| rank | SNP | RS-code | Chromosome | Success | Genotype | Cases | Non-cases | Total | HR (95% CI) | nominal p-value | tail-area FDR |
|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | 9P21_3_MG_425 | rs1333049 | 9 | 99.6% | C/C | 79 (19%) | 337 (17%) | 416 | 1.147 (0.985, 1.335) |
0.07695 | 0.93820 |
| C/G | 209 (49%) | 974 (49%) | 1183 | ||||||||
| G/G | 137 (32%) | 681 (34%) | 818 | ||||||||
| 2 | 19Q12_MG_422 | rs11670734 | 19 | 99.5% | C/C | 38 (9%) | 154 (8%) | 192 | 1.157 (0.975, 1.373) |
0.09488 | 0.93820 |
| C/G | 173 (41%) | 810 (41%) | 983 | ||||||||
| G/G | 214 (50%) | 1027 (52%) | 1241 | ||||||||
| 3 | 9P21_3_MG_420 | rs10738610 | 9 | 99.1% | A/A | 134 (32%) | 664 (33%) | 798 | 0.879 (0.755, 1.024) |
0.09754 | 0.93820 |
| A/C | 208 (49%) | 973 (49%) | 1181 | ||||||||
| C/C | 80 (19%) | 347 (17%) | 427 | ||||||||
| 4 | 9P21_3_MG_421 | rs10757283 | 9 | 99.3% | C/C | 108 (25%) | 579 (29%) | 687 | 0.896 (0.769, 1.044) |
0.15842 | 0.93820 |
| C/T | 217 (51%) | 1006 (51%) | 1223 | ||||||||
| T/T | 99 (23%) | 401 (20%) | 500 | ||||||||
| 5 | MTHFD1L_MG_423 | rs12525353 | 6 | 99.4% | A/A | 0 (0%) | 2 (0%) | 2 | 0.649 (0.356, 1.184) |
0.15882 | 0.93820 |
| A/C | 12 (3%) | 78 (4%) | 90 | ||||||||
| C/C | 412 (97%) | 1909 (96%) | 2321 | ||||||||
| 6 | FMN2_MG_450 | rs1456648 | 1 | 98.6% | G/G | 13 (3%) | 47 (2%) | 60 | 0.864 (0.694, 1.076) |
0.19077 | 0.93820 |
| G/T | 91 (22%) | 511 (26%) | 602 | ||||||||
| T/T | 316 (75%) | 1414 (72%) | 1730 | ||||||||
| 7 | SEZ6L_MG_427 | rs137209 | 22 | 99.6% | A/A | 45 (11%) | 198 (10%) | 243 | 0.900 (0.757, 1.069) |
0.22964 | 0.93820 |
| A/G | 170 (40%) | 922 (46%) | 1092 | ||||||||
| G/G | 210 (49%) | 872 (44%) | 1082 | ||||||||
| 8 | 9P21_3_MG_451 | rs1537378 | 9 | 98.2% | A/A | 54 (13%) | 293 (15%) | 347 | 0.914 (0.785, 1.065) |
0.25060 | 0.93820 |
| A/G | 208 (49%) | 955 (49%) | 1163 | ||||||||
| G/G | 159 (38%) | 714 (36%) | 873 | ||||||||
| 9 | 10Q11_21_MG_458 | rs622472 | 10 | 98.4% | A/A | 300 (72%) | 1377 (70%) | 1677 | 1.128 (0.916, 1.390) |
0.25531 | 0.93820 |
| A/C | 110 (26%) | 537 (27%) | 647 | ||||||||
| C/C | 9 (2%) | 54 (3%) | 63 | ||||||||
| 10 | SEZ6L_MG_444 | rs688034 | 22 | 99.5% | C/C | 238 (56%) | 1038 (52%) | 1276 | 1.104 (0.924, 1.319) |
0.27743 | 0.93820 |
| C/T | 159 (38%) | 817 (41%) | 976 | ||||||||
| T/T | 27 (6%) | 135 (7%) | 162 | ||||||||
| 11 | 10Q11_21_MG_456 | rs513391 | 10 | 99.1% | A/A | 302 (72%) | 1393 (70%) | 1695 | 1.113 (0.903, 1.372) |
0.31353 | 0.93820 |
| A/C | 110 (26%) | 537 (27%) | 647 | ||||||||
| C/C | 9 (2%) | 53 (3%) | 62 | ||||||||
| 12 | 10Q11_21_MG_440 | rs559580 | 10 | 99.1% | C/C | 9 (2%) | 52 (3%) | 61 | 0.902 (0.732, 1.111) |
0.33234 | 0.93820 |
| C/T | 111 (26%) | 534 (27%) | 645 | ||||||||
| T/T | 304 (72%) | 1396 (70%) | 1700 | ||||||||
| 13 | SMAD3_MG_431 | rs1866317 | 15 | 99.5% | C/C | 9 (2%) | 30 (2%) | 39 | 1.112 (0.893, 1.384) |
0.34367 | 0.93820 |
| C/G | 108 (25%) | 470 (24%) | 578 | ||||||||
| G/G | 308 (72%) | 1491 (75%) | 1799 | ||||||||
| 14 | 10Q11_21_MG_443 | rs687175 | 10 | 99.5% | C/C | 9 (2%) | 52 (3%) | 61 | 0.905 (0.736, 1.115) |
0.34857 | 0.93820 |
| C/T | 112 (26%) | 539 (27%) | 651 | ||||||||
| T/T | 304 (72%) | 1398 (70%) | 1702 | ||||||||
| 15 | 10Q11_21_MG_432 | rs2146807 | 10 | 99.3% | C/C | 2 (0%) | 14 (1%) | 16 | 0.876 (0.657, 1.169) |
0.36987 | 0.93820 |
| C/T | 64 (15%) | 327 (16%) | 391 | ||||||||
| T/T | 359 (84%) | 1645 (83%) | 2004 | ||||||||
| 16 | 10Q11_21_MG_428 | rs1746048 | 10 | 99.5% | C/C | 304 (72%) | 1402 (70%) | 1706 | 1.097 (0.891, 1.351) |
0.38184 | 0.93820 |
| C/T | 112 (26%) | 537 (27%) | 649 | ||||||||
| T/T | 9 (2%) | 51 (3%) | 60 | ||||||||
| 17 | 10Q11_21_MG_439 | rs501120 | 10 | 96.7% | C/C | 9 (2%) | 51 (3%) | 60 | 0.910 (0.734, 1.128) |
0.38882 | 0.93820 |
| C/T | 99 (24%) | 479 (25%) | 578 | ||||||||
| T/T | 304 (74%) | 1405 (73%) | 1709 | ||||||||
| 18 | 9P21_3_MG_459 | rs7865618 | 9 | 98.8% | A/A | 136 (32%) | 639 (32%) | 775 | 1.062 (0.918, 1.230) |
0.41808 | 0.93820 |
| A/G | 216 (51%) | 974 (49%) | 1190 | ||||||||
| G/G | 69 (16%) | 365 (18%) | 434 | ||||||||
| 19 | MTHFD1L_MG_449 | rs12214306 | 6 | 99.1% | C/C | 1 (0%) | 1 (0%) | 2 | 0.816 (0.476, 1.399) |
0.46037 | 0.93820 |
| C/T | 16 (4%) | 93 (5%) | 109 | ||||||||
| T/T | 404 (96%) | 1891 (95%) | 2295 | ||||||||
| 20 | 19Q12_MG_446 | rs7250581 | 19 | 98.0% | A/A | 11 (3%) | 50 (3%) | 61 | 1.082 (0.874, 1.338) |
0.47026 | 0.93820 |
| A/G | 102 (24%) | 461 (24%) | 563 | ||||||||
| G/G | 306 (73%) | 1449 (74%) | 1755 | ||||||||
| 21 | 12Q12_MG_448 | rs7970834 | 12 | 99.5% | G/G | 127 (30%) | 619 (31%) | 746 | 0.946 (0.810, 1.106) |
0.48746 | 0.93820 |
| G/T | 215 (51%) | 1005 (51%) | 1220 | ||||||||
| T/T | 83 (20%) | 366 (18%) | 449 | ||||||||
| 22 | SEZ6L_MG_426 | rs137205 | 22 | 99.5% | A/A | 38 (9%) | 150 (8%) | 188 | 0.940 (0.787, 1.122) |
0.49144 | 0.93820 |
| A/G | 161 (38%) | 861 (43%) | 1022 | ||||||||
| G/G | 226 (53%) | 979 (49%) | 1205 | ||||||||
| 23 | MIA3_MG_454 | rs3008621 | 1 | 98.5% | A/A | 11 (3%) | 51 (3%) | 62 | 0.940 (0.759, 1.163) |
0.56733 | 0.99666 |
| A/G | 101 (24%) | 477 (24%) | 578 | ||||||||
| G/G | 307 (73%) | 1444 (73%) | 1751 | ||||||||
| 24 | CELSR2_MG_434 | rs413380 | 1 | 99.5% | C/C | 389 (92%) | 1807 (91%) | 2196 | 1.085 (0.770, 1.527) |
0.64148 | 0.99666 |
| C/T | 35 (8%) | 174 (9%) | 209 | ||||||||
| T/T | 1 (0%) | 10 (1%) | 11 | ||||||||
| 25 | 9P21_3_MG_437 | rs496892 | 9 | 99.0% | C/C | 103 (24%) | 491 (25%) | 594 | 1.034 (0.892, 1.198) |
0.66176 | 0.99666 |
| C/T | 227 (54%) | 1029 (52%) | 1256 | ||||||||
| T/T | 94 (22%) | 458 (23%) | 552 | ||||||||
| 26 | PSRC1_MG_460 | rs599839 | 1 | 99.4% | A/A | 242 (57%) | 1144 (57%) | 1386 | 1.039 (0.875, 1.233) |
0.66335 | 0.99666 |
| A/G | 159 (38%) | 721 (36%) | 880 | ||||||||
| G/G | 20 (5%) | 127 (6%) | 147 | ||||||||
| 27 | SMAD3_MG_424 | rs12913547 | 15 | 99.6% | C/C | 24 (6%) | 141 (7%) | 165 | 1.036 (0.879, 1.222) |
0.67307 | 0.99666 |
| C/T | 183 (43%) | 771 (39%) | 954 | ||||||||
| T/T | 218 (51%) | 1080 (54%) | 1298 | ||||||||
| 28 | 2Q36_3_MG_447 | rs7597168 | 2 | 99.4% | C/C | 241 (57%) | 1118 (56%) | 1359 | 1.027 (0.862, 1.225) |
0.76425 | 0.99666 |
| C/T | 159 (37%) | 758 (38%) | 917 | ||||||||
| T/T | 25 (6%) | 112 (6%) | 137 | ||||||||
| 29 | SEZ6L_MG_442 | rs6005015 | 22 | 99.5% | C/C | 39 (9%) | 179 (9%) | 218 | 0.975 (0.820, 1.159) |
0.77169 | 0.99666 |
| C/T | 177 (42%) | 859 (43%) | 1036 | ||||||||
| T/T | 209 (49%) | 953 (48%) | 1162 | ||||||||
| 30 | SMAD3_MG_452 | rs17228212 | 15 | 99.1% | C/C | 22 (5%) | 108 (5%) | 130 | 1.024 (0.851, 1.234) |
0.79938 | 0.99666 |
| C/T | 149 (35%) | 721 (36%) | 870 | ||||||||
| T/T | 250 (59%) | 1155 (58%) | 1405 | ||||||||
| 31 | 10Q11_21_MG_429 | rs1746049 | 10 | 99.5% | C/C | 323 (76%) | 1518 (76%) | 1841 | 1.029 (0.821, 1.288) |
0.80609 | 0.99666 |
| C/T | 96 (23%) | 440 (22%) | 536 | ||||||||
| T/T | 6 (1%) | 33 (2%) | 39 | ||||||||
| 32 | SEZ6L_MG_457 | rs6005016 | 22 | 98.9% | A/A | 2 (0%) | 3 (0%) | 5 | 1.047 (0.715, 1.534) |
0.81262 | 0.99666 |
| A/G | 28 (7%) | 138 (7%) | 166 | ||||||||
| G/G | 391 (93%) | 1839 (93%) | 2230 | ||||||||
| 33 | 2Q36_3_MG_433 | rs2972147 | 2 | 98.7% | C/C | 170 (40%) | 788 (40%) | 958 | 1.018 (0.872, 1.187) |
0.82495 | 0.99666 |
| C/T | 203 (48%) | 912 (46%) | 1115 | ||||||||
| T/T | 52 (12%) | 270 (14%) | 322 | ||||||||
| 34 | 5Q21_1_MG_435 | rs436495 | 5 | 98.8% | A/A | 30 (7%) | 116 (6%) | 146 | 0.983 (0.823, 1.174) |
0.85217 | 0.99666 |
| A/G | 139 (33%) | 691 (35%) | 830 | ||||||||
| G/G | 252 (60%) | 1169 (59%) | 1421 | ||||||||
| 35 | CELSR2_MG_438 | rs4970834 | 1 | 99.5% | C/C | 268 (63%) | 1240 (62%) | 1508 | 1.011 (0.836, 1.222) |
0.91123 | 0.99666 |
| C/T | 138 (32%) | 666 (33%) | 804 | ||||||||
| T/T | 19 (4%) | 83 (4%) | 102 | ||||||||
| 36 | 5Q21_1_MG_441 | rs565928 | 5 | 99.5% | C/C | 266 (63%) | 1249 (63%) | 1515 | 1.010 (0.846, 1.206) |
0.91365 | 0.99666 |
| C/T | 136 (32%) | 637 (32%) | 773 | ||||||||
| T/T | 23 (5%) | 104 (5%) | 127 | ||||||||
| 37 | MTHFD1L_MG_445 | rs6922269 | 6 | 99.4% | A/A | 28 (7%) | 105 (5%) | 133 | 1.008 (0.834, 1.218) |
0.93593 | 0.99666 |
| A/G | 135 (32%) | 698 (35%) | 833 | ||||||||
| G/G | 262 (62%) | 1184 (60%) | 1446 | ||||||||
| 38 | MIA3_MG_430 | rs17465637 | 1 | 99.2% | A/A | 36 (8%) | 148 (7%) | 184 | 1.003 (0.845, 1.192) |
0.96903 | 0.99666 |
| A/C | 149 (35%) | 735 (37%) | 884 | ||||||||
| C/C | 239 (56%) | 1101 (55%) | 1340 | ||||||||
| 39 | 5Q21_1_MG_436 | rs449650 | 5 | 99.1% | G/G | 264 (62%) | 1248 (63%) | 1512 | 1.003 (0.840, 1.197) |
0.97505 | 0.99666 |
| G/T | 136 (32%) | 628 (32%) | 764 | ||||||||
| T/T | 23 (5%) | 105 (5%) | 128 | ||||||||
| 40 | 1Q31_2_MG_453 | rs1936982 | 1 | 99.0% | C/C | 49 (12%) | 258 (13%) | 307 | 0.998 (0.856, 1.164) |
0.98170 | 0.99666 |
| C/T | 193 (46%) | 860 (43%) | 1053 | ||||||||
| T/T | 179 (43%) | 864 (44%) | 1043 | ||||||||
| 41 | 2Q36_3_MG_461 | rs2943634 | 2 | 97.3% | A/A | 50 (12%) | 246 (13%) | 296 | 0.999 (0.851, 1.171) |
0.98750 | 0.99666 |
| A/C | 187 (46%) | 893 (46%) | 1080 | ||||||||
| C/C | 172 (42%) | 813 (42%) | 985 | ||||||||
| 42 | 5Q21_1_MG_455 | rs383830 | 5 | 99.0% | A/A | 23 (5%) | 103 (5%) | 126 | 1.000 (0.837, 1.194) |
0.99666 | 0.99666 |
| A/T | 135 (32%) | 631 (32%) | 766 | ||||||||
| T/T | 263 (62%) | 1248 (63%) | 1511 |
Updated on 2008-12-08
