:: Selected publications

Publications from THL

• Auranen K, Mehtälä J, Tanskanen A, S Kaltoft M. Between-Strain Competition in Acquisition and Clearance of Pneumococcal Carriage—Epidemiologic Evidence From a Longitudinal Study of Day-Care Children. Am J Epidemiol, 171(2):169-176, 2010.
  
  
• Erästö P, Hoti F, Granat SM, Mia Z, Mäkelä PH, Auranen K. Modelling multi-type transmission of pneumococcal carriage in Bangladeshi families. Epidemiol Infection, 17:1-12, 2009.
  
  
• Rinta-Kokko H, Dagan R, Givon-Lavi N, Auranen K. Estimation of vaccine efficacy against acquisition of pneumococcal carriage. Vaccine, 27(29):3831-3837, 2009.
  
  
• Hoti F, Erästö P, Leino T, Auranen K. Outbreaks of Streptococcus pneumoniae carriage in day care cohorts in Finland – implications for elimination of transmission. BMC Infect Dis, 9:102, 2009.
  
  
• Granat SM, Ollgren J, Herva E, Mia Z, Auranen K, Mäkelä PH. Epidemiological evidence for serotype independent acquired immunity to pneumococcal carriage. J Infect Dis, 200:99-106, 2009.
  
  
• Varvio SL, Auranen K, Arjas E, Mäkelä PH. Dichotomous evolution of the capsular genome in Streptococcus pneumoniae. J Infect Dis, 200(7):99-106, 2009.

• Leino T, Hoti F, Syrjänen R, Tanskanen A, Auranen K. Clustering of serotypes in a longitudinal study of Streptococcus pneumoniae carriage in three day care centres. BMC Infect Dis, 8:173, 2008.

Manuscripts in preparation at THL

• Auranen et al.: Characterising the extent of clustering for pathogens with multiple strains, in preparation, 2011.
  
  
• Auranen et al.: Design questions for colonisation endpoints, in preparation, 2011.
  
  
• Auranen et al.: Cross-sectional measurement of vaccine efficacy against pathogens with multiple strains, in preparation, 2011.
  
  
• Erästö et al.: Modeling transmission of multitype infectious agents - Application to carriage of Streptococcus pneumoniae, in preparation, 2011.
  
  
• Erästö et al.: The effect of sampling interval on the estimation of transmission dynamics, in preparation, 2011.
  
  
• Mehtälä et al.: The effect of imperfect detection on estimation of interactions between biological agents interactions - application to nasopharyngeal colonisation of Streptococcus pneumoniae, in preparation, 2011.
  
  
• Mehtälä et al.: Optimal designs for discretely observed binary Markov processes, submitted.
  
  
• Nurhonen et al.: Indirect effects of vaccination in silico - a mathematical model of pneumococcal transmission and vaccination, in preparation, 2011.
  
  
• Simell et al.: Serum IgM antibodies contribute to the high opsonophagocytic activities in toddlers immunized with a single dose of 9-valent pneumococcal conjugate vaccine, in preparation, 2011.
  
  
• Simell et al.: Association of serotype-specific antibody concentrations and functional antibody titers with subsequent pneumococcal carriage in toddlers immunized with 9-valent pneumococcal conjugate vaccine, in preparation, 2011.

Publications from other PneumoCarr partners

UM, Australia:

• Russell FM, Balloch A, Tang ML, Carapetis JR, Licciardi P, Nelson J, Jenney AW, Tikoduadua L, Waqatakirewa L, Pryor J, Byrnes GB, Cheung YB, Mulholland EK. Immunogenicity following one, two, or three doses of the 7-valent pneumococcal conjugate vaccine. Vaccine, 27(41):5685-91, 2009.
  
  
• Jin P, Kong F, Xiao M, Oftadeh S, Zhou F, Liu C, Russell F, Gilbert GL. First report of putative Streptococcus pneumoniae serotype 6D among nasopharyngeal isolates from Fijian children. J Infect Dis, 200(9):1375-80, 2009.
  
  
• Russell FM, Carapetis JR, Balloch A, Licciardi PV, Jenney AWJ, Tikoduadua L, Waqatakirewa L, Pryor J, Nelson J, Byrnes GB, Cheung YB, Tang MLK, Mulholland EK. Hyporesponsiveness to re-challenge dose following pneumococcal polysaccharide vaccine at 12 months of age, a randomized controlled trial. Vaccine, 28(19):3341-9, 2010.
  
  
• Russell FM, Carapetis JR, Tikoduadua L, Chandra R, Seduadua A, Satzke C, Pryor J, Buadromo E, Waqatakirewa L, Mulholland EK. Invasive pneumococcal disease in Fiji: clinical syndromes, epidemiology, and the potential impact of pneumococcal conjugate vaccine. Pediatr Infect Dis J, 29(9):870-2, 2010.
  
  
• Russell FM, Licciardi PV, Balloch A, Biaukula V, Tikoduadua L, Carapetis JR, Nelson J, Jenney AWJ, Waqatakirewa L, Colquhoun S, Cheung YB, Tang MLK, Mulholland EK. Safety and immunogenicity of the 23-valent pneumococcal polysaccharide vaccine at 12 months of age, following one, two, or three doses of the 7-valent pneumococcal conjugate vaccine in infancy. Vaccine, 28(18):3086-94, 2010.
  
  
• Balloch A, Licciardi PV, Russell FM, Mulholland EK, Tang ML. Infants aged 12 months can mount adequate serotype-specific IgG responses to pneumococcal polysaccharide vaccine. J Allergy Clin Immunol, 126(2):395-7, 2010.

MRC Laboratories , the Gambia:

• Hill PC, Townend J, Antonio M, Akisanya B, Ebruke C, Lahai G, Greenwood BM, Adegbola RA. Transmission of Streptococcus pneumoniae in rural Gambian villages: a longitudinal study. Clin Infect Dis, 50(11):1468-76, 2010.
  
  
• Cheung YB, Zaman SM, Nsekpong ED, Van Beneden CA, Adegbola RA, Greenwood B, Cutts FT. Nasopharyngeal carriage of Streptococcus pneumoniae in Gambian children who participated in a 9-valent pneumococcal conjugate vaccine trial and in their younger siblings. Pediatr Infect Dis J, 28(11):990-5, 2009.
  
  
• Ota MO, Akinsola A, Townend J, Antonio M, Enwere G, Nsekpong D, Bojang A, Saaka M, Burton RL, Zaman A, Goldblatt D, Adegbola RA. The immunogenicity and impact on nasopharyngeal carriage of fewer doses of conjugate pneumococcal vaccine immunization schedule. Vaccine, 2011 (in press).

BGU, Israel:

• Givon-Lavi N, Greenberg D, Dagan R. Immunogenicity of alternative regimens of the conjugated 7-valent pneumococcal vaccine: a randomized controlled trial. Pediatr Infect Dis J, 29(8):756-62, 2010.
  
  
• Dagan R, Givon-Lavi N, Greenberg D, Fritzell B, Siegrist CA. Nasopharyngeal carriage of Streptococcus pneumoniae shortly before vaccination with a pneumococcal conjugate vaccine causes serotype-specific hyporesponsiveness in early infancy. J Infect Dis, 201(10):1570-9, 2010.

RITM, and ARIVAC Consortium, Manila the Philippines:

• Väkeväinen M, Soininen A, Lucero M, Nohynek H, Auranen K, Mäkelä PH, Williams G, Käyhty H, for the ARIVAC Consortium. Serotype-specific hyporesponsiveness to pneumococcal conjugate vaccine in infants carrying pneumococcus at the time of vaccination. J Pediatr, 157(5):778-83, 2010.

RMPRU, Johannesburg, South Africa:

• Madhi S, Adrian P, Cotton M, McIntyre J, Jean-Philippe P, Meadows S, Nachman S, Käyhty H, Klugman KP, Violari A on behalf of the CIPRA 4 team. Effect of HIV infection status and anti-retroviral treatment on quantitative and qualitative antibody responses to pneumococcal conjugate vaccine in infants. J Infect Dis. 2010:202:355-61.