L_MG_457 rs6005016 22 99.0% A/A 4 4.203 -0.121
(-0.307, 0.066)		 0.20503 0.77233
A/G 121 4.571
G/G 1680 4.633
11 SMAD3_MG_424 rs12913547 15 99.7% C/C 127 4.513 -0.051
(-0.130, 0.028)		 0.20511 0.77233
C/T 706 4.602
T/T 985 4.659
12 5Q21_1_MG_435 rs436495 5 98.9% A/A 111 4.704 0.050
(-0.031, 0.132)		 0.22232 0.77233
A/G 639 4.679
G/G 1054 4.599
13 9P21_3_MG_459 rs7865618 9 98.9% A/A 591 4.670 0.035
(-0.035, 0.106)		 0.32847 0.77233
A/G 881 4.597
G/G 332 4.630
14 MTHFD1L_MG_449 rs12214306 6 99.2% C/C 1 2.970 -0.112
(-0.343, 0.120)		 0.34544 0.77233
C/T 82 4.549
T/T 1727 4.632
15 9P21_3_MG_437 rs496892 9 99.2% C/C 460 4.687 0.032
(-0.038, 0.103)		 0.36801 0.77233
C/T 933 4.591
T/T 416 4.640
16 MIA3_MG_430 rs17465637 1 99.3% A/A 139 4.697 0.033
(-0.045, 0.110)		 0.40879 0.77233
A/C 664 4.646
C/C 1008 4.606
17 10Q11_21_MG_432 rs2146807 10 99.4% C/C 14 4.391 -0.050
(-0.174, 0.074)		 0.42555 0.77233
C/T 289 4.610
T/T 1510 4.633
18 2Q36_3_MG_433 rs2972147 2 98.6% C/C 721 4.644 0.029
(-0.043, 0.101)		 0.43344 0.77233
C/T 828 4.620
T/T 249 4.574
19 10Q11_21_MG_439 rs501120 10 96.7% C/C 43 4.679 0.039
(-0.060, 0.138)		 0.43818 0.77233
C/T 431 4.655
T/T 1289 4.618
20 SEZ6L_MG_444 rs688034 22 99.6% C/C 937 4.600 -0.028
(-0.108, 0.051)		 0.48668 0.77233
C/T 752 4.649
T/T 127 4.688
21 MTHFD1L_MG_423 rs12525353 6 99.5% A/A 2 5.800 -0.082
(-0.328, 0.163)		 0.51027 0.77233
A/C 68 4.453
C/C 1745 4.632
22 2Q36_3_MG_447 rs7597168 2 99.5% C/C 1015 4.652 0.027
(-0.054, 0.109)		 0.51034 0.77233
C/T 697 4.584
T/T 103 4.645
23 SEZ6L_MG_426 rs137205 22 99.6% A/A 147 4.572 0.026
(-0.052, 0.104)		 0.51300 0.77233
A/G 787 4.679
G/G 882 4.591
24 9P21_3_MG_420 rs10738610 9 99.2% A/A 603 4.668 0.022
(-0.049, 0.094)		 0.53912 0.77233
A/C 895 4.582
C/C 312 4.672
25 12Q12_MG_448 rs7970834 12 99.7% G/G 555 4.602 -0.022
(-0.093, 0.050)		 0.55010 0.77233
G/T 923 4.644
T/T 340 4.621
26 2Q36_3_MG_461 rs2943634 2 97.7% A/A 228 4.591 -0.022
(-0.094, 0.051)		 0.55898 0.77233
A/C 809 4.620
C/C 745 4.643
27 5Q21_1_MG_436 rs449650 5 99.1% G/G 1126 4.608 -0.023
(-0.106, 0.060)		 0.58065 0.77233
G/T 583 4.654
T/T 98 4.710
28 MIA3_MG_454 rs3008621 1 98.7% A/A 47 4.719 0.027
(-0.070, 0.125)		 0.58236 0.77233
A/G 436 4.633
G/G 1317 4.622
29 5Q21_1_MG_455 rs383830 5 99.1% A/A 96 4.691 0.022
(-0.061, 0.106)		 0.59929 0.77233
A/T 586 4.658
T/T 1126 4.607
30 SEZ6L_MG_442 rs6005015 22 99.6% C/C 164 4.554 -0.020
(-0.096, 0.056)		 0.61078 0.77233
C/T 795 4.624
T/T 858 4.638
31 10Q11_21_MG_456 rs513391 10 99.2% A/A 1275 4.620 -0.022
(-0.118, 0.073)		 0.64451 0.77233
A/C 489 4.642
C/C 45 4.667
32 5Q21_1_MG_441 rs565928 5 99.6% C/C 1129 4.610 -0.018
(-0.101, 0.065)		 0.67288 0.77233
C/T 590 4.640
T/T 97 4.724
33 MTHFD1L_MG_445 rs6922269 6 99.4% A/A 96 4.492 -0.018
(-0.101, 0.065)		 0.67441 0.77233
A/G 636 4.649
G/G 1081 4.627
34 SEZ6L_MG_427 rs137209 22 99.7% A/A 191 4.586 0.016
(-0.059, 0.091)		 0.68026 0.77233
A/G 838 4.661
G/G 789 4.601
35 9P21_3_MG_425 rs1333049 9 99.7% C/C 302 4.703 -0.015
(-0.087, 0.057)		 0.68303 0.77233
C/G 897 4.566
G/G 619 4.678
36 10Q11_21_MG_429 rs1746049 10 99.6% C/C 1375 4.630 0.021
(-0.084, 0.126)		 0.69482 0.77233
C/T 415 4.630
T/T 27 4.478
37 10Q11_21_MG_443 rs687175 10 99.6% C/C 44 4.647 0.019
(-0.077, 0.114)		 0.70106 0.77233
C/T 491 4.642
T/T 1281 4.621
38 10Q11_21_MG_440 rs559580 10 99.1% C/C 44 4.647 0.017
(-0.079, 0.113)		 0.72648 0.77233
C/T 486 4.643
T/T 1278 4.621
39 9P21_3_MG_421 rs10757283 9 99.6% C/C 526 4.650 -0.012
(-0.083, 0.059)		 0.73866 0.77233
C/T 915 4.615
T/T 375 4.622
40 10Q11_21_MG_458 rs622472 10 98.5% A/A 1261 4.620 -0.016
(-0.111, 0.079)		 0.74293 0.77233
A/C 489 4.642
C/C 46 4.648
41 FMN2_MG_450 rs1456648 1 98.6% G/G 42 4.486 -0.016
(-0.113, 0.082)		 0.75394 0.77233
G/T 469 4.632
T/T 1288 4.632
42 10Q11_21_MG_428 rs1746048 10 99.6% C/C 1284 4.624 -0.011
(-0.107, 0.084)		 0.81942 0.81942
C/T 489 4.636
T/T 44 4.647

adjusted for: cohort age1 sex

Updated on 2008-12-08