FINNISH RESEARCH PROGRAMME
ON ENVIRONMENTAL HEALTH
SYTTY
 
 

DETERMINANTS OF SENSITIVITY TO DIOXIN-INDUCED HEALTH EFFECTS

Project leader: Matti Viluksela, National Public Health Institute (KTL), Laboratory of Toxicology, P.O. Box 95, FIN-70701 Kuopio, Finland, tel. +358-17-201329, e-mail: Matti.Viluksela@ktl.fi
 

PUBLICATIONS

(Updated May 21, 2002)

Articles in international scientific journals

Jämsä T., Viluksela M., Tuomisto J.T., Tuomisto J., Tuukkanen J. 2001.  Effects of 2,3,7,8-tetrachlorodibenzo-p-dioxin on bone in two rat strains with different aryl hydrocarbon receptor structures. J. Bone Miner. Res. 16, 1812-1820.

Kattainen H., Tuukkanen J., Simanainen U., Tuomisto J.T., Kovero O., Lukinmaa P.-L., Alaluusua S., Tuomisto J., Viluksela M. 2001.  In utero / lactational TCDD exposure impairs the molar tooth development in rats. Toxicol. Appl. Pharmacol. 174, 216-224.

Submitted articles

Tuomisto J.T., Viluksela M., Pohjanvirta R., Tuomisto J. 1999.  The Ah receptor and a novel gene determine acute toxic responses to TCDD: Segregation of the resistant alleles to different rat lines. Toxicol. Appl. Pharmacol. 155, 71-81.

Simanainen U., Tuomisto J.T., Tuomisto J., Viluksela M. 2002a.  Structure-activity relationships and dose-responses of polychlorinated dibenzo-p-dioxins (PCDDs) for short-term effects in TCDD-resistant and TCDD–sensitive rat strains. Toxicol. Appl. Pharmacol. In press.

Kattainen H., Alaluusua S., Tuomisto J., Viluksela M. 2002.  Effect of in utero / lactational TCDD exposure on rat molar development: The role of exposure time. Submitted.

Kiukkonen A., Viluksela M., Sahlberg C., Alaluusua S., Tuomisto J.T., Tuomisto J., Lukinmaa P.-L.  Response of the incisor tooth to 2,3,7,8-tetrachlorodibenzo-p-dioxinin dioxin-resistant and dioxin-sensitive rat strains. Submitted.

Niittynen M., Tuomisto J.T., Auriola S., Pohjanvirta R., Syrjälä P., Simanainen U., Viluksela M., Tuomisto J. 2002.  2,3,7,8-Tetrachlorodibenzo-p-dioxin (TCDD) induces accumulation of biliverdin and hepatic peliosis in TCDD-semiresistant rats. Submitted.

Simanainen U., Tuomisto J.T., Tuomisto J., Viluksela M. 2002b.  Dose-response analysis on short term effects of TCDD in three differentially susceptible rat lines: Two types of aryl hydrocarbon receptor mediated effects. Submitted.

Articles in international scientific compilation works and international scientific conference proceedings

Kattainen H., Simanainen U., Tuomisto J.T., Kovero O., Alaluusua S., Tuomisto J., Viluksela M.: In utero/lactational TCDD exposure impairs the molar tooth development in rats. Organohalog. Comp. 2000; 49:229-232.

Simanainen U., Tuomisto J.T., Kattainen H., Tuomisto J., Viluksela M.: Effects of in utero and lactational TCDD exposure on male reproduction pattern in three differentially TCDD sensitive rat lines. Organohalog. Comp. 2000; 49:342-344.

Viluksela M., Simanainen U., Tuomisto J.T., Pohjanvirta R., Harper P.A., Okey A.B., Tuomisto J. 1998. Characterization of the deviant structure-activity relationship for chlorinated dibenzo-p-dioxins (CDDs) in the resistant Han/Wistar rats. Organohalog. Comp. 38, 287-290.

Viluksela M., Jämsä T., Tuomisto J.T., Tuomisto J.,Tuukkanen J.: Effects of TCDD on bone quality in a TCDD-sensitive and a TCDD-resistant rat strain. Organohalog. Comp. 2000; 49:132-134.

Other scientific publications

Tuomisto J.T.: TCDD: a challenge to mechanistic toxicology. Publications of the National Public Health Institute A7/1999. 67 p. Doctoral dissertation.

Viluksela M., Simanainen U.: Endocrine effects of organohalogen compounds (In Finnish). Ympäristö ja Terveys, 2000; 31:56-58.
 

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