| rank | SNP | RS-code | Chromosome | Success | Genotype | Cases | Non-cases | Total | HR (95% CI) | nominal p-value | tail-area FDR |
|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | 19Q12_MG_422 | rs11670734 | 19 | 99.5% | C/C | 39 (9%) | 153 (8%) | 192 | 1.162 (0.982, 1.376) |
0.08112 | 0.78556 |
| C/G | 179 (41%) | 809 (41%) | 988 | ||||||||
| G/G | 219 (50%) | 1026 (52%) | 1245 | ||||||||
| 2 | 9P21_3_MG_425 | rs1333049 | 9 | 99.6% | C/C | 82 (19%) | 335 (17%) | 417 | 1.143 (0.983, 1.329) |
0.08271 | 0.78556 |
| C/G | 212 (49%) | 973 (49%) | 1185 | ||||||||
| G/G | 143 (33%) | 681 (34%) | 824 | ||||||||
| 3 | 9P21_3_MG_420 | rs10738610 | 9 | 99.1% | A/A | 140 (32%) | 664 (34%) | 804 | 0.882 (0.758, 1.026) |
0.10456 | 0.78556 |
| A/C | 211 (49%) | 972 (49%) | 1183 | ||||||||
| C/C | 83 (19%) | 345 (17%) | 428 | ||||||||
| 4 | MTHFD1L_MG_423 | rs12525353 | 6 | 99.4% | A/A | 0 (0%) | 2 (0%) | 2 | 0.635 (0.348, 1.158) |
0.13842 | 0.78556 |
| A/C | 12 (3%) | 78 (4%) | 90 | ||||||||
| C/C | 424 (97%) | 1906 (96%) | 2330 | ||||||||
| 5 | FMN2_MG_450 | rs1456648 | 1 | 98.5% | G/G | 13 (3%) | 47 (2%) | 60 | 0.850 (0.684, 1.057) |
0.14320 | 0.78556 |
| G/T | 93 (22%) | 511 (26%) | 604 | ||||||||
| T/T | 325 (75%) | 1411 (72%) | 1736 | ||||||||
| 6 | 9P21_3_MG_421 | rs10757283 | 9 | 99.3% | C/C | 110 (25%) | 579 (29%) | 689 | 0.895 (0.770, 1.040) |
0.14879 | 0.78556 |
| C/T | 225 (52%) | 1003 (51%) | 1228 | ||||||||
| T/T | 101 (23%) | 401 (20%) | 502 | ||||||||
| 7 | 10Q11_21_MG_458 | rs622472 | 10 | 98.3% | A/A | 310 (72%) | 1374 (70%) | 1684 | 1.154 (0.938, 1.420) |
0.17527 | 0.78556 |
| A/C | 111 (26%) | 537 (27%) | 648 | ||||||||
| C/C | 9 (2%) | 54 (3%) | 63 | ||||||||
| 8 | SEZ6L_MG_427 | rs137209 | 22 | 99.6% | A/A | 47 (11%) | 197 (10%) | 244 | 0.894 (0.752, 1.061) |
0.19919 | 0.78556 |
| A/G | 172 (39%) | 920 (46%) | 1092 | ||||||||
| G/G | 218 (50%) | 872 (44%) | 1090 | ||||||||
| 9 | 10Q11_21_MG_456 | rs513391 | 10 | 99.0% | A/A | 312 (72%) | 1390 (70%) | 1702 | 1.139 (0.925, 1.403) |
0.22017 | 0.78556 |
| A/C | 111 (26%) | 537 (27%) | 648 | ||||||||
| C/C | 9 (2%) | 53 (3%) | 62 | ||||||||
| 10 | 10Q11_21_MG_440 | rs559580 | 10 | 99.1% | C/C | 9 (2%) | 52 (3%) | 61 | 0.880 (0.715, 1.084) |
0.22893 | 0.78556 |
| C/T | 112 (26%) | 534 (27%) | 646 | ||||||||
| T/T | 315 (72%) | 1393 (70%) | 1708 | ||||||||
| 11 | 10Q11_21_MG_443 | rs687175 | 10 | 99.5% | C/C | 9 (2%) | 52 (3%) | 61 | 0.884 (0.719, 1.087) |
0.24170 | 0.78556 |
| C/T | 113 (26%) | 539 (27%) | 652 | ||||||||
| T/T | 315 (72%) | 1395 (70%) | 1710 | ||||||||
| 12 | 10Q11_21_MG_432 | rs2146807 | 10 | 99.3% | C/C | 2 (0%) | 14 (1%) | 16 | 0.846 (0.634, 1.129) |
0.25729 | 0.78556 |
| C/T | 64 (15%) | 327 (16%) | 391 | ||||||||
| T/T | 371 (85%) | 1642 (83%) | 2013 | ||||||||
| 13 | 10Q11_21_MG_428 | rs1746048 | 10 | 99.5% | C/C | 315 (72%) | 1399 (70%) | 1714 | 1.125 (0.914, 1.384) |
0.26722 | 0.78556 |
| C/T | 113 (26%) | 537 (27%) | 650 | ||||||||
| T/T | 9 (2%) | 51 (3%) | 60 | ||||||||
| 14 | 10Q11_21_MG_439 | rs501120 | 10 | 96.7% | C/C | 9 (2%) | 51 (3%) | 60 | 0.889 (0.718, 1.101) |
0.27969 | 0.78556 |
| C/T | 100 (24%) | 479 (25%) | 579 | ||||||||
| T/T | 315 (74%) | 1402 (73%) | 1717 | ||||||||
| 15 | 9P21_3_MG_451 | rs1537378 | 9 | 98.2% | A/A | 56 (13%) | 293 (15%) | 349 | 0.922 (0.793, 1.072) |
0.29119 | 0.78556 |
| A/G | 214 (50%) | 954 (49%) | 1168 | ||||||||
| G/G | 162 (38%) | 712 (36%) | 874 | ||||||||
| 16 | SEZ6L_MG_444 | rs688034 | 22 | 99.5% | C/C | 244 (56%) | 1038 (52%) | 1282 | 1.098 (0.921, 1.309) |
0.29926 | 0.78556 |
| C/T | 164 (38%) | 814 (41%) | 978 | ||||||||
| T/T | 28 (6%) | 135 (7%) | 163 | ||||||||
| 17 | 12Q12_MG_448 | rs7970834 | 12 | 99.5% | G/G | 128 (29%) | 619 (31%) | 747 | 0.928 (0.796, 1.082) |
0.33892 | 0.83732 |
| G/T | 223 (51%) | 1002 (50%) | 1225 | ||||||||
| T/T | 86 (20%) | 366 (18%) | 452 | ||||||||
| 18 | SMAD3_MG_431 | rs1866317 | 15 | 99.5% | C/C | 9 (2%) | 30 (2%) | 39 | 1.102 (0.888, 1.368) |
0.37851 | 0.83764 |
| C/G | 111 (25%) | 469 (24%) | 580 | ||||||||
| G/G | 317 (73%) | 1489 (75%) | 1806 | ||||||||
| 19 | MTHFD1L_MG_449 | rs12214306 | 6 | 99.1% | C/C | 1 (0%) | 1 (0%) | 2 | 0.792 (0.463, 1.357) |
0.39634 | 0.83764 |
| C/T | 16 (4%) | 93 (5%) | 109 | ||||||||
| T/T | 415 (96%) | 1888 (95%) | 2303 | ||||||||
| 20 | 19Q12_MG_446 | rs7250581 | 19 | 98.0% | A/A | 12 (3%) | 49 (3%) | 61 | 1.094 (0.887, 1.349) |
0.40255 | 0.83764 |
| A/G | 105 (24%) | 461 (24%) | 566 | ||||||||
| G/G | 314 (73%) | 1447 (74%) | 1761 | ||||||||
| 21 | SEZ6L_MG_426 | rs137205 | 22 | 99.5% | A/A | 39 (9%) | 150 (8%) | 189 | 0.930 (0.781, 1.109) |
0.41882 | 0.83764 |
| A/G | 164 (38%) | 858 (43%) | 1022 | ||||||||
| G/G | 234 (54%) | 979 (49%) | 1213 | ||||||||
| 22 | 9P21_3_MG_459 | rs7865618 | 9 | 98.8% | A/A | 138 (32%) | 637 (32%) | 775 | 1.053 (0.912, 1.217) |
0.47890 | 0.91427 |
| A/G | 223 (52%) | 973 (49%) | 1196 | ||||||||
| G/G | 71 (16%) | 365 (18%) | 436 | ||||||||
| 23 | MIA3_MG_454 | rs3008621 | 1 | 98.5% | A/A | 11 (3%) | 51 (3%) | 62 | 0.945 (0.766, 1.166) |
0.59631 | 0.94139 |
| A/G | 105 (24%) | 475 (24%) | 580 | ||||||||
| G/G | 314 (73%) | 1443 (73%) | 1757 | ||||||||
| 24 | CELSR2_MG_434 | rs413380 | 1 | 99.5% | C/C | 400 (92%) | 1804 (91%) | 2204 | 1.088 (0.776, 1.526) |
0.62457 | 0.94139 |
| C/T | 36 (8%) | 174 (9%) | 210 | ||||||||
| T/T | 1 (0%) | 10 (1%) | 11 | ||||||||
| 25 | PSRC1_MG_460 | rs599839 | 1 | 99.4% | A/A | 249 (58%) | 1142 (57%) | 1391 | 1.042 (0.880, 1.235) |
0.63122 | 0.94139 |
| A/G | 164 (38%) | 720 (36%) | 884 | ||||||||
| G/G | 20 (5%) | 127 (6%) | 147 | ||||||||
| 26 | SMAD3_MG_424 | rs12913547 | 15 | 99.6% | C/C | 26 (6%) | 140 (7%) | 166 | 1.039 (0.882, 1.223) |
0.65049 | 0.94139 |
| C/T | 186 (43%) | 771 (39%) | 957 | ||||||||
| T/T | 225 (51%) | 1078 (54%) | 1303 | ||||||||
| 27 | 10Q11_21_MG_429 | rs1746049 | 10 | 99.5% | C/C | 334 (76%) | 1515 (76%) | 1849 | 1.051 (0.840, 1.316) |
0.66062 | 0.94139 |
| C/T | 97 (22%) | 440 (22%) | 537 | ||||||||
| T/T | 6 (1%) | 33 (2%) | 39 | ||||||||
| 28 | MTHFD1L_MG_445 | rs6922269 | 6 | 99.4% | A/A | 31 (7%) | 104 (5%) | 135 | 1.042 (0.865, 1.256) |
0.66254 | 0.94139 |
| A/G | 139 (32%) | 696 (35%) | 835 | ||||||||
| G/G | 267 (61%) | 1184 (60%) | 1451 | ||||||||
| 29 | 5Q21_1_MG_435 | rs436495 | 5 | 98.8% | A/A | 30 (7%) | 116 (6%) | 146 | 0.967 (0.811, 1.153) |
0.70889 | 0.94139 |
| A/G | 142 (33%) | 690 (35%) | 832 | ||||||||
| G/G | 261 (60%) | 1167 (59%) | 1428 | ||||||||
| 30 | SMAD3_MG_452 | rs17228212 | 15 | 99.1% | C/C | 23 (5%) | 108 (5%) | 131 | 1.035 (0.861, 1.243) |
0.71483 | 0.94139 |
| C/T | 153 (35%) | 721 (36%) | 874 | ||||||||
| T/T | 256 (59%) | 1152 (58%) | 1408 | ||||||||
| 31 | SEZ6L_MG_442 | rs6005015 | 22 | 99.5% | C/C | 40 (9%) | 179 (9%) | 219 | 0.974 (0.821, 1.155) |
0.76135 | 0.94139 |
| C/T | 182 (42%) | 857 (43%) | 1039 | ||||||||
| T/T | 215 (49%) | 952 (48%) | 1167 | ||||||||
| 32 | SEZ6L_MG_457 | rs6005016 | 22 | 98.9% | A/A | 2 (0%) | 3 (0%) | 5 | 1.058 (0.727, 1.541) |
0.76788 | 0.94139 |
| A/G | 29 (7%) | 138 (7%) | 167 | ||||||||
| G/G | 401 (93%) | 1836 (93%) | 2237 | ||||||||
| 33 | 2Q36_3_MG_447 | rs7597168 | 2 | 99.4% | C/C | 247 (57%) | 1117 (56%) | 1364 | 1.026 (0.863, 1.220) |
0.77150 | 0.94139 |
| C/T | 165 (38%) | 756 (38%) | 921 | ||||||||
| T/T | 25 (6%) | 112 (6%) | 137 | ||||||||
| 34 | 5Q21_1_MG_441 | rs565928 | 5 | 99.5% | C/C | 275 (63%) | 1247 (63%) | 1522 | 1.024 (0.859, 1.221) |
0.79252 | 0.94139 |
| C/T | 139 (32%) | 636 (32%) | 775 | ||||||||
| T/T | 23 (5%) | 104 (5%) | 127 | ||||||||
| 35 | 9P21_3_MG_437 | rs496892 | 9 | 99.0% | C/C | 104 (24%) | 490 (25%) | 594 | 1.018 (0.881, 1.178) |
0.80582 | 0.94139 |
| C/T | 234 (54%) | 1027 (52%) | 1261 | ||||||||
| T/T | 98 (22%) | 458 (23%) | 556 | ||||||||
| 36 | 5Q21_1_MG_436 | rs449650 | 5 | 99.1% | G/G | 273 (63%) | 1246 (63%) | 1519 | 1.017 (0.854, 1.212) |
0.85091 | 0.94139 |
| G/T | 139 (32%) | 627 (32%) | 766 | ||||||||
| T/T | 23 (5%) | 105 (5%) | 128 | ||||||||
| 37 | CELSR2_MG_438 | rs4970834 | 1 | 99.5% | C/C | 276 (63%) | 1238 (62%) | 1514 | 1.016 (0.842, 1.226) |
0.86520 | 0.94139 |
| C/T | 142 (32%) | 665 (33%) | 807 | ||||||||
| T/T | 19 (4%) | 83 (4%) | 102 | ||||||||
| 38 | 2Q36_3_MG_433 | rs2972147 | 2 | 98.7% | C/C | 174 (40%) | 788 (40%) | 962 | 1.013 (0.871, 1.179) |
0.86648 | 0.94139 |
| C/T | 210 (48%) | 909 (46%) | 1119 | ||||||||
| T/T | 53 (12%) | 270 (14%) | 323 | ||||||||
| 39 | MIA3_MG_430 | rs17465637 | 1 | 99.2% | A/A | 38 (9%) | 147 (7%) | 185 | 1.013 (0.855, 1.201) |
0.88192 | 0.94139 |
| A/C | 153 (35%) | 734 (37%) | 887 | ||||||||
| C/C | 245 (56%) | 1100 (56%) | 1345 | ||||||||
| 40 | 5Q21_1_MG_455 | rs383830 | 5 | 99.0% | A/A | 23 (5%) | 103 (5%) | 126 | 0.988 (0.829, 1.179) |
0.89656 | 0.94139 |
| A/T | 138 (32%) | 630 (32%) | 768 | ||||||||
| T/T | 271 (63%) | 1246 (63%) | 1517 | ||||||||
| 41 | 2Q36_3_MG_461 | rs2943634 | 2 | 97.3% | A/A | 51 (12%) | 246 (13%) | 297 | 1.004 (0.858, 1.175) |
0.95956 | 0.98296 |
| A/C | 194 (46%) | 890 (46%) | 1084 | ||||||||
| C/C | 176 (42%) | 813 (42%) | 989 | ||||||||
| 42 | 1Q31_2_MG_453 | rs1936982 | 1 | 99.0% | C/C | 50 (12%) | 257 (13%) | 307 | 0.999 (0.858, 1.163) |
0.98696 | 0.98696 |
| C/T | 198 (46%) | 858 (43%) | 1056 | ||||||||
| T/T | 184 (43%) | 864 (44%) | 1048 |
Updated on 2008-12-08
